Effect of tumor necrosis factor-α on insulin signal transduction in rat adipocytes: Relation to PKCβ and ζ translocation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1449, Issue 3, 1999, Pages 227-238

  Miura, Atsushi ^a   Ishizuka, Tatsuo ^a   Kanoh, Yoshinori ^a   Ishizawa, Masayoshi ^a   Itaya, Satomi ^a   Kimura, Mika ^a   Kajita, Kazuo ^a   Yasuda, Keigo ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

12 O Tetradecanoyl phorbol 13 acetate; Insulin; Insulin resistance; Protein kinase C; Tumor necrosis factor

Indexed keywords

INSULIN; INSULIN I 125; INSULIN RECEPTOR SUBSTRATE 1; ISOENZYME; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG INHIBITION; ENZYME ACTIVATION; GLUCOSE TRANSPORT; INSULIN BINDING; INSULIN RESISTANCE; INTRACELLULAR TRANSPORT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SIGNAL TRANSDUCTION;

ADIPOCYTES; ANIMALS; CELL MEMBRANE; CYTOSOL; GLUCOSE; INSULIN; INSULIN RESISTANCE; ISOENZYMES; MALE; PHOSPHOPROTEINS; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; RATS; RATS, WISTAR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032915481     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(99)00016-6     Document Type: Article

References (46)

1. Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature. 334:1988;661-665.
2. Ishizuka T., Yamamoto M., Kajita K., Nagashima T., Yasuda K., Miura K., Cooper D.R., Farese R.V. Insulin stimulates novel protein kinase C in rat adipocytes. Biochem. Biophys. Res. Commun. 183:1992;814-820.
3. Ishizuka T., Yamamoto M., Kajita K., Nagashima T., Taniguchi O., Wada H., Itaya S., Yasuda K. Phorbol ester and insulin stimulate protein kinase C isoforms in rat adipocytes. Diabetes Res. Clin. Pract. 26:1994;91-99.
4. Ishizuka T., Nagashima T., Yamamoto M., Wada H., Itaya S., Yamada K., Miura A., Kanoh Y., Ishizawa M., Yasuda K. Acute effects of phorbol ester and insulin on insulin-induced glucose uptake and protein kinase C activation in rat adipocytes. Diabetes Res. Clin. Pract. 37:1997;49-52.
5. Ishizuka T., Cooper D.R., Farese R.V. Insulin stimulates translocation of protein kinase C in rat adipocytes. FEBS Lett. 257:1989;337-340.
6. Egan J.J., Saltis J., Wek S.A., Simpson I.A., Londos C. Insulin, oxytosin, and vasopressin stimulate protein kinase C activity in adipocyte plasma membranes. Proc. Natl. Acad. Sci. USA. 87:1990;1052-1056.
7. Ishizuka T., Cooper D.R., Hernandez H., Buckley D., Standaert M., Farese R.V. Effect of insulin on diacylglycerol-protein kinase C signaling in rat diaphragm and soleus muscles and relationship to glucose transport. Diabetes. 39:1990;181-190.
8. Ishizuka T., Cooper D.R., Arnold T., Hernandez H., Farese R.V. Downregulation of protein kinase C and insulin-stimulated 2-deoxyglucose uptake in rat adipocytes by phorbol ester, glucose, and insulin. Diabetes. 40:1991;1274-1281.
9. Standaert M., Buckley D.J., Ishizuka T., Hoffman J.M., Cooper D.R., Pollet R.J., Farese R.V. Protein kinase C inhibitors block insulin and PMA-stimulated hexose transport in isolated rat adipocytes BC3H-1 myocytes. Metabolism. 11:1990;1170-1179.
10. Robertson D.G., DiGirolamo M., Merrill A.H. Jr., Lambeth J.D. Insulin-stimulated hexose transport and glucose oxidation in rat adipocytes is inhibited by sphingosine at a step after insulin binding. J. Biol. Chem. 264:1989;6773-6779.
11. Hotamisligil G.S., Spiegelman B.M. Tumor necrosis factor α: A key component of the obesity-diabetes link. Diabetes. 43:1994;1271-1278.
12. Hotamisligil G.S., Shargill N.S., Spiegelman B.M. Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance. Science. 259:1993;87-91.
13. Hotamisligil G.S., Murray D.L., Choy L.N., Spiegelman B.M. Tumor necrosis factor α inhibits signaling from the insulin receptor. Proc. Natl. Acad. Sci. USA. 91:1994;4854-4858.
14. Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J. Clin. Invest. 95:1995;2409-2415.
15. Stephens J.M., Pekala P.H. Transcriptional repression of the GLUT4 and C/EBP Genes in 3T3-L1 adipocytes by tumor necrosis factor-α J. Biol. Chem. 266:1991;21839-21845.
16. Cornelius P., Lee M.D., Marlowe M., Pekala P.H. Monokine regulation of glucose transporter mRNA in L6 myotubes. Biochem. Biophys. Res. Commun. 165:1989;429-436.
17. Stephens J.M., Lee J., Pilch P.F. Tumor necrosis factor-α-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction. J. Biol. Chem. 272:1997;971-976.
18. Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance. Science. 271:1996;665-668.
19. Kanety H., Feinstein R., Papa M.Z., Hemi R., Karasik A. Tumor necrosis factor α-induced phosphorylation of insulin receptor substrate-1 (IRS-1). J. Biol. Chem. 270:1995;23780-23784.
20. Rodbell M. Metabolism of isolated fat cells. J. Biol. Chem. 239:1964;375-380.
21. Olefsky J.M. Mechanisms of the ability of insulin to activate the glucose-transport system in rat adipocytes. Biochem. J. 172:1978;137-145.
22. Olefsky J.M., Jen P., Reaven G.M. Insulin binding to isolated human adipocytes. Diabetes. 23:1974;565-571.
23. Wang C., O'Brien L., Brindley D.N. Effects of cell-permeable ceramide and tumor necrosis factor-α on insulin signaling and glucose uptake in 3T3-L1 adipocytes. Diabetes. 47:1998;24-31.
24. Farese R.V., Cooper D.R., Konda T.S., Nair G.P., Standaert M.L., Davis J.S., Pollet R.J. Mechanism whereby insulin increases diacylglycerol in BC3H-1 myocytes. Biochem. J. 256:1988;175-184.
25. Saltiel A.R., Fox J.A., Sherline P., Cuatrecasas P. Insulin- stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. Science. 233:1986;967-971.
26. Witters L.A., Vater C.A., Lienhard G.E. Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase C. Nature. 315:1985;777-778.
27. Standaert M.L., Bandyopadhyay G., Galloway L., Farese R.V. Effects of phorbol esters on insulin-induced activation of phosphatidylinositol 3-kinase, glucose transport, and glycogen synthase in rat adipocytes. FEBS Lett. 388:1996;26-28.
28. Martiny-Baron G., Kazanietz M.G., Mischak H., Blumberg P.M., Kochs G., Hug H., Marme D., Schachtele C. Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J. Biol. Chem. 268:1993;9194-9197.
29. Gschwendt M., Dieterich S., Rennecke J., Kittstein W., Mueller H.J., Johannes F.J. Inhibition of protein kinase C μ by various inhibitor. Differentiation from protein kinase C isozymes. FEBS Lett. 392:1996;77-80.
30. Chalfant C.E., Mischak H., Watson J.E., Winkler B.C., Goodnight J., Farese R.V., Cooper D.R. Regulation of alternative splicing of protein kinase Cβ by insulin. J. Biol. Chem. 270:1995;13326-13332.
31. Dressler K.A., Mathias S., Kolesnick R.N. Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell- free system. Science. 255:1992;1715-1718.
32. Peraldi P., Hotamisligil G.S., Buurman W.A., White M.F., Spiegelman B.M. Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J. Biol. Chem. 271:1996;13018-13022.
33. Obeid L.M., Linardic C.M., Karolak L.A., Hannun Y.A. Programmed cell death induced by ceramide. Science. 259:1993;1769-1771.
34. Jones M.J., Murray A.W. Evidence that ceramide selectively inhibits protein kinase C-α translocation and modulates bradykinin activation of phospholipase D. J. Biol. Chem. 270:1995;5007-5013.
35. Nakamura Y., Nakashima S., Ojio K., Banno Y., Miyata H., Nozawa Y. Ceramide inhibits IgE-mediated activation of phospholipase D, but not of phospholipase C, in rat basophilic leukemia (RBL-2H3) cells. J. Immunol. 156:1996;256-262.
36. Abousalham A., Liossis C., O'Brien L., Brindley N. Cell-permeable ceramide prevent the activation of phospholipase D by ADP-ribosylation factor and RhoA. J. Biol. Chem. 272:1997;1069-1075.
37. Sawai H., Okazaki T., Takeda Y., Tashima M., Sawada H., Okuma M., Kishi S., Umehara H., Domae N. Ceramide-induced translocation of protein kinase C-δ and -ε to the cytosol. J. Biol. Chem. 272:1997;2452-2458.
38. Standaert M.L., Galloway L., Karnam P., Bandyopadhyay G., Moscat J., Farese R.V. Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. J. Biol. Chem. 272:1997;30075-30082.
39. Bandyopadhyay G., Standaert M.L., Galloway L., Moscat J., Farese R.V. Evidence for involvement of protein kinase C (PKC)-ζ and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology. 138:1997;4721-4731.
40. Feinstein R., Kanety H., Papa M.Z., Lunenfeld B., Karasik A. Tumor necrosis factor-α suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrate. J. Biol. Chem. 268:1993;26055-26058.
41. Hotamisligil G.S., Budavari A., Murray D., Spiegelman B.M. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. J. Clin. Invest. 94:1994;1543-1549.
42. Müller G., Ayoub M., Storz P., Rennecke J., Fabbro D., Pfzenmaier K. PKCζ is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 14:1995;1961-1969.
43. Galve-Roperh I., Haro A., Díaz-Laviada I. Ceramide-induced translocation of protein kinase Cζ in primary cultures of astrocytes. FEBS Lett. 415:1997;271-274.
44. Blitterswijk W.J. Ceramide conditionally activates atypical protein kinase C, Raf-1 and KSR through binding to their cysteine-rich domains. Biochem. J. 331:1998;679-680.
45. Nakanishi H., Kimberly A.B., Exton J.H. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268:1993;13-16.
46. Hannun Y.A. Function of ceramide in coordinating cellular responses to stress. Science. 274:1996;1855-1859.