GH response to exercise: Assessment of the pituitary refractory period, and relationship with circulating components of the GH-IGF-I axis in adolescent females

Journal of Pediatric Endocrinology and Metabolism

Volumn 12, Issue 1, 1999, Pages 47-55

  Eliakim, Alon ^a,c   Brasel, Jo Anne ^a   Cooper, Dan M ^b  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MEIR MEDICAL CENTER   (Israel)

Author keywords

Adolescents; Exercise; Female; GH; IGF I; Refractory period

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

ADOLESCENT; AEROBIC CAPACITY; ANAEROBIC CAPACITY; ARTICLE; BICYCLE ERGOMETRY; CLINICAL PROTOCOL; EXERCISE; FEMALE; FITNESS; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; HUMAN; HUMAN EXPERIMENT; HYPOPHYSIS; NORMAL HUMAN; PROVOCATION TEST; PUBERTY; REFRACTORY PERIOD;

EID: 0032914119     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.1999.12.1.47     Document Type: Article

References (37)

1. Cappon J, Brasel JA, Mohan S, Cooper DM. Effect of brief exercise on circulating insulin-like growth factor-I. J Appl Physiol 1994; 76: 1418-1422.
2. Felsing NE, Brasel J, Cooper DM. Effect of low-and high-intensity exercise on circulating growth hormone in men. J Clin Endocrinol Metab 1992; 75: 157-162.
3. Weltman A, Weltman JY, Hartman ML, Abbott RD, Rogol AD, Evans WS, Veldhuis JD. Relationship between age, percentage body fat, fitness, and 24-hour growth hormone release in healthy young adults: effects of gender. J Clin Endocrinol Metab 1994; 78: 543-548.
4. Eliakim A, Brasel JA, Mohan S, Barstow TJ, Berman N, Cooper DM. Physical fitness, endurance training, and the GH-IGF-I system in adolescent females. J Clin Endocrinol Metab 1996; 81: 3986-3992.
5. Poehlman ET, Copeland KC. Influence of physical activity on insulin-like growth factor-I in healthy younger and older men. J Clin Endocrinol Metab 1990; 71: 1468-1473.
6. Kelley PJ, Eisman JA, Stuart MC, Pocock NA, Sambrook PN, Gwinn TH. Somatomedin-C, physical fitness, and bone density. J Clin Endocrinol Metab 1990; 70: 718-723.
7. Cowell CT. Short stature. In: Brook CGD, ed. Clinical Paediatric Endocrinology, 3rd Ed. Oxford: Blackwell Science, 1995; 136-172.
8. Rosenfeld RG, Albertsson-Wikland K, Cassorla F, Frasier SD, Hasegawa Y, Hintz RL. Diagnostic controversy: The diagnosis of childhood growth hormone deficiency revised. J Clin Endocrinol Metab 1995; 80: 1532-1540.
9. Cooper DM, Weiler-Ravell D, Whipp BJ, Wasserman K. Aerobic parameters of exercise as a function of body size during growth in children. J Appl Physiol 1984; 56: 628-634.
10. Eliakim A, Barstow TJ, Brasel JA, Ajie H, Lee WN, Renslo R, Berman N, Cooper DM. The effect of exercise training on energy expenditure, muscle volume, and peak oxygen uptake in adolescent females. J Pediatr 1996; 129: 537-543.
11. Wasserman K, Whipp BJ, Koyal SN, Beaver WL. Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol 1973; 35: 236-243.
12. 2 consequent to exercise and hypoxia. J Appl Physiol 1989; 66: 936-942.
13. Cappon JP, Ipp E, Brasel JA, Cooper DM. Acute effects of high-fat and high-glucose meals on the growth hormone response to exercise. J Clin Endocrinol Metab 1993; 76: 1418-1422.
14. Strasburger C, Barnard G, Toldo L, Zarmi B, Zadik Z, Kowarski A, Kohen F. Somatotropin as measured by a two-site time resolved immunofluorometric assay. Clin Chem 1989; 35: 913-917.
15. Carlsson LM, Rowland AM, Clark RG, Gesundheit N, Wong WL. Ligand-mediated immunofunctional assay for quantitation of growth hormone-binding protein in human blood. J Clin Endocrinol Metab 1991; 73: 1216-1223.
16. Daughaday WH, Kapadia M, Mariz I. Serum somatomedin binding proteins: physiologic significance and interference in radio ligand assay. J Lab Clin Med 1987; 109: 355-363.
