Binding characteristics of pancreatic polypeptide receptors on rat hepatic membranes

Acta Pharmacologica Sinica

Volumn 20, Issue 1, 1999, Pages 59-64

  Zhang, Xin Tang ^a   Yao, Shi Yin ^a   Xu, Ying Gao ^a   Zhu, Shang Quan ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Binding sites; Cell membrane; Competitive binding; Liver; Pancreatic hormones; Pancreatic polypeptide; Peptide receptors

Indexed keywords

IODINE 125; PANCREAS POLYPEPTIDE; RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; LIVER MEMBRANE; MALE; NONHUMAN; RAT; RECEPTOR BINDING; TEMPERATURE;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL MEMBRANE; DUCKS; LIVER; PANCREAS; PANCREATIC POLYPEPTIDE; RATS; RECEPTORS, GASTROINTESTINAL HORMONE; SPECIES SPECIFICITY; SWINE;

EID: 0032922251     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Kimmel JR, Hayden LJ, Pollock HG. Isolation and characterization of a new pancreatic polypeptide hormone. J Biol Chem 1975; 250: 9369-76.
2. Lin TM, Chance RE. Candidate hormones of the gut. VI. Bovine pancreatic polypeptide (BPP) and avian pancreatic polypeptide (APP). Gastroenterology 1974; 67: 737-8.
3. Beglinger C, Taylor IL, Grossman MI, Solomon TE. Pancreatic polypeptide inhibits exocrine pancreatic responses to six stimulants. Am J Physiol 1984; 246 (3 Pt 1): G286-91.
4. Adrian TE, Mitchenere P, Sagor G, Bloom SR. Effect of pancreatic polypeptide on gallbladder pressure and hepatic bile secretion. Am J Physiol 1982; 243: G204-7.
5. Sun YS, Brunicardi FC, Druck P, Walfisch S, Berlin SA. Reversal of abnormal glucose matabolism in chronic pancreatitis by administration of pancreatic polypeptide. Am J Surg 1986; 151: 130-40.
6. Xu YG, Zhu SQ, Zhang YS. Isolation and sequence determination of duck pancreatic polypeptide. Chin J Biochem Biophy 1993; 25: 85-90.
7. Gilbert WR, Frank BH, Gavin JR III, Gingerich RL. Characterization of specific pancreatic polypeptide receptors on basolateral membranes of the canine small intestine. Proc Natl Acad Sci USA 1988; 85: 4745-9.
8. Whitcomb DC, Taylor IL, Vigna SR. Characterization of saturable binding sites for circulating pancreatic polypeptide in rat brain. Am J Physiol 1990; 259 (4 Pt 1): G687-91.
9. Nguyen TD, Wolfe MS, Heintz GG, Whitcomb DC, Taylor IL. High affinity binding proteins for pancreatic polypeptide on rat liver membranes. J Biol Chem 1992; 267: 9416-21.
10. Cuatrecasas P. Isolation of the insulin receptor of liver and fat-cell membranes. Proc Natl Acad Sci USA 1972; 69: 318-22.
11. Hartree EF. Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal Biochem 1972; 48: 422-7.
12. Gu JL, Zhang XT. Labelling of insulin and deshexapeptide insulin with radioactive iodine utilizing a solid phase oxidizer-1, 3, 4, 6 tetrachloro-3α, 6α-diphenylglycoluril. Acta Biochim Biophys Sin 1986; 18: 277-83.
13. Linde S, Hansen B. Monoiodoinsulin specifically substituted in Tyr A 14 or Tyr A 19. Int J Pept Protein Res 1980; 15: 495-502.
14. Scatchard G. The attractions of proteins for small molecules and ions. Ann NY Acad Sci 1949; 51: 660-72.
15. McKay DM, Shaw C, Thim L, Johnston CF, Halton DW, Fairweather I, et al. The complete primary structure of pancreatic polypeptide from the European common frog, Rana temporaria. Regul Pept 1990; 31: 187-97.