Laser conization of cervical intraepithelial neoplasia grade 3: Free resection margins indicative of lesion-free survival

Acta Obstetricia et Gynecologica Scandinavica

Volumn 78, Issue 1, 1999, Pages 54-59

  Bertelsen, Bjoørn ^a,b   Tande, Tormod ^a   Sandvei, Roar ^a   Hartveit, Flora ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cervical intraepithelial neoplasia (CIN 3); Human papillomavirus (HPV); Laser conization; Recurrent disease; Resection margins

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; CANCER SURVIVAL; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LASER SURGERY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SURVIVAL TIME; TREATMENT FAILURE; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX CONIZATION; VIRUS INFECTION; WART VIRUS;

EID: 0032921654     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1080/j.1600-0412.1999.780112.x     Document Type: Article

References (42)

1. 1. Macgregor JE, Campbell MK, Mann EMF, Svvanson KY. Screening for cervical intraepithelial neoplasia in north east Scotland shows fall in incidence and mortality from invasive cancer with concomitant rise in preinvasive disease. BMJ 1994; 308: 1407-11.
2. 2. Kolstad P, Klem V. Long-term follow up of 1121 cases of carcinoma in situ. Obstet Gynecol 1976; 48: 125-9.
3. 3. Baldauf J-J, Dreyfus M, Ritter J, Philippe E. An analysis of the factors involved in the diagnostic accuracy of colposcopically directed biopsy. Acta Obstet Gynecol Scand 1997; 76: 468-73.
4. 2 laser. Am J Obstet Gynecol 1989; 161: 60-8.
5. 5. Ueki M, Kitsuki K, Misaki O, Seiki Y, Ueda M. Clinical evaluation of contact Nd-YAG laser conization for cervical intraepithelial neoplasia of the uterus. Acta Obstet Gynecol Scand 1992; 71: 465-70.
6. 2 laser excisional conization for cervical intraepithelial neoplasia under local anesthesia. Acta Obstet Gynecol Scand 1993; 72: 302-6.
7. 7. Bekassy Z, Ahlgren M, Eriksson M, Lindh E. Carbon dioxide laser miniconization for treatment of human papillomavirus infection associated with cervical intraepithelial neoplasia. Acta Obstet Gynecol Scand 1995; 74: 822-6.
8. 8. McIndoe GAJ, Robson MS, Tidy JA, Mason WP, Anderson MC. Laser excision rather than vaporization: The treatment of choice for cervical intraepithelial neoplasia. Obstet Gynecol 1989; 74: 165-8.
9. 9. Partington CK, Turner MJ, Soutter WP, Griffiths M, Krausz T. Laser vaporization versus laser excision conization in the treatment of cervical intraepithelial neoplasia. Obstet Gynecol 1989; 73: 775-8.
10. 10. Andersen ES, Pedersen B, Nielsen K. Laser conization: The results of treatment of cervical intraepithelial neoplasia. Gynecol Oncol 1994; 54: 201-4.
11. 11. Vedel P, Jakobsen H, Kryger-Baggesen N, Rank F, Bostofte E. Five-year follow up of patients with cervical intra-epithelial neoplasia in the cone margins after conization. Eur J Obstet Gynecol Reprod Biol 1993; 50: 71-6.
12. 12. Skjeldestad FE, Hagen B, Lie AK, Isaksen C. Residual and recurrent disease after laser conization for cervical intraepithelial neoplasia. Obstet Gynecol 1997; 90: 428-33.
13. 13. Schiffman MH, Bauer HM, Hoover RN, Glass AG, Cadell DM, Rush BB et al. Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst 1993; 85: 958-64.
14. 14. Crook T, Wrede D, Vousden KH. p53 point mutation in HPV negative human cervical carcinoma cell lines. Oncogene 1991; 6: 873-5.
15. 15. Riou G, Favre M, Jeannel D, Bourhis J, Le Doussal V, Orth G. Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA. Lancet 1990; 335: 1171-4.
16. 16. Oka K, Nakano T, Arai T. p53CM1 expression is not associated with prognosis in uterine cervical carcinoma. Cancer 1993; 72: 160-4.
17. 17. Dorsey JH, Diggs ES. Microsurgical conization of the cervix by carbon dioxide laser. Obstet Gynecol 1979; 54: 565-70.
18. 18. Koss LG. Epidermoid carcinoma of the uterine cervix and related precancerous lesions. In: Koss LG, ed. Diagnostic Cytology. 3rd ed. Philadelphia: Lippincott Company, 1979: 285-375.
19. 19. Coleman DV, Evans DMD. Biopsy pathology and cytology of the cervix. London: Chapman and Hall Medical, 1988.
20. 20. Vojtesek B, Bartek J, Midgley CA, Lane DP. An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53. J Immunol Methods 1992; 151: 237-44.
