메뉴 건너뛰기




Volumn 6, Issue 1, 1999, Pages 98-106

Pulmonary inflammation associated with repeated, prenatal exposure to an E1, E3-deleted adenoviral vector in sheep

Author keywords

Fetal therapy; Fetal treatment; Fetus; Gene therapy; Gene transfer

Indexed keywords

BACTERIAL ENZYME; BETA GALACTOSIDASE; VIRUS VECTOR;

EID: 0032921771     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300804     Document Type: Article
Times cited : (44)

References (42)
  • 1
    • 0027448270 scopus 로고
    • Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer
    • Mastrangeli A et al. Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. J Clin Invest 1993; 91: 225-234.
    • (1993) J Clin Invest , vol.91 , pp. 225-234
    • Mastrangeli, A.1
  • 2
    • 0027984919 scopus 로고
    • In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung
    • Yei SP et al. In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung. Hum Gene Ther 1994; 5: 731-744.
    • (1994) Hum Gene Ther , vol.5 , pp. 731-744
    • Yei, S.P.1
  • 3
    • 0027407198 scopus 로고
    • In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors
    • Lemarchand P, Jones M, Yamada I, Crystal RG. In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ Res 1993; 72: 1132-1138.
    • (1993) Circ Res , vol.72 , pp. 1132-1138
    • Lemarchand, P.1    Jones, M.2    Yamada, I.3    Crystal, R.G.4
  • 4
    • 0029127914 scopus 로고
    • Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero
    • Vincent M et al. Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero. Hum Gene Ther 1995; 6: 1019-1028.
    • (1995) Hum Gene Ther , vol.6 , pp. 1019-1028
    • Vincent, M.1
  • 5
    • 0028803618 scopus 로고
    • Intra-amniotic administration of an adenoviral vector for gene transfer to fetal sheep and mouse tissues
    • Holzinger A et al. Intra-amniotic administration of an adenoviral vector for gene transfer to fetal sheep and mouse tissues. Pediatr Res 1995; 38: 1-7.
    • (1995) Pediatr Res , vol.38 , pp. 1-7
    • Holzinger, A.1
  • 6
    • 0029046114 scopus 로고
    • Adenovirus-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo
    • McCray PB Jr et al. Adenovirus-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo. J Clin Invest 1995; 95: 2620-2632.
    • (1995) J Clin Invest , vol.95 , pp. 2620-2632
    • McCray Jr., P.B.1
  • 7
    • 0027735897 scopus 로고
    • Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: Toxicity study
    • Simon RH et al. Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study. Hum Gene Ther 1993; 4: 771-780.
    • (1993) Hum Gene Ther , vol.4 , pp. 771-780
    • Simon, R.H.1
  • 8
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
    • Yang Y et al. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA 1994; 91: 4407-4411.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4407-4411
    • Yang, Y.1
  • 9
    • 0028991829 scopus 로고
    • Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice
    • Zsengeller ZK et al. Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice. Hum Gene Ther 1995; 6: 457-467.
    • (1995) Hum Gene Ther , vol.6 , pp. 457-467
    • Zsengeller, Z.K.1
  • 10
    • 0028318416 scopus 로고
    • Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats
    • Zabner J et al. Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats. Nat Genet 1994; 6: 75-83.
    • (1994) Nat Genet , vol.6 , pp. 75-83
    • Zabner, J.1
  • 11
    • 0005984244 scopus 로고
    • 'Activity acquired tolerance' of foreign cells
    • Billingham RE, Brent L, Medawar PB. 'Activity acquired tolerance' of foreign cells. Nature 1953; 172: 603-606.
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 14
    • 6544241068 scopus 로고
    • Development of normal and abnormal immune functions in humans
    • Cooper EL, Nisbet-Brown E (eds). Oxford University Press: Oxford
    • Dosch H-M, Hui MF, Doherty PJ. Development of normal and abnormal immune functions in humans. In: Cooper EL, Nisbet-Brown E (eds). Developmental Immunology. Oxford University Press: Oxford, 1993, pp 452-470.
    • (1993) Developmental Immunology , pp. 452-470
    • Dosch, H.-M.1    Hui, M.F.2    Doherty, P.J.3
  • 15
    • 0028086149 scopus 로고
    • In utero hematopoietic stem cell transplantation and gene therapy
    • Crombleholme TM, Bianchi DW. In utero hematopoietic stem cell transplantation and gene therapy. Semin Perinatol 1994; 18: 376-384.
    • (1994) Semin Perinatol , vol.18 , pp. 376-384
    • Crombleholme, T.M.1    Bianchi, D.W.2
  • 16
    • 0029848406 scopus 로고    scopus 로고
    • Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow
