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Volumn 27, Issue 3, 1999, Pages 342-350

Metabolism of the new liposomal anticancer drug N4-octadecyl-1-β-D arabinofuranosylcytosine in mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTARABINE DERIVATIVE; LIPOSOME; N4 OCTADECYL 1 BETA DEXTRO ARABINOFURANOSYCYTOSINE; UNCLASSIFIED DRUG;

EID: 0032911243     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (34)
  • 3
    • 0029969561 scopus 로고    scopus 로고
    • In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes. Identification of metabolites and effects of clofibrate or phenobarbital pretreatment
    • Boucher JL, Delaforge M, Salaun JP, Pinot F, Durst F, Pflieger P and Mioskowski C (1996) In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes. Identification of metabolites and effects of clofibrate or phenobarbital pretreatment. Drug Metab Dispos 24:462-468.
    • (1996) Drug Metab Dispos , vol.24 , pp. 462-468
    • Boucher, J.L.1    Delaforge, M.2    Salaun, J.P.3    Pinot, F.4    Durst, F.5    Pflieger, P.6    Mioskowski, C.7
  • 4
    • 0019774881 scopus 로고
    • Determination of cytarabine and uracil arabinoside in human plasma and cerebrospinal fluid by high-performance liquid chromatography
    • Breithaupt H and Schick J (1981) Determination of cytarabine and uracil arabinoside in human plasma and cerebrospinal fluid by high-performance liquid chromatography. J Chromatogr 225:99-106.
    • (1981) J Chromatogr , vol.225 , pp. 99-106
    • Breithaupt, H.1    Schick, J.2
  • 6
    • 0020995804 scopus 로고
    • Treatment of acute leukemia - Advances in chemotherapy, immunotherapy and bone marrow transplantation
    • Gahrton G (1983) Treatment of acute leukemia - advances in chemotherapy, immunotherapy and bone marrow transplantation. Adv Cancer Res 40:255-329.
    • (1983) Adv Cancer Res , vol.40 , pp. 255-329
    • Gahrton, G.1
  • 7
    • 0015692518 scopus 로고
    • Distribution of kinase and deaminase of 1-β-D-arabinofuranosylcytosine in tissues of man and mouse
    • Ho DH (1973) Distribution of kinase and deaminase of 1-β-D-arabinofuranosylcytosine in tissues of man and mouse. Cancer Res 33:2816-2820.
    • (1973) Cancer Res , vol.33 , pp. 2816-2820
    • Ho, D.H.1
  • 8
    • 0015147420 scopus 로고
    • Clinical pharmacology of 1-β-D-arabinofuranosylcytosine
    • Ho DH and Frei E (1971) Clinical pharmacology of 1-β-D-arabinofuranosylcytosine. Clin Pharmacol Ther 12:944-954.
    • (1971) Clin Pharmacol Ther , vol.12 , pp. 944-954
    • Ho, D.H.1    Frei, E.2
  • 9
    • 0017684521 scopus 로고
    • Pharmacology of 5′-esters of 1-β-D-arabinofuranosylcytosine
    • Ho DHW and Neil GL (1977) Pharmacology of 5′-esters of 1-β-D-arabinofuranosylcytosine. Cancer Res 37:1640-1643.
    • (1977) Cancer Res , vol.37 , pp. 1640-1643
    • Ho, D.H.W.1    Neil, G.L.2
  • 10
    • 0029016470 scopus 로고
    • 4-hexadecyl-1-β-D-arabinofuranosylcytosine, a lipophilic derivative of 1-β-D-arabinofuranosylcytosine
    • 4-hexadecyl-1-β-D-arabinofuranosylcytosine, a lipophilic derivative of 1-β-D-arabinofuranosylcytosine. Br J Cancer 71:957-962.
    • (1995) Br J Cancer , vol.71 , pp. 957-962
    • Horber, D.H.1    Schott, H.2    Schwendener, R.A.3
  • 11
    • 0028980009 scopus 로고
    • 4-hexadecyl-1-β-D-arabinofuranosylcytosine in the human leukemic cell lines K-562 and U-937
    • 4-hexadecyl-1-β-D-arabinofuranosylcytosine in the human leukemic cell lines K-562 and U-937. Cancer Chemother Pharmacol 36:483-492.
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 483-492
    • Horber, D.H.1    Schott, H.2    Schwendener, R.A.3
  • 13
    • 0016224655 scopus 로고
    • 4-substituted 2,2′-anhydronucleosides
    • 4-substituted 2,2′-anhydronucleosides. J Med Chem 17:1076-1078.
    • (1974) J Med Chem , vol.17 , pp. 1076-1078
    • Kanai, T.1    Ichino, M.2
  • 15
    • 0024797070 scopus 로고
    • Antitumor activity and pharmacology of 1-β-D-arabinofuranosylcyiosine-5′-stearylphosphate: An orally active derivative of 1-β-D-arabinofuranosylcytosine
    • Kodama K, Morozumi M, Saitoh K, Kuninaka A, Yoshino H and Saneyoshi M (1989) Antitumor activity and pharmacology of 1-β-D-arabinofuranosylcyiosine-5′-stearylphosphate: An orally active derivative of 1-β-D-arabinofuranosylcytosine. Jpn J Cancer Res 80:679-685.
