Localization of nitric oxide synthase isoforms in porcine ocular tissues

Current Eye Research

Volumn 18, Issue 5, 1999, Pages 375-380

  Meyer, Peter ^a   Champion, Claudine ^a   Schlötzer Schrehardt, Ursula ^b   Flammer, Josef ^a   Haefliger, Ivan O ^a  

^a UNIVERSITY EYE CLINIC   (Switzerland)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Aqueous humor; Immunohistochemistry; Nitric oxide; Nitric oxide synthase; Porcine eye

Indexed keywords

MONOCLONAL ANTIBODY; NITRIC OXIDE SYNTHASE;

ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CHOROID; CILIARY BODY; CILIARY BODY EPITHELIUM; CONJUNCTIVA; CONTROLLED STUDY; CORNEA; CYTOPLASM; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME LOCALIZATION; EYE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IRIS; MACROPHAGE; MICROSCOPY; NONHUMAN; OPTIC NERVE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA; SCLERA; SWINE; UVEA; VASCULAR ENDOTHELIUM;

ANIMALS; EYE; IMMUNOHISTOCHEMISTRY; MACROPHAGES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; SWINE; TISSUE DISTRIBUTION;

EID: 0032911222     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.18.5.375.5355     Document Type: Article

References (17)

1. Ignarro LJ. Nitric oxide. A novel signal transduction mechanism for transcellular communication. Hypertension 1990;16:477-83.
2. Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Ann. Rev. Biochem. 1994;63:175-95.
3. Kröncke KD, Fehsel K, Kolb-Bachofen V. Inducible nitric oxide synthase and its product nitric oxide, a small molecule with complex biological activities. Biol. Chem. Hoppe Seyler 1995;376:327-43.
4. Haefliger IO, Meyer P, Flammer J, Lüscher TF. The vascular endothelium as a regulator of the ocular circulation: a new concept in ophthalmology? Surv. Ophthalmol. 1994;39:123-32.
5. Nathanson JA, McKee M. Identification of an extensive system of nitric oxide-producing cells in the ciliary muscle and outflow pathway of the human eye. Invest. Ophthalmol. Vis. Sci. 1995;36:1765-73.
6. Perez MTR, Larsson B, Alm P, Andersson KE, Ehinger B. Localization of neuronal nitric oxide synthase-immunoreactivity in rat and rabbit retinas. Exp. Brain Res. 1995;104:20717.
7. Becquet F, Courtois Y, Goureau O. Nitric oxide in the eye: Multifaceted Roles and Diverse Outcomes. Surv. Ophthalmol. 1997;42:71-82.
8. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 1991;43:109-42.
9. Nathan C, Xei QW. Nitric oxide synthases: roles, tolls and controls. Cell. 1994;78:915-18.
10. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB. 1992;6:3051-64.
11. Haufschild T, Nava E, Meyer P, Flammer J, Lüscher TF, Haefliger IO. Spontaneous calcium-independent nitric oxide synthase activity in porcine ciliary processes. Biochem. Biophys. Res. Comm. 1996;222:786-9.
12. Liu R, Flammer J, Lüscher TF, Haefliger IO. β-adrenergic agonist-induced nitrite production in isolated pig ciliary processes. Graefe's Arch. Clin. Exp. Ophthalmol. 1998; 236:613-6.
13. Yamamoto R, Bredt DS, Snyder SH, Stone RA. The localization of nitric oxide synthase in the eye and related cranial ganglia. Neuroscience 1993;54:189-200.
14. Osborne N, Barnett NL, Herrera AJ. NADPH diaphorase localization and nitric oxide synthetase activity in the retina and anterior uvea of the rabbit eye. Brain Res. 1993;610:194-8.
15. Lütjen-Drecoll E, Rohen JW. Anatomy of aqueous humor formation and drainage. In: Textbook of Ophthalmology. Kaufmann PL and Mittag TW (eds). Vol. 7: Glaucoma. 1994:1.1.-1.16
16. Kishimoto J, Tsuchiya T, Emson PC, Nakayama Y. Immobilization-induced stress activates neuronal nitric oxide synthase (nNOS) mRNA and protein in hypothalamic-pituitary-adrenal axis in rats. Brain Res. 1996;720:159-171.
17. Koch K, Lambrecht H, Haberecht M, Redburn D, Schmidt HH. Functional coupling of a calcium/calmodulin-dependent nitric oxide synthase and a soluble guanylyl cyclase in vertebrate photoreceptor cells. EMBO J. 1994;13:3312-20.