Requirement for splenic CD4+ T cells in the immune privilege of the anterior chamber of the eye

Clinical and Experimental Immunology

Volumn 116, Issue 2, 1999, Pages 231-237

  Takahashi, M ^b   Ishimaru, N ^a   Yanagi, K ^a   Saegusa, K ^a   Haneji, N ^a   Shiota, H ^b   Hayashi, Yoshio ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b NONE

Author keywords

ACAID; CD4+ T cells; Cytokine mRNA; DTH; Tolerance

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 4;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR EYE CHAMBER; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTIC INFILTRATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTERIOR CHAMBER; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; FEMALE; HYPERSENSITIVITY, DELAYED; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; RNA, MESSENGER; SPLEEN; SPLENECTOMY;

EID: 0032919958     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00854.x     Document Type: Article

References (44)

1. 1 Kaplan H, Streilein JW. Immune response to immunization via the anterior chamber of the eye: I. F1-lymphocytes induced immune deviation. J Immunol 1977; 118:809-14.
2. 2 Barker CF, Billingham RE. Immunologically privileged sites. Adv Immunol 1977; 25:1-54.
3. 3 Streilein JW, Niederkorn JY, Shadduck JA. Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens. J Exp Med 1980; 152:1121-5.
4. 4 Niederkorn JY, Streilein JW, Shadduck JA. Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice. Invest Ophthalmol Vis Sci 1981; 20:355-63.
5. 5 Niederkorn JY, Streilein JW. Analysis of antibody production induced by allogeneic tumor cells inoculated into the anterior chamber of the eye. Transplantation 1982; 33:573-7.
6. 6 Ferguson TA, Waldep JC, Kaplan H. The immune response and the eye. II. The nature of T suppressor cell induction in anterior chamber-associated immune deviation (ACAID). J Immunol 1987; 139:352-7.
7. 7 Griffith TS, Herndon JM, Kahn M, Ferguson TA. The immune response and the eye: T cell receptor α-chain related molecules regulate the systemic immunity to antigen presented via the anterior chamber of the eye. Int Immunol 1995; 7:1617-25.
8. 8 Streilein JW, Atherton SS, Vann V. A critical role for ACAID in the distinctive pattern of retinitis that follows anterior chamber inoculation of HSV-1. Curr Eye Res 1987; 6:127-31.
9. 9 Wilbanks GA, Streilein JW. The differing patterns of antigen release and local retention following anterior chamber and intravenous inoculation of soluble antigen: evidence that the eye acts as an antigen depot. Reg Immunol 1989; 2:390-7.
10. 10 Streilein JW, Niederkorn JY. Induction of anterior chamber-associated immune deviation requires an intact, functional spleen. J Exp Med 1981; 153:1058-67.
11. 11 Wilbanks GA, Mammolenti M, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). III. Induction of ACAID depends upon intraocular transforming growth factor-γ. Eur J Immunol 1992; 22:165-73.
12. 12 Wilbanks GA, Streilein JW. Fluids from immune privileged sites endow macrophages with the capacity to induce antigen-specific immune deviation via a mechanism involving transforming growth factor-β. Eur J Immunol 1992; 22:1031-6.
13. 13 Maeda H, Shiraishi A. TGF-β contributes to the shift toward Th-2 type responses through direct and IL-10-mediated pathways in tumor-bearing mice. J Immunol 1996; 156:73-8.
14. 14 Talor AW, Alard P, Yee DG, Streilein JW. Aqueous humor induces transforming growth factor-β (TGF-β) -producing regulatory T-cells. Curr Eye Res 1997; 16:900-8.
15. 15 Griffith TS, Brenner T, Fletcher SM, Green DR, Ferguson TA. Fas ligand-induced apoptosis as a mechanism of immune privilege. Sci 1995; 270:1189-92.
16. 16 Griffith TS, Yu X, Herndon JM, Green DR, Ferguson TA. CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. Immunity 1996; 5:7-16.
17. 17 Niederkorn JY. Immune privilege and immune regulation in the eye. Adv Immunol 1990; 48:191-226.
18. 18 Niederkorn JY, Streilein JW. Induction of anterior chamber associated immune deviation (ACAID) by allogeneic intraocular tumor cells does not require splenic metastasis. J Immunol 1982; 128:2470-4.
