High-performance liquid chromatographic method for simultaneous determination of [1-methyl-14C]caffeine and its eight major metabolites in rat urine

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 726, Issue 1-2, 1999, Pages 195-201

  Schrader, Eberhard ^a   Klaunick, Götz ^a   Jorritsma, Ute ^a   Neurath, Hartmud ^a   Hirsch Ernst, Karen I ^a   Kahl, Georg F ^a   Foth, Heidi ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Caffeine; Cytochromes

Indexed keywords

BETA NAPHTHOFLAVONE; CAFFEINE; CARBON 14; DRUG METABOLITE; ETHOXYRESORUFIN DEETHYLASE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INDUCTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; ISOMERISM; ISOTOPE LABELING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TECHNIQUE; URINALYSIS;

ANIMALS; CAFFEINE; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; MALE; RATS; RATS, GUNN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032918191     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00040-7     Document Type: Article

References (25)

1. Nebert D.W., McKinnon R.A., Puga A. DNA Cell Biol. 15:1996;273.
2. Nebert D.W., Gonzalez F.J. Annu. Rev. Biochem. 56:1987;945.
3. Ostrow J.D., Kapitulnik J. Ostrow J.D. Bile Pigments and Jaundice. 1986;421 Marcel-Dekker, New York.
4. Berry C.S., Zarembo J.E., Ostrow J.D. Biochem. Biophys. Res. Commun. 49:1972;1366.
5. Kapitulnik J.D., Ostrow J.D. Proc. Natl. Acad. Sci. USA. 75:1978;682.
6. Cohen A.N., Kapitulnik J., Ostrow J.D., Webster C.C. Hepatology. 6:1986;490.
7. Kapitulnik J., Hardwick J.P., Ostrow J.D., Webster C.C., Park S.S., Gelboin H.V. Biochem. J. 242:1987;297.
8. Schmid R., Hammaker L. J. Clin. Invest. 42:1963;1720-1734.
9. Kalow W., Tang B.-K. Clin. Pharmacol. Ther. 53:1993;503.
10. Fuhr U., Doehmer J., Battula N., et al. Toxicology. 82:1993;169.
11. Fuhr U., Rost K.L., Engelhardt R., et al. Pharmacogenetics. 6:1996;159.
12. Fuhr U., Doehmer J., Battula N., et al. Biochem. Pharmacol. 43:1992;225.
13. Gu L., Gonzalez F.J., Kalow W., Tang B.K. Pharmacogenetics. 2:1992;73.
14. Arnaud M.J. v.Dews P.B. Caffeine, Perspectives from Recent Research. 1984;3 Springer, Berlin.
15. Arnaud M.J. Experientia. 32:1976;1238.
16. Arnaud M.J. Drug. Metab. Dispos. 13:1985;471.
17. Bienvenu T., Pons G., Rey E., Thiroux G., Olive G. Eur. J. Drug. Metab. Pharmacokinet. 18:1993;181.
18. Bonati M., Grattini S. v.Dews P.B. Caffeine, Perspectives from Recent Research. 1984;317 Springer, Berlin.
19. Arnaud M.J. Biochem. Med. 16:1976;67.
20. Christensen H.D., Neims A.H. v.Dews P.B. Caffeine, Perspectives from Recent Research. 1984;317 Springer, Berlin.
21. Scott N.R., Chakraborty J., Marks V. J. Chromatogr. 375:1986;321.
22. Leakey T.E. J. Chromatogr. 507:1990;199.
23. Tanaka E. J. Chromatogr. 575:1992;311.
24. Dobrocky P., Bennett P.N., Notarianni L.J. J. Chromatogr. 652:(1):1994;104.
25. Soucek P., Gut I. Xenobiotica. 22:1992;83.