Energy depletion differently affects membrane transport and intracellular metabolism of riboflavin taken up by isolated rat enterocytes

Journal of Nutrition

Volumn 129, Issue 2, 1999, Pages 406-409

  Gastaldi, Giulia ^a   Laforenza, Umberto ^a   Casirola, Donatella ^b   Ferrari, Giuseppina ^a   Tosco, Marisa ^c   Rindi, Gianguido ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Energy depletion; Intestinal absorption; Isolated enterocytes; Rats; Riboflavin

Indexed keywords

RIBOFLAVIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; CELL VIABILITY; CONCENTRATION RESPONSE; ENERGY METABOLISM; INCUBATION TIME; INTESTINE ABSORPTION; INTESTINE CELL; INTRACELLULAR TRANSPORT; MICHAELIS CONSTANT; NONHUMAN; RAT; TIME; VITAMIN METABOLISM;

ANIMALIA;

EID: 0032915357     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/129.2.406     Document Type: Article

References (26)

1. Aw, T. Y., Jones, D. P. & McCormick, D. B. (1983) Uptake of riboflavin by isolated rat liver cells. J. Nutr. 113: 1249-1254.
2. Baur, H., Kasparek, S. & Pfaff, E. (1975) Criteria of viability of isolated liver cells. Hoppe-Seyler's Z. Physiol. Chem. 356 (suppl.): 827-838.
3. Bowers-Komro, D. M. & McCormick, D. B. (1987) Riboflavin uptake by isolated rat kidney cells. In: Flavins and Flavoproteins (McCormick, D. B. & Edmondson, D. E., eds.), pp. 449-453. DeGruyter, Berlin, Germany.
4. Bowers-Komro, D. M., Yasmada, Y. & McCormick, D. B. (1989) Substrate specificity and variables affecting efficiency of mammalian flavin adenine dinucleotide synthetase. Biochemistry 28: 8439-8445.
5. Casirola, D., Gastaldi, G., Ferrari, G., Kasai, S. & Rindi, G. (1993) Riboflavin uptake by rat small intestinal brush border membrane vesicles. A dual mechanism involving specific membrane binding. J. Membr. Biol. 135: 217-223.
6. Casirola, D., Kasai, S., Gastaldi, G., Ferrari, G. & Matsui, K. (1994) Specificity of riboflavin molecular groups for riboflavin binding to rat small intestinal brush border membrane. J. Nutr. Sci. Vitaminol. 40: 289-301.
7. Glantz, S. A. (1988) Statistica per Discipline Biomediche: Programma Applicativo. McGraw-Hill Libri Italia, Milano, Italy.
8. Hegazy, E. & Schwenk, M. (1983) Riboflavin uptake by isolated enterocytes of guinea pig. J. Nutr. 113: 1702-1707.
9. Joseph, T. & McCormick, D. B. (1995) Uptake and metabolism of riboflavin-5′-α-D-glucoside by rat and isolated liver cells. J. Nutr. 125: 2194-2198.
10. Kasai, S., Nakano, H., Kinoshita, T., Miyake, Y., Maeda, K. & Matsui, K. (1988) Intestinal absorption of riboflavin, studied by an in situ circulation system using radioactive analogues. J. Nutr. Sci. Vitaminol. 34: 265-280.
11. Kasai, S., Nakano, H., Maeda, K. & Matsui, K. (1990) Purification, properties and function of flavokinase from rat intestinal mucosa. J. Biochem. 107: 298-303.
12. + channel in isolated intestinal epithelial cells. Am. J. Physiol. 243: C116-C123.
13. Kumar, C. K., Yanagawa, N., Ortiz, A. & Said, H. M. (1998) Mechanism and regulation of riboflavin uptake by human renal proximal tubule epithelial cell line HK-2. Am. J. Physiol. 274: F104-F110.
14. Lambooy, J. P. (1975) Biological activities of analogues of riboflavin. In: Riboflavin (Rivlin., R. S., ed.), pp. 303-367. Plenum Press, New York, NY.
15. Lowry, O. H., Rosebrough, N. J., Farr, A. J. & Randall, R. J. (1951) Protein measurements with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.
16. McCormick, D. B. (1975) Metabolism of riboflavin. In: Riboflavin (Rivlin, R. S., ed.), pp. 153-198. Plenum Press, New York, NY.
17. 6, biotin and C. Proc. Soc. Exp. Biol. Med. 202: 265-270.
18. Middleton, H. M., III (1990) Uptake of riboflavin by rat intestinal mucosa in vitro. J. Nutr. 120: 588-593.
19. National Research Council (1985) Guide for the Care and Use of Laboratory Animals. Publication no. 85-23 (rev.), National Institutes of Health, Bethesda, MD.
20. Oka, M. & McCormick, D. B. (1987) Complete purification and general characterization of FAD synthetase from rat liver. J. Biol. Chem. 262: 7418-7422.
21. Randoin, L. & Causeret, J. (1947) Constitution d'un regime alimentaire equilibré pour les jeunes rats blancs destines au dosage des vitamines A et D par les methodes biologiques. Bull. Soc. Hyg. Aliment. 35: 14-18.
22. Ricci, V. & Rindi, G. (1992) Thiamin uptake by rat isolated enterocytes: relationship between transport and phosphorylation. Arch. Int. Physiol. Biochim. Biophys. 100: 275-279.
23. Rindi, G. & Laforenza, U. (1997) In vitro systems for studying thiamin transport in mammals. Methods Enzymol. 279: 118-131.
24. Said, H. M. & Ma, T. Y. (1994) Mechanism of riboflavin uptake by Caco-2 human intestinal epithelial cells. Am. J. Physiol. 266: G15-G21.
25. Snedecor, G. W. & Cochran, W. G. (1967) In: Statistical Methods, pp. 91-119 and 135-171. Iowa State University Press, Ames, IA.
26. Wilson, F. A. & Treanor, L. L. (1975) Characterization of the passive and active transport mechanisms for bile acid uptake into rat isolated intestinal epithelial cells. Biochim. Biophys. Acta 406: 280-293.