A simple, nonenzymatic method for desialylating polysialylated ganglio- N-tetraose series gangliosides to produce GM1

Journal of Lipid Research

Volumn 40, Issue 1, 1999, Pages 160-163

  Schengrund, Cara Lynne ^a   Kováč, Pavol ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Dowex H+; Ganglioside GM1; Sialic acid

Indexed keywords

GANGLIOSIDE; GANGLIOSIDE GM1; SIALIC ACID;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; CATALYSIS; CATTLE; CHEMICAL PROCEDURES; CHOLESTEROL SYNTHESIS; HYDROLYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ASSAY; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANION EXCHANGE RESINS; BRAIN CHEMISTRY; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; G(M1) GANGLIOSIDE; GANGLIOSIDES; MAGNETIC RESONANCE SPECTROSCOPY; NEURAMINIDASE; OLIGOSACCHARIDES; RESINS, SYNTHETIC; SIALIC ACIDS; VIBRIO CHOLERAE;

EID: 0032921456     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Svennerholm, L. 1980. Ganglioside designation. Adv. Exp. Med. Biol. 125: 11.
2. Roisen, F. J., H. Bartfeld, R. Nagele, and G. Yorke. 1981. Ganglioside stimulation of axonal sprouting in vitro. Science. 214: 577-578.
3. Doherty, P., S. V. Ashton, S. D. Skaper, A. Leon, and F. S. Walsh. 1992. Ganglioside modulation of neural cell adhesion molecule and N-cadherin-dependent neunte outgrowth. J. Cell Biol. 117: 1093-1099.
4. Wang, L. J., R. Colella, G. Yorke, and F. J. Roisen. 1996. The ganglioside GM1 enhances microtubule networks and changes the morphology of Neuro-2a cells in vitro by altering the distribution of MAP2. Exp. Neurol. 139: 1-11.
5. Sachinidis, A., R. Kraus, C. Seul, M. K. Meyer Zu Brickwedde, K. Schulte, Y. Ko, J. Hoppe, and H. Vetter. 1996. Gangliosides GM1, GM2, and GM3 inhibit platelet-derived growth factor-induced signalling transduction pathway in vascular smooth muscle cells by different mechanisms. Eur. J. Cell Biol. 71: 79-88.
6. Fishman, P. H. 1982. Role of membrane gangliosides in the binding and action of bacterial toxins. J. Membr. Biol. 69: 85-97.
7. Superti, F., and G. Donelli. 1991. Gangliosides as binding sites in SA-11 rotavirus infection of LLC-MK2 cells. J. Gen. Virol. 72: 2467-2474.
8. Geisler, F. H., F. C. Dorsey, and W. P. Coleman. 1991. Recovery of motor functions alter spinal cord injury - a randomized placebo-controlled trial with GM1-ganglioside. N. Engf. J. Med. 324: 1829-1838.
9. Mohand-Said, S., M. Weber, D. Hicks, H. Dreyfus, and J. A. Sahel. 1997. Intravitreal injection of ganglioside GM1 after ischemia reduces retinal damage in rats. Stroke. 28: 617-622.
10. Mahoney, J. A., and R. L. Schnaar. 1994. Ganglioside-based neoglycoproteins. Methods Enzymol. 242: 17-27.
11. Thompson, J. P., and C-L. Schengrund. 1997. Oligosaccharidederivatized dendrimers: defined multivalent inhibitors of the adherence of the cholera toxin B subunit and the heat labile enterotoxin of E. coli to GMi. Glyconconj. J. 14: 837-845.
12. Moczar, E., and M. Moczar. 1967. The "fingerprinting" of the oligosaccharides derived from the partial hydrolysis of the glycoproteins of the connective tissues. Biochem. J. 104: 17p.
13. Kovac, P., F. Rendos, G. N. Persina, and E. Pavlovova. 1968. Hemicelluloses from twigs of the white willow (Salix alba L.) (III) Wood Xylans. Chem. Zvesti. 22: 198-205.
14. Folch, J., M. Lees, and G. H. Sloane Stanley. 1907. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 225: 497-509.
15. Ariga, T., and R. K. Yu. 1987. Isolation and characterization of ganglioside GM1b from normal human brain. J. Lipid Res. 28: 285-291.
16. Svennerholm, L. 1957. Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. Biochim. Biophys. Acta. 24: 604-611.
17. Ledeen, R. W., and R. K. Yu. 1982. Gangliosides: structure, isolation, and analysis. Methods Enzymol. 83: 139-191.
18. Ledeen, R., and K. Salsman. 1965. Structure of Tay-Sach's ganglioside. Biochemistry. 4: 2225-2232.
19. Lipovac, V., N. Barton, and A. Rosenberg. 1973. Control of the action of Vibrio cholerae sialidase on mammalian brain gangliosides by ionic strength. Biochemistry. 12: 1858-1861.
20. Warren, L. 1959. The thiobarbituric acid assay of sialic acids. J. Biol. Chem. 234: 1971-1975.
21. Koerner, Jr., T. A. W., J. H. Prestegard, P. C. Demou, and R. K. Yu. 1983. High-resolution proton NMR studies of gangliosides. 1. Use of homonurlear two-dimensional spin-echo J-correlated spectroscopy for determination of residue composition and anomeric configurations. Biochemistry. 22: 2676-2687.
22. Hasegawa, A., T. Nagahama, and M. Kiso. 1992. A facile, systematic synthesis of ganglio-series gangliosides: total synthesis of gangliosides GM1 and GD1a. Carbohydr. Res. 235: C13-C17.