    • (1989) Jpn J Cancer Res , vol.80 , pp. 679-685
    • Kodama, K.1    Morozumi, M.2    Saitoh, K.3    Kuninaka, A.4    Yoshino, H.5    Saneyoshi, M.6
  • 19
    • 0027417363 scopus 로고
    • Cellular pharmacodynamics of anticancer drugs
    • Plunkett W and Gandhi V (1993) Cellular pharmacodynamics of anticancer drugs. Semin Oncol 20:30-63.
    • (1993) Semin Oncol , vol.20 , pp. 30-63
    • Plunkett, W.1    Gandhi, V.2
  • 21
    • 0029257168 scopus 로고
    • On the estimation of alternative pathways of fatty acid oxidation in the liver in vivo
    • Rognstad R (1995) On the estimation of alternative pathways of fatty acid oxidation in the liver in vivo. Bull Math Biol 57:191-203.
    • (1995) Bull Math Biol , vol.57 , pp. 191-203
    • Rognstad, R.1
  • 22
    • 0020054279 scopus 로고
    • 4-acyl and 2,2′-anhydro-3′-O-acyl derivatives as potential prodrugs
    • 4-acyl and 2,2′-anhydro-3′-O-acyl derivatives as potential prodrugs. J Med Chem 25:171-178.
    • (1982) J Med Chem , vol.25 , pp. 171-178
    • Rosowsky, A.1    Kim, S.H.2    Ross, J.3    Wick, M.M.4
  • 24
    • 33748815265 scopus 로고
    • Synthese von 4-Alkylcytosinnucleosiden und deren cytostatische Wirkung im L1210 Leukämiemodell der Maus
    • Schott H, Häussler MP and Schwendener RA (1994) Synthese von 4-Alkylcytosinnucleosiden und deren cytostatische Wirkung im L1210 Leukämiemodell der Maus. Liebigs Ann Chem 1994:465-470.
    • (1994) Liebigs Ann Chem , vol.1994 , pp. 465-470
    • Schott, H.1    Häussler, M.P.2    Schwendener, R.A.3
  • 28
    • 0030479332 scopus 로고    scopus 로고
    • The role of membranes and intracellular binding proteins in cytoplasmic transport of hydrophobic molecules: Fatty acid-binding proteins
    • Storch J, Herr FM, Hsu KT, Kim HK, Liou HL and Smith ER (1996) The role of membranes and intracellular binding proteins in cytoplasmic transport of hydrophobic molecules: Fatty acid-binding proteins. Comp Biochem Physiol B 115:333-339.
    • (1996) Comp Biochem Physiol B , vol.115 , pp. 333-339
    • Storch, J.1    Herr, F.M.2    Hsu, K.T.3    Kim, H.K.4    Liou, H.L.5    Smith, E.R.6
  • 29
    • 0024846207 scopus 로고
    • Biotransformation of 5-(2-chloroethyl)-2′-deoxyuridine in male NMR1 mice
    • Szinai I and De Clercq E (1989) Biotransformation of 5-(2-chloroethyl)-2′-deoxyuridine in male NMR1 mice. Drug Metab Dispos 17:683-689.
    • (1989) Drug Metab Dispos , vol.17 , pp. 683-689
    • Szinai, I.1    De Clercq, E.2
  • 32
    • 0028180444 scopus 로고
    • Clinical pharmacology of 1-β-D-arabinofuranosylcytosine-5′-stearylphosphate, an orally administered long-acting derivative of low-dose 1-β-D-arabinofuranosylcytosine
    • Ueda T, Kamiya K, Urasaki Y, Wataya S, Kawai Y, Tsutani H, Sugiyama M and Nakamura T (1994) Clinical pharmacology of 1-β-D-arabinofuranosylcytosine-5′-stearylphosphate, an orally administered long-acting derivative of low-dose 1-β-D-arabinofuranosylcytosine. Cancer Res 54:109-113.
    • (1994) Cancer Res , vol.54 , pp. 109-113
    • Ueda, T.1    Kamiya, K.2    Urasaki, Y.3    Wataya, S.4    Kawai, Y.5    Tsutani, H.6    Sugiyama, M.7    Nakamura, T.8
  • 33
    • 0014238247 scopus 로고
    • 4-substituted derivatives of 1-β-D-arabinofuranosylcytosine and -5-fluorocytosine
    • 4-substituted derivatives of 1-β-D-arabinofuranosylcytosine and -5-fluorocytosine. J Med Chem 11:144-148.
    • (1968) J Med Chem , vol.11 , pp. 144-148
    • Wempen, I.1    Miller, N.2    Falco, E.A.3    Fox, J.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.