Synthesis and evaluation of 6-[11C]methoxy-3-[2[1-(phenylmethyl)-4- piperidinyl]ethyl]-1,2-benzisoxazole as an in vivo radioligand for acetylcholinesterase

Nuclear Medicine and Biology

Volumn 26, Issue 1, 1999, Pages 99-103

  Brown Proctor, Clive ^a   Snyder, Scott E ^a   Sherman, Phillip S ^a   Kilbourn, Michael R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Acetylcholinesterase; Carbon 11; Emission computed tomography

Indexed keywords

6 METHOXY 3 [2 [1 (PHENYLMETHYL) 4 PIPERIDINYL]ETHYL] 1,2 BENZISOXAZOLE; ACETYLCHOLINESTERASE; CARBON 11; ISOXAZOLE DERIVATIVE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; DRUG EFFECT; DRUG PENETRATION; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; MOUSE; NONHUMAN; TISSUE DISTRIBUTION;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; ANIMALS; BRAIN; CARBON RADIOISOTOPES; FEMALE; ISOXAZOLES; MACACA NEMESTRINA; MICE; PIPERIDINES; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032916931     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(98)00078-X     Document Type: Article

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