Molecular pathogenesis of root dentin caries

Oral Diseases

Volumn 5, Issue 2, 1999, Pages 92-99

  Dung, Tony Shing Zeng ^a   Liu, A H H ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Dentin caries; Molecular pathogenesis; Tooth root

Indexed keywords

COLLAGEN FIBER; COLLAGENASE; HYDROXYAPATITE; PROTEINASE;

ACTINOMYCES VISCOSUS; DEMINERALIZATION; DENATURATION; DENTAL CARIES; DENTIN; ENAMEL; EXTRACELLULAR MATRIX; PRIORITY JOURNAL; REVIEW; STREPTOCOCCUS MUTANS; TOOTH DISEASE; TOOTH PLAQUE; TOOTH PULP; TOOTH ROOT;

EID: 0032922345     PISSN: 1354523X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1601-0825.1999.tb00071.x     Document Type: Review

References (97)

1. Andujar MB, Hartmann DJ, Caillot G et al (1989). Immunolocalization of Cathepsin D in dental tissues. Matrix 9: 397-404.
2. Arends J, Christoffersen J, Ruben J et al (1989a). Remineralization of bovine dentin in vitro. Caries Res 23: 309-314.
3. Arends J, Ruben J, Jongebloed WL ( 1989b). Dentin caries in vivo. Caries Res 23: 36-41.
4. Aronson NN (1972). Degradation of glycoproteins by lysosomal enzymes. In: Gottschalk A. ed. Glycoproteins. Elsevier: Amsterdam, pp 1211-1227.
5. Boonstra WD, ten Bosch JJ, Arends J (1990). Protein and mineral release during in vitro demineralization of bovine dentin. J Biol Buccale 17: 43-48.
6. Bornstein P, Kang AH, Piez KA (1966). The limited cleavage of native collagen with chymotrypsin, trypsin, and cyanogen bromide. Biochemistry 5: 3803-3812.
7. Boskey AL, Maresca M, Doty S et al (1990). Concentration-dependent effects of dentin phosphorylation in the regulation of in vitro hydroxyapatite formation and growth. Bone Mineral 11: 55-65.
8. Bosshardt DD, Nanci A (1997). Immunodetection of enamel-and cementum-related (bone) proteins at the enamel-free area and cervical portion of the tooth in rat molars. J Bone Miner Res 12: 367-379.
9. Bosshardt DD, Zalzal S, Mckee MD et al (1998). Developmental appearance and distribution of bone sialoprotein and osteopontin in human and rat cementum. Anat Rec 250: 13-33.
10. Butler WT (1984a). Dentin collagen: chemical structure and role in mineralization. In: Linde A ed. Dentin and dentinogenesis. Vol II, CRC Press: Boca Roton, Florida, pp 37-54.
11. Butler WT (1984b). Matrix macromolecules of bone and dentin. Collagen Rel Res 4: 297-307.
12. Butler WT (1998). Dentin matrix proteins. Eur J Oral Sci 106 (Suppl 1): 204-210.
13. Chandrasekhar S, Kleinman HK, Hassell JR et al (1984). Regulation of type I collagen fibril assembly by link protein and proteoglycans. Collagen Rel Res 4: 323-338.
14. Chang SR, Chiego Jr D, Clarkson BH (1996). Characterization and identification of a human dentin phosphophoryn. Calcif Tissue Int 59: 149-153.
15. Clarkson B, Feagin F, McCurdy S et al (1991). Effects of phosphoprotein moieties on the remineralization of human root caries. Caries Res 25: 166-173.
16. Clarkson BH, Hall DL, Heilman JR et al (1986). Effect of proteolytic enzymes on carries lesion formation in vitro. J Oral Pathol 15: 423-429.
17. Dayan G, Binderman I, Mechanic GL (1983). A preliminary study of activation of collagenase in carious human dentin matrix. Arch Oral Biol 28: 185-187.
18. Drake MP, Davison PF, Bump S et al (1966). Action of proteolytic enzymes on tropocollagen and insoluble collagen. Biochemistry 5: 301-312.
19. D'Souza RN, Cavender A, Sunavala G et al (1997). Gene expression patterns of murine dentin matrix protein 1 (Dmpl) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo. J Bone Miner Res 12: 2040-2049.
20. Dumas J, Hurion N, Weill R et al (1985). Collagenase in mineralized tissues of human teeth. FEBS Lett 187: 51-55.
21. Dung S-Z, Li Y, Dunipace AJ et al (1994). Degradation of insoluble bovine collagen and human dentin collagen pretreated in vitro with lactic acid, pH 4.0 and 5.5. Arch Oral Biol 39: 901-905.
