Active HIV-1 redistribution and replication in the brain with HIV encephalitis

Archives of Virology

Volumn 144, Issue 1, 1999, Pages 29-43

  Gatanaga, H ^a,b,c   Oka, S ^b   Ida, S ^b   Wakabayashi, T ^a   Shioda, T ^a   Iwamoto, A ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c AIDS Clinical Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG RESISTANCE; HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; VIRUS GENE; VIRUS INFECTION; VIRUS REPLICATION; ZIDOVUDINE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032921657     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007050050483     Document Type: Article

References (34)

1. 1. Van't Wout AB, Ran LJ, Kuiken CL, Kootstra NA, Pals ST, Schuitemaker H (1998) Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy. J Virol 72: 488-496
2. 2. Bagasra O, Lavi E, Bobroski L, Khalili K, Pestaner JP, Tawardros R, Pomerantz RJ (1996) Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by combination of in situ polymerase chain reaction and immunohistochemistry. AIDS 10: 573-585
3. 3. Böni J, Emmerich BS, Leib SL, Wiestler OD, Schüpbach J, Kleihues P (1993) PCR identification of HIV-1 DNA sequences in brain tissue of patients with AIDS encephalopathy. Neurology 43: 1813-1817
4. 4. Boucher CAB, O'Sullivan E, Mulder JW, Ramautarsing C, Kellam P, Darby G, Lange JMA, Goudsmit J, Larder BA (1992) Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus positive patients. J Infect Dis 165: 105-110
5. 5. Clelend A, Watson HG, Robertson P, Ludlam CA, Brown AJL (1996) Evolution of zidovudine resistance-associated genotypes in human immunodeficiency virus type 1-infected patients. J Acquir Immunne Defic Syndrome 12: 6-18
6. 6. Di Stefano M, Gray F, Leitner T, Chiodi F (1996) Analysis of ENV V3 sequences from HIV-1-infected brain indicates restrained virus expression throughout the disease. J Med Virol 49: 41-48
7. 7. Di Stefano M, Sabri F, Leitner T, Svennerholm B, Hagberg L, Norkrans G, Chiodi F (1995) Reverse transcriptase sequence of paired isolates of cerebrospinal fluid and blood from patients infected with human immunodeficiency virus type 1 during zidovudine treatment. J Clin Microbiol 33: 352-355
8. 8. Doranz BJ, Rucker J, Yi Y, Symth RJ, Samson M, Peiper SC, Paramentier M, Collman RG, Doms RW (1996) A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85: 1149-1158
9. 9. Epstein LG, Kuiken C, Bulmberg BM, Hartman S, Sharer LR, Clement M, Goudsmit J (1991) HIV-1 V3 domain variation in brain and spleen of children with AIDS' tissue-specific evolution within host-determined quasispecies. Virology 180: 583-590
10. 10. Gabuzda DH, Ho DD, De la Monte SM, Hirsch MS, Rota TR, Sobel RA (1986) Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann Neurol 20: 289-295
11. 11. Gartner S, Markovits P, Markovitz DM, Betts RF, Popovic M (1986) Virus isolation from and identification of HTLV-III/LAV producing cells in brain tissue from a patient with AIDS. JAMA 256: 2365-2371
12. 12. He J, Chen Y, Farzan M, Hyeryun C, Ohagen A, Gartner S, Busciglio J, Xiaoyu Y, Hofmann W, Newman W, Mackay CR, Sodroski J, Gabuzda D (1997) CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 385: 645-649
13. 13. Hwang SS, Boyle TJ, Lyefly HK, Cullen BR (1991) Identification of the envolpe V3 loop as the primary determinant of cell tropism in HIV-1. Science 253: 71-74
14. 14. Ida S, Gantanga H, Shioda T, Nagai Y, Kobayashi N, Shimada K, Kimura S, Iwamoto A, Oka S (1997) HIV type 1 V3 variation dynamics in vivo: Long-term persistence of non-syncytium-inducing genotypes and transient presence of syncytium-inducing genotypes during the course of progressive AIDS. AIDS Res Hum Retroviruses 13: 1597-1609
15. 15. Kellam P, Boucher CAB, Larder BA (1992) Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Proc Natl Acad Sci USA 89: 1934-1938
