Efficient alternative synthetic route to diltiazem via (2R,3S)-3-(4- methoxyphenyl)glycidamide

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 2, 1999, Pages 146-150

  Yamada, Shin ichi ^a   Tsujioka, Ikuko ^a   Shibatani, Takeji ^a   Yoshioka, Ryuzo ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Addition reaction; Diltiazem; Glycidamide; Ring closing reaction

Indexed keywords

2 AMINOTHIOPHENOL; 2,3 DIHYDRO 3 HYDROXY 2 (4 METHOXYPHENYL) 1,5 BENZOTHIAZEPIN 4(5H) ONE; 3 (4 METHOXYPHENYL)GLYCIDAMIDE; AMIDE; AMMONIA; BENZENE DERIVATIVE; BENZOTHIAZEPINE DERIVATIVE; DILTIAZEM; METHYL 3 (4 METHOXYPHENYL)GLYCIDATE; THIOPHENOL DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; VASODILATOR AGENT;

AMIDATION; ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0032912844     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.146     Document Type: Article

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