Apoptotic index as a prognostic factor in Hodgkin's disease

Leukemia and Lymphoma

Volumn 33, Issue 3-4, 1999, Pages 351-359

  Benharroch, Daniel ^a   Levy, Amalia ^a   Prinsloo, Isebrand ^a   Ariad, Samuel ^a   Rabinovitch, Daniella ^a   Shendler, Yaakov ^a   Sacks, Martin ^a   Gopas, Jacob ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Apoptosis; Apoptotic index; Hodgkin's disease; Prognostic factors

Indexed keywords

ANTIBODY; DNA FRAGMENT; REAGENT;

ADULT; ANALYTICAL EQUIPMENT; APOPTOSIS; ARTICLE; CANCER STAGING; CANCER SURVIVAL; FEMALE; HODGKIN DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; REED STERNBERG CELL; RETROSPECTIVE STUDY; STATISTICAL ANALYSIS;

EID: 0032917445     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199909058435     Document Type: Article

References (27)

1. Arends, M.J., McGregor, A..H. and Wyllie, A.H. (1994) Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras and HPV oncogenes. American Journal of Pathology, 144, 1045-1057.
2. Spina D., Leoncini, L., Close, P., Megha, T., Pacenti, L., Tosi, P., Pileri, S., Sabattini, E., Kraft, R., Laissue, J.A. and Cottier, H. (1996) Growth vs. DNA strand breaks in Hodgkin's disease: impaired proliferative ability of Hodgkin and Reed-Sternberg cells. International Journal of Cancer, 66, 179-183.
3. Gerdes, J., van Baarlen, J., Pileri, S., Schwarting, R., van Unnik, J.A.M. and Stein, H. (1987) Tumor cell growth fraction in Hodgkin's disease. American Journal of Pathology, 128, 390-393.
4. Freeman, J., Kellock, D.B., Yu, C. C-W., Crocker, J., Levison, D.A. and Hall, P.A. (1993) Proliferating cell nuclear antigen (PCNA) and nucleolar organiser regions in Hodgkin's disease: correlation with morphology. Journal of Clinical Pathology, 46, 446-449.
5. Leoncini, L., Spina, D., Close, P., Megha, T., Pacenti, L., Tosi, P., Pileri, S., De Vivo, A., Kraft, R., Laissue, J.A. and Cottier, H. (1996) Abortive mitoses and nuclear DNA fragmentation in CD30+ large cells of Hodgkin's disease. Leukemia and Lymphoma, 22, 119-124.
6. Gupta, R.K., Lister, T.A. and Bodmer, J.G. (1994) Proliferation of Reed-Sternberg cells and variants in Hodgkin's disease. Annals of Oncology, 5, S117-S119.
7. Benharroch, D., Prinsloo, I., Goldstein, J., Brousset, P., Kachko, L. and Gopas, J. (1996) A comparison of distinct modes of tumor cell death in Hodgkin's disease using morphology and in situ DNA fragmentation. Ultrastructural Pathology, 20, 497-505.
8. Czader, M., Porwit, A., Ost, A. and Auer, G. (1994) DNA content and expression of PCNA and p53 in Hodgkin's disease and Hodgkin's-like B-cell lymphoma. APMIS, 102, 865-873.
9. Faguet, G.B. (1995) Hodgkin's disease: basing treatment decisions on prognostic factors. Leukemia and Lymphoma, 17, 223-228.
10. Leoncini, L., Del Vecchio, M.T., Megha, T., Barbini, P., Galieni, P., Pileri, S., Sabattini, E., Gherlinzoni, F., Tosi, P., Kraft, R. and Cottier, H. (1993) Correlations between apoptotic and proliferative indices in malignant non-Hodgkin's lymphomas. American Journal of Pathology, 142, 755-763.
11. Heatley, M.K. (1995) Association between the apoptotic index and established prognostic parameters in endometrial adenocarcinoma. Histopathology, 27, 469-472.