16. 16. Kellam P, Boucher CAB, Tijnagel JMGH, Larder BA (1992) Zidovudine treatment results in the selection of human immunodeficiency virus type 1 variants whose genotypes confer increasing levels of drug resistance. J Gen Virol 75: 341-351
17. 17. Koenig S, Gendelman HE, Orenstein JM, Dal Canto MC, Pezeshkpour GH, Yungbluth M, Janotta F, Aksamit A, Martin MA, Fauch AS (1986) Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233: 1089-1093
18. 18. Koot M, Vos AH, Keet RP, de Goede RE, Dercksen MW, Terpstra FG, Coutinho RA, Miedema E, Termette M (1992) HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay. AIDS 6: 49-54
19. 19. Korber BTM, Kunstman KJ, Patterson BK, Furtado M, McEvilly MM, Levy R, Wolinsky SM (1994) Genetic differences between blood-and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences. J Virol 68: 7467-7481
20. 20. Larder BA, Kemp SD (1989) Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 246: 1155-1158
21. 21. Maniatis T, Fritsch EF, Sambrook J (1982) Extraction, purification, and analysis of messenger RNA from eukaryotic cells. In: Irwin N (ed) Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, New York, pp 7.3-7.25
22. 22. Monken CE, Wu B, Srinivasan A (1995) High resolution analysis of HIV-1 quasispecies in brain. AIDS 9: 345-349
23. 23. Nájera I, Holguin A, Quifiñones-Mateu ME, Muñoz-Fernández MA, Nájera R, López-Galíndez C, Domingo E (1995) pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J Virol 69: 23-31
24. 24. Oka S, Ida S, Shioda T, Takebe Y, Kobayashi N, Shibuya Y, Ohyama K, Momota K, Kimura S, Shimada K (1994) Genetic analysis of HIV-1 during rapid progression to AIDS in apparently healthy man. AIDS Res Hum Retroviruses 10: 271-277
25. 25. Power C, McArthur JC, Johnson RT, Griffin DE, Glass JD, Perryman S, Chesebro B (1994) Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences. J Virol 68: 4643-4649
26. 26. Reddy RT, Achim CL, Sirko DA, Tehranchi S, Kraus FG, Wong-Staal F, Wiley CA, The HIV Neurobehavioral Research Group (1996) Sequence analysis of the V3 loop in brain and spleen of patients with HIV encephalitis. AIDS Res Hum Retroviruses 12: 477-482
27. 27. Schinazi RF, Lloyd Jr RM, Ramanathan CS, Taylor EW (1994) Antiviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase occur in specific RNA structural regions. Antimicrob Agents 38: 268-274
28. 28. Sheehy N, Desselberger U, Whitwell H, Ball JK (1996) Concurrent evolution of regions of the envelope and polymerase genes of human immunodeficiency virus type 1 observed during zidovudine (AZT) therapy. J Gen Virol 76: 1071-1081
29. 29. Sinclair E, Scaravilli F (1992) Detection of HIV proviral DNA in cortex and white matter of AIDS brains by non-isotopic polymerase chain reaction: correlation with diffuse poliodystrophy. AIDS 6: 925-932
30. 30. Vazeux R, Brousse N, Jarry A, Henin D, Marche C, Vedrenne C, Mikol J, Wolff M, Michon C, Rozenbaum W, Bureau J-F, Montagnier L, Brahic M (1987) AIDS subacute encephalitis' identification of HIV-infected cells. Am J Pathol 126: 403-411
31. 31. Watkins BA, Dom HH, Kelly WB, Armstrong RC, Potts BJ, Michaels F, Kufta CV, Dubois-Dalcq M (1990) Specific tropism of HIV-1 for microglial cells in primary human brain cultures. Science 249: 549-553
32. 32. Wildemann B, Hass J, Ehrhart K, Wagner H, Lynen N, Storch-Hagenlocher B (1993) In vivo comparison of zidovudine resistance mutations in blood and CSF of HIV-1-infected patients. Neurology 43: 2659-2663
33. 33. Wiley CA, Schrier RD, Nelson JA, Lampert PW, Oldstone MBA (1986) Cellular localization of human immunodeficiency virus infection within the brains of acquired immunodeficiency syndrome patients. Proc Natl Acad Sci USA 83: 7089-7097
34. 34. Wong JK, Ignacio CC, Torriani F, Havlir D, Fitch NJS, Richman DD (1997) In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues. J Virol 71: 2059-2071