19. 19 Wilbanks GA, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). I. Evidence that an antigen-specific, ACAID-indudng, cell-associated signal exists in the peripheral blood. J Immunol 1991; 146:2610-7.
20. 20 Niederkorn JY, Mayhew E. Role of splenic B cells in the immune privilege of the anterior chamber of the eye. Eur J Immunol 1995; 25:2783-7.
21. 21 Aberhsira-Amar O, Gibert M, Joliy M. Thëse J, Jankovic DL. IL-4 plays a dominant role in the differential development of Th0 into Th1 and Th2 cells. J Immunol 1992; 148:3820-9.
22. 22 Korp M, Gros GL, Bachmann M, Lamers MC, Bluethmann H, Köhler G. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993; 362:245-8.
23. 23 Garside P, Mowat AM. Polarization of Th-cell responses: a phylogenetic consequence of nonspecific immune defence? Immunol Today 1995; 16:220-3.
24. 24 Li X-Y, D'orazio T, Niederkorn JY. Role of Th1 and Th2 cells in anterior chamber-associated immune deviation. Immunol 1996; 89:34-40.
25. 25 Bando Y, Ksander BR, Streilein JW. Characterization of specific T helper cell activity in mice bearing alloantigenic tumors in the anterior chamber of the eye. Eur J Immunol 1991; 21:1923-31.
26. 26 Kosiewicz MM, Streilein JW. Intraocular injection of class II-restricted peptide induces an unexpected population of CD8 regulatory cells. J Immunol 1996; 157:1905-12.
27. 27 Talor AW, Streilein JW, Cousins SW. Immuno-reactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor. J Immunol 1994; 153:1080-6.
28. 28 Ferguson TA, Fletcher S, Herndon J, Griffith TS. Neuropeptides modulate immune deviation induced via the anterior chamber of the eye. J Immunol 1995; 155:1746-56.
29. 29 Talor AW, Streilein JW, Cousins SW. α-Melanocyte-stimulating hormone (α-MSH) suppresses immune-mediated inflammation. Neuroimmunomodulation 1994; 1:188-94.
30. 30 Talor AW, Streilein JW, Cousins SW. Vasoactive intestinal peptide (VIP) contributes to the immunosuppressive activity of normal aqueous humor. J Immunol 1994; 153:1080-6.
31. 31 Wilbanks GA, Mammolenti M, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating blood-home signals that induce ACAID. J Immunol 1991; 146:3018-24.
32. 32 Kinesely T, Anderson T, Sherwood ME, Flotte T, Albert D, Granstein RD. Morphologic and ultrastructural examination of 1-A+ cells in the murine iris. Invest Ophthal Vis Sci 1991; 32:2423-31.
33. 33 Williamson JSP, Bradley D, Streilein JW. Immunoregulatory properties of bone marrow-derived cells in the iris and ciliary body. Immunol 1989; 67:96-102.
34. 34 Streilein JW, Niederkorn JY. Characterization of the suppresser cell(s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells. J Immunol 1985; 134:1381-7.
35. 35 Wilbanks GA, Streilein JW. Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen. Evidence of two functionally and phenotypically distinct T-suppressor cell populations. Immunol 1990; 71:383-9.
36. 36 Ferguson TA, Hayashi JD, Kaplan H. The immune response and the eye. III. Anterior chamber-associated immune deviation can be adoptively transferred by serum. J Immunol 1989; 143:821-6.
37. 37 Egan RM, Yorkey C, Black R, Loh WK, Stevens JL, Woodward JG. Peptide-specific T cell clonal expansion in vivo following immunisation in the eye, an immune-privileged site. J Immunol 1996; 157:2267-71.
38. 38 Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of mouse helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-57.
39. 39 Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann Rev Immunol 1989; 7:145-73.
40. 40 Coffman RL, Mosmann TR. CD4+. T cell subsets: regulation of differentiation and function. Res Immunol 1991; 142:7-9.
41. 41 Mizuno K, Clark AF, Streilein JW. Anterior chamber associated immune deviation induced by soluble antigens. Invest Ophthalmol Vis Sci 1989; 30:1112-9.
42. 42 Benson JL, Niederkorn JY. The presence of donor-derived class II-positive cells abolishes immune privilege in the anterior chamber of the eye. Transplantation 1991; 51:34-38.
43. 43 Li L, Elliott JF, Mosmann TR. IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper cell-induced delayed-type hypersensitivity. J Immunol 1994; 153:3967-78.
44. 44 Ferguson TA, Dube P, Griffith TS. Regulation of contact hypersensitivity by interleukin-10. J Exp Med 1994; 179:1,597-604.