A mutation in the flanking 5'-TA-3' dinucleotide prevents excision of an internal eliminated sequence from the Paramecium tetraurelia genome

Genetics

Volumn 151, Issue 2, 1999, Pages 597-694

  Mayer, Kimberly M ^a   Forney, James D ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOTIDE;

ARTICLE; GENE DELETION; GENE MUTATION; GENE SEGREGATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARAMECIUM TETRAURELIA; PRIORITY JOURNAL; TRANSPOSON;

ANIMALS; ANTIGENS, PROTOZOAN; BASE SEQUENCE; GENOME, PROTOZOAN; MOLECULAR SEQUENCE DATA; MUTATION; PARAMECIUM TETRAURELIA; SEQUENCE ANALYSIS, DNA;

MYXOZOA; PARAMECIUM; PARAMECIUM TETRAURELIA; PROTOZOA;

EID: 0032915507     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. BAIRD, S. E., G. M. FINO, S. L. TAUSTS and L. A. KLOBUTCHER, 1989 Micronuclear genome organization is Euplotes crassus: a transposonlike element is removed during macronuclear development. Mol. Cell. Biol. 9: 3793-3807.
2. BRYAN, G., D. GARZA and D. HARTL, 1990 Insertion and excision of the transposable element mariner in Drosophila. Genetics 125: 103-114.
3. COYNE, R. S., D. L. CHALKER and M.-C. YAO, 1996 Genome downsizing during ciliate development: nuclear division of labor through chromosome restructuring. Annu. Rev. Genet. 30: 557-578.
4. DUBRANA, K., A. LE MOUEL and L. AMAR, 1997 Deletion endpoint allele-specificity in the developmentally regulated elimination of an internal sequence (IES) in Paramecium. Nucleic Acids Res. 25: 2448-2454.
5. DUHARCOURT, S., A.-M. KELLER and E. MEYER, 1998 Homology-dependent maternal inhibition of developmental excision of Internal Eliminated Sequences in Paramecium tetraurelia. Mol. Cell. Biol. 18: 7075-7085.
6. EPSTEIN, L. M., and J. D. FORNEY. 1984 Mendelian and non-Mendelian mutations affecting surface antigen expression in Paramecium tetraurelia. Mol. Cell. Biol. 4: 1583-1590.
7. FORNEY, J. D., and E. H. BLACKBURN, 1988 Developmentally controlled telomere addition in wild type and mutant paramecia. Mol. Cell. Biol. 8: 251-258.
8. GODISKA, R., C. JAMES and M.-C. YAO, 1993 A distant 10 bp sequence specifies the boundaries of a programmed DNA deletion in Tetrahymena. Genes Dev. 7: 2357-2365.
9. HARTL, D. L., A. R. LOHE and E. R. LOZOVSKAYA, 1997 Modern thoughts on an ancyent marinere: function, evolution, regulation. Annu. Rev. Genet. 31: 337-358.
10. JACOBS, M. E., and L. A. KLOBUTCHER, 1996 The long and the short of developmental DNA delection in Euplotes crassus. J. Eukaryot. Microbiol. 43: 442-452.
11. JAHN, C. L., S. Z. DOKTOR, J. S. FRELS, J. W. JARACZEWSKI and M. F. KRIKAU, 1993 Structures of the Euplotes crassus Tec1 and Tec2 elements: identification of putative transposase coding regions. Gene 133: 71-78.
12. JARACZEWSKI, J. W., J. S. FRELS and C. L. JAHN, 1994 Developmentally-regulated, low abundance Tec element transcripts in Euplotes crassus: implications for DNA elimination and transposition. Nuclei Acids Res. 22: 4535-4542.
13. KLOBUTCHER, L. A., and G. HERRICK, 1995 Consensus inverted terminal repeat sequence of Paramecium IESs: resemblance to termini of Tcl-related and Euplotes Tec transposons. Nucleic Acids Res. 23: 2006-2013.
14. KLOBUTCHER, L. A., and G. HERRICK, 1997 Developmental genome reorganization in ciliated Protozoa: the transposon link. Prog. Nucleic Acid Res. 56: 1-62.
15. KLOBUTCHER, L. A., and C. JAHN, 1991 Developmentally controlled genomic rearrangements in ciliated protozoa. Curr. Opin. Genet. Dev. 1: 397-403.
16. KRIKAU, M. F., and C. L. JAHN, 1991 Tec2, a second transposon-like element demonstrating developmentally programmed excision in Euplotes crassus. Mol. Cell. Biol. 11: 4751-4759.
17. LOHE, A. R., and D. L. HARTL, 1996 Reduced germline mobility of a marinervector containing exogenous DNA: effect of size or site? Genetics 143: 1299-1306.
18. MAYER, K. M., K. MIKAMI and J. D. FORNEY, 1998 A mutation in Paramecium tetraurelia reveals functional and structural features of developmentally excised DNA elements. Genetics 148: 139-149.
19. PLASTERK, R. H. A., 1996 The Tc1/mariner transposon family, pp. 125-143 in Transposable Elements, edited by H. SAEDLER and A. GIERL, Springer-Verlag, Berlin.
20. PRESCOTT, D. M., 1994 The DNA of ciliated Protozoa. Microbiol. Rev. 58: 223-267.
21. ROBERTSON, H. M., 1995 The Tcl-mariner superfamily of transposons in animals. J. Insect Physiol. 41: 99-105.
22. RUDMAN, B., L. B. PREER, B. POLISKY and J. R. PREER, JR., 1991 Mutants affecting processing of DNA in macronuclear development in Paramecium. Genetics 129: 47-55.
23. SAMBROOK, J., E. F. FRITSCH and T. MANIATIS, 1989 Molecular Cloning: A Laboratory Manual. Ed. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. SONNEBORN, T. M., 1970 Methods in Paramecium research, pp. 242-339 in Methods in Cell Physiology, Vol. 4, edited by D. M. PRESCOTT, Academic Press, New York.
25. SONNEBORN, T. M., and M. V. SCHNELLER, 1979 A genetic system for alternative stable characteristics in genomically identical homozygous clones. Dev. Genet. 1: 21-46.
26. STEELE, C. J., G. A. BARKOCY-GALLAGHER, L. B. PREER and J. R. PREER, JR., 1994 Developmentally excised sequences in micronuclear DNA of Paramecium. Proc. Natl. Acad. Sci. USA 91: 2255-2259.
27. VAN LUENEN, H. G. A. M., S. D. COLLOMS and R. H. A. PLASTERK, 1994 The mechanism of transposition of Tc3 in C. elegans. Cell 79: 293-301.
28. VAN POUDEROYEN, G. R. F. KETTING, A. PERRAKIS, R. H. A. PLASTERK and T. K. SIXMA, 1997 Crystal structure of the specific DNA-binding domain of Tc3 transposase of C. elegans in complex with transposon DNA. EMBO J. 16: 6044-6054.
29. VAYSSIE, L., L. SPERLING and L. MADEDDU, 1997 Characterization of multigene families in the micronuclear genome of Paramecium tetraurelia reveals a germline specific sequence in an intron of a centrin gene. Nucleic Acids Res. 25: 1035-1041.
30. VOS, J. C., I. D. BAERE and R. H. A. PLASTERK, 1996 Transposase is the only nematode protein required for in vitro transposition of Tcl. Genes Dev. 10: 755-761.