-
2
-
-
0022919663
-
Pharmacokinetics of mitoxantrone in man and laboratory animals
-
Batra VK, Morrison JA, Woodward DL, Siverd NS and Yacobi A (1986) Pharmacokinetics of mitoxantrone in man and laboratory animals. Drug Metab Rev 17:311-329.
-
(1986)
Drug Metab Rev
, vol.17
, pp. 311-329
-
-
Batra, V.K.1
Morrison, J.A.2
Woodward, D.L.3
Siverd, N.S.4
Yacobi, A.5
-
3
-
-
0029927340
-
Pharmacological and toxicological aspects of new imidazoacridinone antitumor agents
-
Berger B, Marquardt H and Westendorf J (1996) Pharmacological and toxicological aspects of new imidazoacridinone antitumor agents. Cancer Res 56:2094-2104.
-
(1996)
Cancer Res
, vol.56
, pp. 2094-2104
-
-
Berger, B.1
Marquardt, H.2
Westendorf, J.3
-
4
-
-
0025950675
-
Evidence for oxidative activation of mitoxantrone in human, pig and rat
-
Blanz J, Mewes K, Ehninger G, Proksch B, Waidelich D, Greger B and Zeller K-P (1991) Evidence for oxidative activation of mitoxantrone in human, pig and rat. Drug Metab Disp 19:871-880.
-
(1991)
Drug Metab Disp
, vol.19
, pp. 871-880
-
-
Blanz, J.1
Mewes, K.2
Ehninger, G.3
Proksch, B.4
Waidelich, D.5
Greger, B.6
Zeller, K.-P.7
-
5
-
-
0029828920
-
Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer
-
Burger AM, Double JA, Konopa J and Bibby MC (1996) Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer. Br J Cancer 74:1369-1374.
-
(1996)
Br J Cancer
, vol.74
, pp. 1369-1374
-
-
Burger, A.M.1
Double, J.A.2
Konopa, J.3
Bibby, M.C.4
-
6
-
-
0031706984
-
Pharmacokinetics and tissue distribution of the imidazoacridinone C1311 in tumour bearing mice
-
Calabrese CR, Bibby MC, Double JA and Loadman PM (1998) Pharmacokinetics and tissue distribution of the imidazoacridinone C1311 in tumour bearing mice. Cancer Chemother Pharmacol 42:379-385.
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, pp. 379-385
-
-
Calabrese, C.R.1
Bibby, M.C.2
Double, J.A.3
Loadman, P.M.4
-
7
-
-
0030964821
-
Analysis of the imidazoacridinone C1311 by high performance liquid chromatography
-
Calabrese CR and Loadman PM (1997) Analysis of the imidazoacridinone C1311 by high performance liquid chromatography. J Chromatogr 690:275-281.
-
(1997)
J Chromatogr
, vol.690
, pp. 275-281
-
-
Calabrese, C.R.1
Loadman, P.M.2
-
8
-
-
0022533438
-
Identification of human urinary mitoxantrone metabolites
-
Chiccarelli FS, Morrison JA, Cosulich DB, Perkinson NA and Ridge DN (1986) Identification of human urinary mitoxantrone metabolites. Cancer Res 46:4858-4861.
-
(1986)
Cancer Res
, vol.46
, pp. 4858-4861
-
-
Chiccarelli, F.S.1
Morrison, J.A.2
Cosulich, D.B.3
Perkinson, N.A.4
Ridge, D.N.5
-
9
-
-
0025165116
-
5-[(Aminoalkyl)amino] imidazo[4,5,1-de] acridin-6-ones as a novel class of antineoplastic agents. Synthesis and biological activity
-
Cholody WM, Martelli S, Paradziej-Lukowicz J and Konopa J (1990) 5-[(Aminoalkyl)amino] imidazo[4,5,1-de] acridin-6-ones as a novel class of antineoplastic agents. Synthesis and biological activity. J Med Chem 33:49-52.
-
(1990)
J Med Chem
, vol.33
, pp. 49-52
-
-
Cholody, W.M.1
Martelli, S.2
Paradziej-Lukowicz, J.3
Konopa, J.4
-
10
-
-
0015787295
-
Method for tissue culture evaluation of the cytotoxic activity of drugs active through the formation of metabolites
-
Dolfini E, Martini A, Donelli MG, Morasca L and Garattini S (1973) Method for tissue culture evaluation of the cytotoxic activity of drugs active through the formation of metabolites. Eur J Cancer 9:375-378.
-
(1973)
Eur J Cancer
, vol.9
, pp. 375-378
-
-
Dolfini, E.1
Martini, A.2
Donelli, M.G.3
Morasca, L.4
Garattini, S.5
-
11
-
-
0017870840
-
Chemotherapy of transplantable adenocarcinomas of the colon in mice
-
Double JA and Cifuentes de Castro L (1978) Chemotherapy of transplantable adenocarcinomas of the colon in mice. Cancer Treat Rep 62:85-90.