17. Mohan S, Libanati C, Dony C, Lang K, Srinivasan N, Baylink DJ. Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids. J Clin Endocrinol Metab 1995; 80: 2638-2645.
18. Mohan S, Nakao Y, Honda Y, Landale E, Leser U, Dony C, Lang K, Baylink DJ. Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells. J Biol Chem 1995; 270: 20424-20431.
19. Beaver WL, Lamarra N, Wasserman K. Breath-by-breath measurement of true alveolar gas exchange. J Appl Physiol 1981; 51: 1662-1675.
20. Parkkola R, Kujala U, Rytokoski U. Response of the trunk muscles to training assessed by magnetic resonance imaging and muscle strength. Eur J Appl Physiol 1992; 65: 383-387.
21. Roman WJ, Fleckenstein J, Stray-Gundersen J, Alway SE, Peshock R, Gonyea WJ. Adaptations in the elbow flexors of elderly males after heavy-resistance training. J Appl Physiol 1993; 74: 750-754.
22. Veldhuis JD, Iranmanesh A, Ho KK, Waters MJ, Johnson ML, Lizarralde G. Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J Clin Endocrinol Metab 1991; 72: 51-59.
23. Hicks AL, MacDougall JD, Muckle TJ. Acute changes in high-density lipoprotein cholesterol with exercise of different intensities. J Appl Physiol 1987; 63: 1956-1960.
24. Casanueva FF, Villanueva L, Dieguez C, Diaz Y, Carbanez JA, Szoke B, Scanlon MF, Schally AV, Fernandez-Cruz A. Free fatty acids block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary. J Clin Endocrinol Metab 1987; 65: 634-642.
25. Casanueva FF, Villanueva L, Cabezas JA, Fernandez-Cruz A. Cholinergic mediation of growth hormone secretion elicited by arginine clonidine and physical exercise in man. J Clin Endocrinol Metab 1984; 59: 526-532.
26. Kelijman M, Frohman LA. The role of the cholinergic pathway in growth hormone feedback. J Clin Endocrinol Metab 1991; 72: 1081-1087.
27. Pontiroli AE, Lanzi R, Monti LD, Sandoli E, Pozza G. Growth hormone (GH) autofeedback on GH response to GH-releasing hormone. Role of free fatty acids and somatostatin. J Clin Endocrinol Metab 1991; 72: 492-495.
28. Wilkinson PW, Parkin JM. Growth hormone response to exercise in obese children. Lancet 1974; 2: 55.
29. Buckler JM. Exercise as a screening test for growth hormone release. Acta Endocrinol (Copenh) 1972; 69: 219-229.
30. Cooper DM, Barstow TJ, Bergner A, Lee W-NP. Blood glucose turnover during high-and low-intensity exercise. Am J Physiol 1989; 257: 405-412.
31. Coggan AR, Kohrt WM, Spina RJ, Kirwan JP, Bier DM, Holloszy JO. Plasma glucose kinetics during exercise in subjects with high and low lactate thresholds. J Appl Physiol 1992; 73: 1873-1880.
32. Bar-Or O. Pediatric Sports Medicine for the Practitioner. New York: Springer-Verlag, 1983; 182-191.
33. Reiter EO, Morris AH, MacGillivray MH, Weber D. Variable estimates of serum growth hormone concentrations by different radioassay systems. J Clin Endocrinol Metab 1988; 66: 68-71.
34. Andersson AM, Orskov H, Ranke MB, Shalet S, Skakkebaek NE. Interpretation of growth hormone provocative tests: Comparison of cutoff values in four European laboratories. Eur J Endocrinol 1995; 132: 340-343.
35. Rosenfeld RG, Lamson G, Pham H, Oh Y, Conover C, De Leon DD, Donovan SM, Ocrant I, Giudice L. Insulin-like growth factor binding proteins. Rec Prog Horm Res 1990; 46: 99-163.
36. Baxter RC, Martin JL. Radioimmunoassay of growth hormone dependent insulin-like growth factor binding protein in human plasma. J Clin Invest 1986; 78: 1504-1512.
37. Jargosky SE, Pham HM, Wilson KF, Liu F, Giudice LC, Rosenfeld RG. Measurements and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting. J Clin Endocrinol Metab 1992; 131: 3051-3060.