    • Flake AW et al. Treatment of X-linked severe combined immunodeficiency by in utero transplantation of paternal bone marrow. New Engl J Med 1996; 335: 1806-1810.
    • (1996) New Engl J Med , vol.335 , pp. 1806-1810
    • Flake, A.W.1
  • 17
    • 0022556210 scopus 로고
    • The ontogeny and comportment of lymphoid cells in fetal and neonatal sheep
    • Morris B. The ontogeny and comportment of lymphoid cells in fetal and neonatal sheep. Immunol Rev 1986; 91: 219-233.
    • (1986) Immunol Rev , vol.91 , pp. 219-233
    • Morris, B.1
  • 18
    • 0029955391 scopus 로고    scopus 로고
    • Neonatal cotton rats do not exhibit destructive immune responses to adenoviral vectors
    • Zepeda M, Wilson JM. Neonatal cotton rats do not exhibit destructive immune responses to adenoviral vectors. Gene Therapy 1996; 3: 973-979.
    • (1996) Gene Therapy , vol.3 , pp. 973-979
    • Zepeda, M.1    Wilson, J.M.2
  • 19
    • 0029970829 scopus 로고    scopus 로고
    • Long-term correction of bilirubin-UDP-glucurononsyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period
    • Takahashi M et al. Long-term correction of bilirubin-UDP-glucurononsyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period. J Biol Chem 1996; 271: 26536-26542.
    • (1996) J Biol Chem , vol.271 , pp. 26536-26542
    • Takahashi, M.1
  • 20
    • 0029968305 scopus 로고    scopus 로고
    • Circumventing the immune response to adenovirus-mediated gene therapy
    • Kass-Eisler A et al. Circumventing the immune response to adenovirus-mediated gene therapy. Gene Therapy 1996; 3: 154-162.
    • (1996) Gene Therapy , vol.3 , pp. 154-162
    • Kass-Eisler, A.1
  • 21
    • 0028346944 scopus 로고
    • A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity
    • Acsadi G et al. A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity. Hum Mol Gen 1994; 3: 579-584.
    • (1994) Hum Mol Gen , vol.3 , pp. 579-584
    • Acsadi, G.1
  • 22
    • 0028032357 scopus 로고
    • Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus
    • Tripathy SK et al. Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus. Proc Natl Acad Sci USA 1994; 91: 11557-11561.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11557-11561
    • Tripathy, S.K.1
  • 23
    • 0029916598 scopus 로고    scopus 로고
    • Successful expression of human factor IX following repeat administration of an adenoviral vector in mice
    • Walter J et al. Successful expression of human factor IX following repeat administration of an adenoviral vector in mice. Proc Natl Acad Sci USA 1996; 93: 3056-3061.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3056-3061
    • Walter, J.1
  • 24
    • 0011287921 scopus 로고
    • Lymphopoiesis
    • Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds). WB Saunders: Philadelphia
    • Haynes BF, Denning SM. Lymphopoiesis. In: Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds). The Molecular Basis of Blood Diseases, 2nd edn. WB Saunders: Philadelphia, 1994, pp 425-462.
    • (1994) The Molecular Basis of Blood Diseases, 2nd Edn. , pp. 425-462
    • Haynes, B.F.1    Denning, S.M.2
  • 25
    • 0022600536 scopus 로고
    • Thymocyte subpopulations during early fetal development in sheep
    • Mackay CR, Maddox JF, Brandon MR. Thymocyte subpopulations during early fetal development in sheep. J Immunol 1986; 136: 1592-1599.
    • (1986) J Immunol , vol.136 , pp. 1592-1599
    • Mackay, C.R.1    Maddox, J.F.2    Brandon, M.R.3
  • 26
    • 0028899135 scopus 로고
    • Early human T cell development: Analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment
    • Haynes BF, Heinly CS. Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment. J Exp Med 1995; 181: 1445-1458.
    • (1995) J Exp Med , vol.181 , pp. 1445-1458
    • Haynes, B.F.1    Heinly, C.S.2
  • 27
    • 78651149289 scopus 로고
    • Fetal response to antigenic stimulus IV. Rejection of skin homografts by the fetal lamb
    • Silverstein AM, Prendergast RA, Kraner KL. Fetal response to antigenic stimulus IV. Rejection of skin homografts by the fetal lamb. J Exp Med 1964; 119: 955-964.
    • (1964) J Exp Med , vol.119 , pp. 955-964
    • Silverstein, A.M.1    Prendergast, R.A.2    Kraner, K.L.3
  • 28
    • 0026717362 scopus 로고
    • Engraftment and long-term expression of human fetal hemapoietic stem cells in sheep following transplantation in utero
    • Zanjani ED et al. Engraftment and long-term expression of human fetal hemapoietic stem cells in sheep following transplantation in utero. J Clin Invest 1992; 89: 1178-1188.
    • (1992) J Clin Invest , vol.89 , pp. 1178-1188
    • Zanjani, E.D.1
  • 30
    • 0014481457 scopus 로고
