Podoplanin, a novel 43-kDa membrane protein, controls the shape of podocytes

Nephrology Dialysis Transplantation

Volumn 14, Issue SUPPL. 1, 1999, Pages 9-11

  Matsui, K ^b   Breiteneder Geleff, S ^b   Soleiman, A ^b   Kowalski, H ^b   Kerjaschki, Dontscho ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; MEMBRANE PROTEIN; PUROMYCIN AMINONUCLEOSIDE;

ANIMAL CELL; CELL SHAPE; CONFERENCE PAPER; GLOMERULOPATHY; NEPHROSIS; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEINURIA; RAT;

EID: 0032919513     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/14.suppl_1.9     Document Type: Conference Paper

References (14)

1. Breiteneder-Geleff S, Matsui K, Soleiman A, Meraner P, Poczewski H, Kalt R, Schaffner G, Kerjaschki D. Podoplanin, a novel 43-kd membrane protein of glomerular epithelial cells, is down regulated in puromycin nephrosis. Am J Pathol 1997; 151: 1141-1152
2. Rishi AK, Joyce-Brady M, Fisher J, Dobbs LG, Floros J, VanderSpek J, Brody JS, Williams MC. Cloning, characterization, and developmental expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives. Dev Biol 1995; 167: 294-230
3. Wetterwald A, Hofstetter W, Cecchini B, Lanske B, Wagner C, Fleisch H, Atkinson M. Characterization and cloning of the E1I antigen, a marker expressed by rat osteoblasts and osteocytes. Bone 1996; 18: 125-132
4. Nose K, Saito H, Kuroki T. Isolation of a gene sequence induced later by tumor-promoting 12-O-tetradecanoylphorbol-13-acetate in mouse osteoblastic cells (MC3T3-E1) and expressed constitutively in ras-transformed cells. Cell Growth Differ 1990; 1: 511-518
5. Farr A, Nelson A, Hosier S. Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus. J Histochem Cytochem 1992; 40: 651-664
6. Zimmer G, Klenk HD, Herrler G. Identification of a 40-kDa cell surface sialoglycoprotein with the characteristics of a major influenza C virus receptor in a Madin-Darby canine kidney cell line. J Biol Chem 1995; 270: 17815-17822
7. Kerjaschki D, Sharkey DJ, Farquhar MG. Identification and characterization of podocalyxin - the major sialoprotein of the renal glomerular epithelial cell. J Cell Biol 1984; 98: 1591-1596
8. Kerjaschki D, Vernillo AT, Farquhar MG. Reduced sialylation of podocalyxin - the major sialoprotein of the rat kidney glomerulus - in aminonucleoside nephrosis. Am J Pathol 1985; 118: 343-349
9. Matsui K, Breiteneder-Geleff S, Kerjaschki D. Epitope specific antibodies to the 43 kD glomerular membrane protein Podoplanin cause proteinuria and rapid flattening of podocytes. J Am Soc Nephrol in press
10. Kerjaschki D. Molecular pathogenesis of membranous nephropathy. Kidney Int 1992; 41: 1090-1105
11. Kerjaschki D, Neale TJ. Molecular mechanisms of glomcrular injury in rat experimental membranous ncphropathy (Heymann nephritis). J Am Soc Nephrol 1996; 7: 2518-2526
12. Majdic O, Stockl J, Pickl WF, Bohuslav J, Strobl H, Scheinecker C, Stockinger H, Knapp W. Signaling and induction of enhanced cytoadhesivencss via the hematopoietic progenitor cell surface molecule CD34. Blood 1994; 83: 1226-1234
13. Dantal J, Bigot E, Bogers W, Testa A, Kriaa F, Jacques Y, Hurault de Ligny B, Niaudet P, Charpentier B, Soulillou JP. Effect of plasma protein adsorption on protein excretion in kidney-transplant recipients with recurrent nephrotic syndrome. N Engl J Med 1994; 330: 7-14
14. Savin VJ, Sharma R, Sharma M, McCarthy ET, Swan SK, Ellis E, Lovell H, Warady B, Gunwar S, Chonko AM, Artero M, Vincenti F. Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerular sclerosis. N Engl J Med 1996; 334: 878-883