12. Kiberu, S.W., Pringle, J.H., Sobolewski, S., Murphy, P. and Lauder, I. (1996) Correlation between apoptosis, proliferation and bcl-2 expression in malignant non-Hodgkin's lymphoma. Journal of Clinical Pathology: Mol Pathol, 49, M268-M272.
13. Schellong, G., Riepenhausen, M., Creutzig, U., Ritter, J., Harbott, J., Mann, G. and Gadner, H. for the German-Austrian Pediatric Hodgkin's disease Group. (1997) Low risk of secondary leukemias after chemotherapy without Mechlorethamine in childhood Hodgkin's disease. Journal of Clinical Oncology, 15, 2247-2253.
14. Hsu, S.M., Raine, L. and Fanger, H. (1981) Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase technique. Journal of Histochemistry and Cytochemistry 29, 577-580.
15. Cox, D.R. (1972) Regression models and life tables. Journal of Royal Statistics Society Ser (B), 34, 187-220.
16. Lorenzen, J., Alavaikko, M. and Hansmann, M.L. (1995) Apoptosis in Hodgkin's disease. Pathologe, 16, 208-216.
17. Hell, K., Lorenzen, J., Hansmann, M.L., Fellbaum, C., Busch, R. and Fischer, R. (1993) Expression of the proliferating cell nuclear antigen in the different types of Hodgkin's disease. American Journal of Clinical Pathology, 99, 598-603.
18. Kaczorowski, S., Kaczorowska, M. and Christensson, B. (1994) Expression of EBV encoded latent membrane protein 1 (LMP-1) and bcl-2 protein in childhood and adult Hodgkin's disease: application of microwave irradiation for antigen retrival. Leukemia and Lymphoma, 13, 273-283.
19. Krueger, G.R.F., Guenther, A., Knuefermann, R., Kluppelberg, U., Luka, J., Pearson, G.R., Ablashi, D.V., Juecker, M. and Tesch, H. (1994) Human Herpesvirus-6 (HHV-6) in Hodgkin's disesase: Cellular expression of viral antigens as compared to oncogenes met and fes, tumor suppressor gene product p53, and interleukins 2 and 6. in vivo, 8, 501-516.
20. Wellman, A., Krenacs, L., Fest, T., Scherf, U., Pastan, I., Raffeld, M. and Brinkmann, U. (1997) Localization of the cell proliferation and apoptosis-associated CAS protein in lymphoid neoplasms. American Journal of Pathology, 150, 25-30.
21. Aihara, M., Scardino, P.T., Truong, L.D., Wheeler, T.M., Goad, J.R., Yang, G. and Thompson, T.C. (1994) The frequency of apoptosis correlates with prognosis of Gleason grade 3 adenocarcinoma of the prostate. Cancer 75, 522-529.
22. Levine EL, Davidson SE, Roberts SA, Chadwick CA, Potten CS, West CM. (1994) Apoptosis as predictor of response to radiotherapy in cervical carcinoma. The Lancet, 344, 472.
23. Lipponen, P.K. and Aaltomaa, S. (1994) Apoptosis in bladder cancer as related to standard prognostic factors and prognosis. Journal of Pathology, 173, 333-339.
24. Hall, P.A. and Coates, P.J. (1995) Assessment of cell proliferation in pathology - what next? Histopathology, 26, 105-112.
25. Benharroch, D., Prinsloo, I., Apte, R.N., Yermiahu, T., Geffen, D.B., Yanai-Inbar, I. And Gopas, J. (1996) Interleukin-1 and tumor necrosis factor-alpha in Reed-Sternberg cells of Hodgkin's disease. Correlation with clinical and morphological « inflammatory » features. European Cytokine Network, 7, 51-56.
26. Haecker, G. and Vaux, D.L. (1994) Viral, worm and radical implications for apoptosis. Trends in Biochemical Sciences, 19, 99-100.
27. Sheu, L-F., Chen, A., Wei, Y-H., Ho, K-C., Cheng, J-Y., Meng, C-L. and Lee, W-H. (1998) Epstein-Barr virus LMP1 modulates the malignant potential of gastric carcinoma cells involving apoptosis. American Journal of Pathology, 152, 63-74.