-
(1978)
Cancer Treat Rep
, vol.62
, pp. 85-90
-
-
Double, J.A.1
Cifuentes De Castro, L.2
-
12
-
-
0024426375
-
The MTT assay underestimates the growth inhibitory effects of interferons
-
Jabbar SAB, Twentyman PR and Watson JV (1989) The MTT assay underestimates the growth inhibitory effects of interferons. Br J Cancer 60:523-528.
-
(1989)
Br J Cancer
, vol.60
, pp. 523-528
-
-
Jabbar, S.A.B.1
Twentyman, P.R.2
Watson, J.V.3
-
13
-
-
0026737244
-
Glucuronidalion of drugs: A re-valuation of the pharmacological significance of the conjugates and modulating factors
-
Kroemer HK and Klotz U (1992) Glucuronidalion of drugs: A re-valuation of the pharmacological significance of the conjugates and modulating factors. Clin Pharmcokinet 23:292-310.
-
(1992)
Clin Pharmcokinet
, vol.23
, pp. 292-310
-
-
Kroemer, H.K.1
Klotz, U.2
-
15
-
-
0002778358
-
Pharmacokinetics and metabolism of mitoxantrone
-
Macpherson JS, Smyth JF, Clements JA, Ramsay MW, Warrington PS, Leonard RCF and Wolf CR (1984) Pharmacokinetics and metabolism of mitoxantrone. Br J Cancer 50:252-253.
-
(1984)
Br J Cancer
, vol.50
, pp. 252-253
-
-
Macpherson, J.S.1
Smyth, J.F.2
Clements, J.A.3
Ramsay, M.W.4
Warrington, P.S.5
Leonard, R.C.F.6
Wolf, C.R.7
-
16
-
-
0029983041
-
QSAR of acridines III. Structure-activity relationship for antitumor imidazoacridinones and intercorrelations between in vivo and in vitro tests
-
Mazerska Z, Augustin E, Dziegielewski J, Cholody WM and Konopa J (1996) QSAR of acridines III. Structure-activity relationship for antitumor imidazoacridinones and intercorrelations between in vivo and in vitro tests. Anticancer Drug Des 11:73-88.
-
(1996)
Anticancer Drug Des
, vol.11
, pp. 73-88
-
-
Mazerska, Z.1
Augustin, E.2
Dziegielewski, J.3
Cholody, W.M.4
Konopa, J.5
-
17
-
-
0026575978
-
In vitro activity of the novel inodloquinone EO9 and the influence of pH on cytotoxicity
-
Phillips RM, Hulbert PB, Bibby MC, Sleigh NR and Double JA (1992) In vitro activity of the novel inodloquinone EO9 and the influence of pH on cytotoxicity. Br J Cancer 65:359-364.
-
(1992)
Br J Cancer
, vol.65
, pp. 359-364
-
-
Phillips, R.M.1
Hulbert, P.B.2
Bibby, M.C.3
Sleigh, N.R.4
Double, J.A.5
-
18
-
-
0029920458
-
Inhibition of DNA topoisomerase II by imidazoacridinones, new antineoplastic agents with strong activity against solid tumors
-
Skladanowski A, Plisov SY, Konopa J and Larsen AK (1996) Inhibition of DNA topoisomerase II by imidazoacridinones, new antineoplastic agents with strong activity against solid tumors. Mol Pharmacol 49:772-780.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 772-780
-
-
Skladanowski, A.1
Plisov, S.Y.2
Konopa, J.3
Larsen, A.K.4
-
19
-
-
0003377396
-
Low level multidrug resistance expression to C1311, a potential clinical candidate
-
Warr JR, Quinn DM, Double JA and Bibby MC (1997) Low level multidrug resistance expression to C1311, a potential clinical candidate. Br J Cancer 75 (Suppl 1):33.
-
(1997)
Br J Cancer
, vol.75
, Issue.SUPPL. 1
, pp. 33
-
-
Warr, J.R.1
Quinn, D.M.2
Double, J.A.3
Bibby, M.C.4
-
20
-
-
16744368637
-
United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia
-
Workman P, Twentyman P, Balkwill F, Balmain A, Chaplin D, Double J, Embleton J, Newell D, Raymond R, Stables J, Stephens T and Wallace J (1998) United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia. Br J Cancer 77:1-10.
-
(1998)
Br J Cancer
, vol.77
, pp. 1-10
-
-
Workman, P.1
Twentyman, P.2
Balkwill, F.3
Balmain, A.4
Chaplin, D.5
Double, J.6
Embleton, J.7
Newell, D.8
Raymond, R.9
Stables, J.10
Stephens, T.11
Wallace, J.12
|