21. 21. Andersen ES, Nielsen K, Larsen G. Laser conization: Follow-up in patients with cervical intraepithelial neoplasia in the cone margins. Gynecol Oncol 1990; 39: 328-31.
22. 22. Vergote IB, Makar AP, Kjorstad KE. Laser excision of the transformation zone as treatment of cervical intraepithelial neoplasia with satisfactory colposcopy. Gynecol Oncol 1992; 44: 235-9.
23. 23. Lopes A, Morgan P, Murdoch J, Piura B, Monaghan JM. The case for conservative management of 'incomplete excision' of CIN after laser conization. Gynecol Oncol 1993; 49: 247-9.
24. 24. Urbaniak KJ, Widjaja A. Endocervical cell retrieval following excisional treatment of CIN. Acta Obstet Gynecol Scand 1996; 75: 63-7.
25. 25. Ostergard DR. Prediction of clearance of cervical intraepithelial neoplasia by conization. Obstet Gynecol 1980; 56: 77-80.
26. 26. White CD, Cooper WL, Williams RR. Cervical intraepithelial neoplasia extending to the margins of resection in conization of the cervix. J Reprod Med 1991; 36: 635-8.
27. 27. Burghardt E, Holzer E. Diagnosis and treatment of microinvasive carcinoma of the cervix uteri. Obstet Gynecol 1977; 49: 641-53.
28. 28. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Human papillomaviruses. Lyon: World Health Organization, 1995.
29. 29. Cuzick J, Terry G, Ho L, Hollingworth T, Anderson M. Type-specific human papillomavirus DNA in abnormal smears as a predictor of high-grade cervical intraepithelial neoplasia. Br J Cancer 1994; 69: 167-71.
30. 30. Bertelsen B, Kalvenes MB, Hartveit F. Human papillomavirus infection in progressive and non-progressive cervical intraepithelial neoplasia. APMIS 1996; 104: 900-6.
31. 31. Holm R, Skomedal H, Helland Å, Kristensen G, Boørresen A-L, Nesland JM. Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri. J Pathol 1993; 169: 21-6.
32. 32. Tervahauta AI, Syrjänen SM, Väyrynen M, Saastamoinen J, Syrjänen KJ. Expression of p53 protein related to the presence of human papillomavirus (HPV) DNA in genital carcinomas and precancer lesions. Anticancer Res 1993; 13: 1107-12.
33. 33. Inoue M, Fujita M, Enomoto T, Morimoto H, Monden T, Shimano T et al. Immunohistochemical analysis of p53 in gynecologic tumors. Am J Clin Pathol 1994; 102: 665-70.
34. 34. Amortegui AJ, Meyer MP, Elborne VL, Amin RM. p53, retinoblastoma gene product, and cyclin protein expression in human papillomavirus DNA-positive cervical intraepithelial neoplasia and invasive cancer. Mod Pathol 1995; 8: 907-12.
35. 35. Mittal KR, Lin O, Chan W, Goswami S, Demopoulos RI. Cervical squamous dysplasia and carcinomas with immunodetectable p53 frequently contain HPV. Gynecol Oncol 1995; 58: 289-94.
36. 36. Raju GC, Teh M, Wee A. An immunohistochemical study of p53 protein in cervical intraepithelial neoplasia and squamous cell carcinoma. Pathology 1996; 28: 17-19.
37. 37. Garzetti GG, Ciavattini A, Lucarini G, Goteri G, De Nictolis M, Fabris G et al. p53 immunostaining and HPV DNA detection by PCR in cervical intraepithelial neoplasia: clinical implications of a combined evaluation. Anticancer Res 1997; 17: 555-60.
38. 38. Helland Å, Holm R, Kristensen G, Kaern J, Karlsen F, Trope C et al. Genetic alterations of the tp53 gene, p53 protein expression and HPV infection in primary cervical carcinomas. J Pathol 1993; 171: 105-14.
39. 39. Paquette RL, Lee YY, Wilezynski SP, Karmakar A, Kizaki M, Miller CW et al. Mutations of p53 and human papillomavirus infection in cervical carcinoma. Cancer 1993; 72: 1272-80.
40. 40. Wistuba II, Montellano FD, Milchgrub S, Virmani AK, Behrens C, Chen H et al. Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma. Cancer Res 1997; 57: 3154-8.
41. 41. Busby-Earle RMC, Steel CM, Williams ARW, Cohen B, Bird CC. p53 mutations in cervical carcinogenesis - low frequency and lack of correlation with human papillomavirus status. Br J Cancer 1994; 69: 732-7.
42. 42. Dellas A, Schultheiss E, Almendral AC, Gudat F, Oberholzer M, Feichter G et al. Altered expression of mdm-2 and its association with p53 protein status, tumor-cell proliferation rate and prognosis in cervical neoplasia. Int J Cancer 1997; 74: 421-5.