22. Dung S-Z, Gregory RL, Li Y et al (1995). Effect of lactic acid and proteolytic enzymes on the release of organic matrix components from human root dentin. Caries Res 29: 483-489.
23. Eastoe JE (1967). Chemical organization of the organic matrix of dentin. In: Miles AEW, ed. Structural and chemical organization of teeth. Academic Press: London, pp 279-314.
24. 1 and collagenolytic cathepsin: a comparative study of the properties of the two enzymes in the degradation of native collagen. J Biochem 153: 199-109.
25. Featherstone JDB, McIntyre JM, Fu J (1987). Physico-chemical aspects of root caries progression. In: Thylstrup A, Leach SA, Qvist V, eds. Dentin and dentin reaction in the oral cavity. IRL Press: Oxford, pp 127-137.
26. Frank RM (1990). Structure events in the caries process in enamel, cementum and dentin. J Dent Res 69 (Spec Iss): 659-666.
27. Frank RM, Steuer P, Hemmerle J (1989). Ultrastructure study on human root caries. Caries Res 23: 209-217.
28. Fukae M, Kaneko I, Tanabe T et al (1991). Metalloproteinases in the mineralized compartments of porcine dentine as detected by substrate-gel electrophoresis. Arch Oral Biol 36: 567-573.
29. Fureth R (1971). Further observation on the fine structure of oral exposed and carious human dental cementum. Arch Oral Biol 16: 71-85.
30. Gage JP, Francis MJO, Triffitt JT (1989). Collagen and dentin matrix. Wright: London, pp 8-47.
31. Geiger SB, Harper E (1981). The inhibition of human gingival collagenase by an inhibitor extracted from human teeth. J Periodontal Res 16: 8-12.
32. Gibbons RJ, MacDonald JB (1961). Degradation of collagenous substrates by Bacteroides melaninogenicus. J Bacteriol 81: 614-621.
33. Hagihara Y, Kaminishi H, Cho T et al (1988). Degradation of human dentine collagen by an enzyme produced by the yeast Candida albicans. Arch Oral Biol 33: 617-619.
34. Harada K, Oida S, Sasaki S et al (1990). Chondrocyte-like colony formation of mesenchymal cells by dentin extracts in agarose gel culture. J Dent Res 69: 1555-1559.
35. Heinegard D, Paulsson M (1984). Structure and metabolism of proteoglycans. In: Piez KA, Reddi AH, eds. Extracellular matrix biochemistry. Elsevier: New York, pp 317-328.
36. Hirst KL, Ibaraki-O'Connor K, Young MF et al (1997). Cloning and expression analysis of the bovine dentin matrix acidic phosphoprotein gene. J Dent Res 76: 754-760.
37. Hjerpe A, Engfeldt B (1976). Proteoglycans of dentin and predentin. Calcif Tissue Res 22: 173.
38. Hoppenbrouwer PM, Drissens FC, Borggreven JM (1986). The vulnerability of unexposed human dental roots to demineralization. J Dent Res 65: 955-958.
39. Hoppenbrouwer PM, Drissens FC, Borggreven JM (1987). The mineral solubility of human dental root. Arch Oral Biol 32: 319-322.
40. Johansen E, Parks HF (1961). Electron-microscopic observations on soft carious human dentin. J Dent Res 40: 235-248.
41. Katz S, Park KK, Palenik CJ (1987). In-vitro root caries studies. J Oral Med 42: 40-48.
42. Kawasaki K, Featherstone JDB (1997). Effects of collagenase on root demineralization. J Dent Res 76: 588-595.
43. Kleter GA, Damen JJM, Everts V et al (1994). The influence of the organic matrix on demineralization of bovine root dentin in vitro. J Dent Res 73: 1523-1529.
44. Klont B, ten Cate JM (1987). Denaturation and degradation of dentin collagen during dentinal caries: possible mechanisms. In: Thylstrup A, Leach SA, Qvist V et al, eds. Dentin and dentin reactions in oral cavity. IRL Press: Oxford, pp 155-164.
45. Klont B, ten Cate JM (1990). Release of organic matrix components from bovine incisor roots during in vitro lesion formation. J Dent Res 69: 896-900.
46. Klont B, Damen JJM, ten Cate JM et al (1991). Degradation of bovine incisor root collagen in an in vitro model. Arch Oral Biol 36: 299-304.