    • Antibody responses to Brucella ovis in maternal and foetal sheep
    • Osburn BI, Hoskins RK. Antibody responses to Brucella ovis in maternal and foetal sheep. J Infect Dis 1969; 119: 267-272.
    • (1969) J Infect Dis , vol.119 , pp. 267-272
    • Osburn, B.I.1    Hoskins, R.K.2
  • 31
    • 0000173515 scopus 로고
    • Fetal response to antigenic stimulus. II. Antibody production by the fetal lamb
    • Silverstein AM, Uhr JW, Kraner KL. Fetal response to antigenic stimulus. II. Antibody production by the fetal lamb. J Exp Med 1963; 117: 799-812.
    • (1963) J Exp Med , vol.117 , pp. 799-812
    • Silverstein, A.M.1    Uhr, J.W.2    Kraner, K.L.3
  • 32
    • 0028834921 scopus 로고
    • In utero gene transfer into the pulmonary epithelium
    • Sekhon HS, Larson JE. In utero gene transfer into the pulmonary epithelium. Nature Med 1995; 1: 1201-1203.
    • (1995) Nature Med , vol.1 , pp. 1201-1203
    • Sekhon, H.S.1    Larson, J.E.2
  • 33
    • 0019393675 scopus 로고
    • Epithelial solute permeability, ion transport and tight junction morphology in the developing lung of the fetal lamb
    • Olver RE, Schneeburger EE, Walters DV. Epithelial solute permeability, ion transport and tight junction morphology in the developing lung of the fetal lamb. J Physiol 1981; 315: 395-412.
    • (1981) J Physiol , vol.315 , pp. 395-412
    • Olver, R.E.1    Schneeburger, E.E.2    Walters, D.V.3
  • 34
    • 0028979812 scopus 로고
    • Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells
    • Teramoto S et al. Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells. Hum Gene Ther 1995; 6: 1045-1053.
    • (1995) Hum Gene Ther , vol.6 , pp. 1045-1053
    • Teramoto, S.1
  • 35
    • 0029977465 scopus 로고    scopus 로고
    • Immediate inflammatory responses to adenovirus-mediated gene transfer in rat salivary glands
    • Adesanya MR, Redman RS, Baum BJ, O'Connell BC. Immediate inflammatory responses to adenovirus-mediated gene transfer in rat salivary glands. Hum Gene Ther 1996; 7: 1085-1093.
    • (1996) Hum Gene Ther , vol.7 , pp. 1085-1093
    • Adesanya, M.R.1    Redman, R.S.2    Baum, B.J.3    O'Connell, B.C.4
  • 36
    • 0029363066 scopus 로고
    • Complications of indwelling, silastic central venous access catheters in dogs and cats
    • Blaiset MA, Couto CG, Evans KL, Smeak DD. Complications of indwelling, silastic central venous access catheters in dogs and cats. J Am Animal Hosp Assoc 1995; 31: 379-384.
    • (1995) J Am Animal Hosp Assoc , vol.31 , pp. 379-384
    • Blaiset, M.A.1    Couto, C.G.2    Evans, K.L.3    Smeak, D.D.4
  • 37
    • 0024151643 scopus 로고
    • The ontogeny of the lymphoid system and immune responsiveness in sheep
    • Miyasaka M, Morris B. The ontogeny of the lymphoid system and immune responsiveness in sheep. Prog Vet Microbiol Immunol 1988; 4: 21-55.
    • (1988) Prog Vet Microbiol Immunol , vol.4 , pp. 21-55
    • Miyasaka, M.1    Morris, B.2
  • 38
    • 0021843906 scopus 로고
    • Pulmonary toxicity of monocrotaline differs at critical periods of lung development
    • Todd L, Mullen M, Olley PM, Rabinovitch M. Pulmonary toxicity of monocrotaline differs at critical periods of lung development. Pediatr Res 1985; 19: 731-737.
    • (1985) Pediatr Res , vol.19 , pp. 731-737
    • Todd, L.1    Mullen, M.2    Olley, P.M.3    Rabinovitch, M.4
  • 39
    • 0022348882 scopus 로고
    • Postnatal development of alveoli. Regulation and evidence for a critical period in rats
    • Massaro D et al. Postnatal development of alveoli. Regulation and evidence for a critical period in rats. J Clin Invest 1985; 76: 1297-1305.
    • (1985) J Clin Invest , vol.76 , pp. 1297-1305
    • Massaro, D.1
  • 40
    • 0025604698 scopus 로고
    • Late pulmonary sequelae of bronchopulmonary dysplasia
    • Northway WH et al. Late pulmonary sequelae of bronchopulmonary dysplasia. New Engl J Med 1990; 323: 1793-1799.
    • (1990) New Engl J Med , vol.323 , pp. 1793-1799
    • Northway, W.H.1
  • 41
    • 0026043883 scopus 로고
    • Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis
    • Trapnell BC et al. Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis. Proc Natl Acad Sci USA 1991; 88: 6565-6569.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6565-6569
    • Trapnell, B.C.1
  • 42
    • 0017858727 scopus 로고
    • Vero microcultures for adenovirus neutralization tests
    • Hierholzer J, Bingham P. Vero microcultures for adenovirus neutralization tests. J Clin Micro 1978; 7: 499-506.
    • (1978) J Clin Micro , vol.7 , pp. 499-506
    • Hierholzer, J.1    Bingham, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.