47. Koutsoukos PG, Nancollas GH (1986). The adsorption of inorganic phosphate by collagen. Colloids Surfaces 17: 81-90.
48. Koutsoukos PG, Nancollas GH (1987). The mineralization of collagen in vitro. Colloids Surfaces 28: 95-108.
49. Kowashi Y, Cimasoni G, Matter J (1980). Collagen breakdown by gingival collagenase and elastase. Experientia 36: 395-396.
50. Kowashi Y, Jaccard F, Cimasoni G (1979). Increase of free collagenase and neutral protease activities in the gingival crevice during experimental gingivitis in man. Arch Oral Biol 24: 645-650.
51. Kuboki Y, Mechanic GL (1982). Comparative molecular distribution of cross-links in bone and dentin collagen. Structure-function relationship. Calcif Tissue Int 34: 306-308.
52. Kuboki Y, Oghushi K, Fusayama T (1977). Collagen biochemistry of the two layers of dentin caries. J Dent Res 56: 1233-1237.
53. Kuboki Y, Tanzer ML, Mechanic GL (1973). Isolation of polypeptides containing the intermolecular cross-link d-d′-dihydroxylysinonorleucine from dentin collagen. Arch Biochem Biophy 158: 106-115.
54. Kuboki Y, Tsuzaki M, Sasaki S et al (1981). Location of the intermolecular cross-links in bovine dentin collagen, solubilization with trypsin and isolation of cross-link peptides containing dihydroxylysinonorleucine and pyridinoline. Biochem Biophys Res Commun 15: 119-126.
55. Linde A (1987). Dentin: structure, chemistry and formation. In: Thylstrup A, Leach SA, Qvist V et al, eds. Dentin and dentin reaction in the oral cavity. IRL Press: Oxford, pp 17-26.
56. Linde A (1988). Differences between non-collagenous protein content of rat incisor and permanent bovine dentin. Scand J Dent Res 96: 188-198.
57. Linde A (1989). Dentin matrix proteins: composition and possible functions in calcification. Anat Rec 224: 154-166.
58. Linde A, Brown M, Butler WT (1980). Non-collagenous proteins of dentin. J Biol Chem 255: 5931-5942.
59. Linde A, Robins SP (1988). Quantitative assessment of collagen cross-links in dissected predentin and dentin. Collagen Rel Res 8: 443-450.
60. Loesche WJ, Paunio KU, Woolfolk MP et al (1974). Collagenolytic activity of dental plaque associated with periodontal pathology. Infect Immun 9: 329-336.
61. MacDougall M, Zeichner-David M, Slavkin HC (1989). Characterization of extracellular and nascent dentin phosphoproteins. Connect Tissue Res 22: 71-77.
62. Mathews MB (1965). The interaction of collagen and mucopolysaccharide. Model for connective tissue. Biochem J 96: 710.
63. Mayrand D, Grenier D (1985). Detection of collagenase activity in oral bacteria. Can J Microbiol 14: 288-294.
64. McCurdy S, Clarkson B, Speirs R et al (1990). Phosphoprotein extraction from the dentine/cementum complex of human tooth roots. Arch Oral Biol 35: 347-357.
65. McKee MD, Zalzal S, Nanci A (1996). Extracellular matrix in tooth cementum and mantle dentin: localization of osteopontin and other noncollagenous proteins, plasma proteins, and glycoconjugates by electron microscopy. Anat Rec 245: 293-312.
66. MacDougall M, Simmons D, Luan X et al (1997). Dentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. J Biol Chem 272: 835-842.
67. MacNeil RL, Berry J, Strayhorn C et al (1996). Expression of bone sialoprotein mRNA by cells lining the mouse tooth root during cementogenesis. Arch Oral Biol 41: 827-835.
68. Montes GS, Junqueira LCU (1988). Histochemical localization of collagen and of proteoglycans in tissues. In: Nimni ME, ed. Collagen. VoI II. CRC Press: Boca Raton, FL, pp 41-72.
69. Munksgaard EC (1979). Collagen in dentin. J Biol Buccale 7: 131-135.
70. Nemethy G, Scheraga HA (1986). Stabilization of collagen fibrils by hydroxyproline. Biochemistry 25: 3184-3188.
71. Newbrun E (1986). Prevention of root caries. Gerodontology 5: 33-41.
72. Nyvad B, Fejerskov O (1990). Pattern of bacterial invasion and tissue break-down in human experimental root surface caries. J Dent Res 69 (Spec Iss): 358 (Abstract 1996).
73. Ogaard B, Rolla G, Arend J (1988). In vitro progress of enamel and root surface lesions under plaque as a function of time. Caries Res 22: 302-305.
74. Phankosol P, Ettinger RL, Hicks MJ et al (1985). Histopathology of the initial lesion of the root surface: an in vitro study. J Dent Res 64: 804-809.
75. Rahanen L, Zaragoza EJ, Uitto J (1983). Conformational stability of type I collagen triple helix: evidence for temporary and local relaxation of the protein conformation using a proteolytic probe. Arch Biochem Biophy 223: 562-571.
76. Rahemtulla F (1992). Proteoglycans of oral tissues. Crit Rev Oral Biol Med 3: 135-162.
77. Rahemtulla F, Prince CW, Butler WT (1984). Isolation and partial characterization of proteoglycans from rat incisors. Biochem J 218: 877-885.
78. Rahima M, Veis A (1988). Two classes of dentin phosphophoryns, from a wide range of species, contain immunologically cross-reactive epitope regions. Calcif Tissue Int 42: 104-112.
79. Ritchie HH, Shigeyama Y, Somerman et al (1996). Partial cDNA sequencing of mouse dentine sialoprotein and detection of its specific expression by odontoblasts. Arch Oral Biol 41: 571-575.
80. Robertson PB, Lantz M, Marucha PT et al (1982). Collagenolytic activity associated with Bacteroides species and Actinobacillus actinomycetemcomitans. J Periodontal Res 17: 275-283.
81. Roden L (1980). Structure and metabolism of connective tissue proteoglycans. In: Lennarz WJ, ed. The biochemistry of glycoproteins and proteoglycans. Plenum Press: New York, pp 286-314.
82. Schupbach P, Guggenheim B, Lutz F (1989). Human root caries: Histopathology of initial lesions in cementum and dentin. J Oral Path Med 18: 146-156.
83. Schupbach P, Guggenheim B, Lutz F (1990). Human root caries: histopathology of advanced lesions. Caries Res 24: 145-158.
84. Selvig KA (1968). Ultrastructural changes in humai dentin exposed to a weak acid. Arch Oral Biol 13: 719-734.
85. Smith AJ, Smith G (1984). Proteolytic activity of rabbit incisor dentine. Arch Oral Biol 29: 1049-1050.
86. Steinfort JS, van den Bos T, Beertsen W (1989). Differences between enamel-related and cementum-related dentin in rat incisor with special emphasis on the phosphoprotein. J Biol Chem 264: 2840-2845.
87. Stetler-Stevenson WG, Veis A (1986). Type I collagen shows a specific binding affinity for bovine dentin phosphophoryn. Calcif Tissue Int 38: 135-141.
88. Suido H, Nakamura M, Mashimo et al (1986). Arylaminopeptidase activities of oral bacteria. J Dent Res 65: 1335-1340.
89. Sundqvist G, Carlsson J, Hanstrom L (1987). Collagenolytic activity of black-pigmented Bacteroides species. J Periodontal Res 22: 300-306.
90. Takagi Y, Nagai H, Sasaki S (1988). Difference in non-collagenous matrix composition between crown and root dentin of bovine incisor. Calcif Tissue Int 42: 97-103.
91. 2HS glycoprotein in dentin. Calcif Tissue Int 47: 40-45.
92. Tjaderhane L, Larjava H, Sorsa T et al (1998). The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions. J Dent Res 77: 1622-1629.
93. Veis A, Sabsay B (1987). The collagen of mineralized martrices. In: Peck WA, ed. Bone and mineral research Vol 5. Elsevier Science: Amsterdam, pp 1-63.
94. Veis A, Schlueter RJ (1964). The macromolecular organization of dentin matrix collagen. I Characterization of dentin collagen. Biochemistrry 3: 1650.
95. Walter C, Eyre DR (1983). Collagen crosslinks in human dentin: increasing content of hydroxypyridinium residues with age. Calcif Tissue Int 35: 401-405.
96. Weller M (1979). Enzymes which catalyse the dephosphorylation of proteins, In: Weller M, ed. Protein phosphorylation. Pion Limited: London, pp 49-64.
97. Werb Z (1982). Degradation of collagen. In: Weiss JB, Jayson MIV, eds. Collagen in health and disease. Churchill Livingstone: New York, pp 121-134.