Ampullary carcinoma: Prognostic significance of ploidy, cell-cycle analysis and proliferating cell nuclear antigen (PCNA)

Hepato-Gastroenterology

Volumn 46, Issue 26, 1999, Pages 1187-1191

  Crucitti, A ^a   Masetti, R ^a   Breccia, C ^a   Coppola, R ^a   Magistrelli, P ^a   Nuzzo, G ^a   Maggiano, N ^a   Picciocchi, A ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Ampullary carcinoma; Ploidy; Prognosis; Proliferative cell nuclear antigen; S phase fraction

Indexed keywords

CYCLINE; DNA; MONOCLONAL ANTIBODY;

ADULT; AGED; ANEUPLOIDY; ANTIGEN EXPRESSION; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CELL CYCLE; CELL PROLIFERATION; CLINICAL ARTICLE; DEVICE; DIPLOIDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MUCINOUS CARCINOMA; PLOIDY; PRIORITY JOURNAL; PROGNOSIS; TUMOR VOLUME; VATER PAPILLA CARCINOMA;

ADULT; AGED; AMPULLA OF VATER; CELL CYCLE; COMMON BILE DUCT NEOPLASMS; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PLOIDIES; PROGNOSIS; PROLIFERATING CELL NUCLEAR ANTIGEN; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 0032910123     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. 1 Baisch H, et al: DNA ploidy and cell-cycle analysis in pancreatic and ampullary carcinoma: flow cytometric study of formalin-fixed paraffin-embedded tissue. Virchows Archiv A Pathol Anat 1990; 417:145-150.
2. 2 Isozaki I, et al: The significance of proliferating cell nuclear antigen (PCNA) expression in cancer of the ampulla of Vater in terms of prognosis. Surgery Today (Jpn J Surg) 1994; 24:494-499.
3. 3 Shyr Y, et al: DNA ploidy as a major prognostic factor in resectable ampulla of Vater cancers. J Surg Oncol 1993; 53:220-225.
4. 4 Soon Lee C: Differences in cell proliferation and prognostic significance of proliferating cell nuclear antigen and Ki-67 antigen immunoreactivity in situ and invasive carcinoma of the extrahepatic biliary tract. Cancer 1996; 78(9):1881-1887.
5. 5 Hedley DW, et al: Application of DNA flow-cytometry to paraffin-embedded archival material for the study and its clinical significance. Cytometry 1985; 6:327-333.
6. 6 Robbins BA, et al: Immunohistochemical detection of proliferative cell nuclear antigen in solid human malignancies. Arch Pathol Lab Med 1987; 11:841-845.
7. 7 Jaurreta JR, Bernat R, Verdaguer J, et al: DNA ploidy and S+G2M fraction (proliferative index) as prognostic determinants in human periampullary cancer. Hepato-Gastroenterol 1995; 42:740-747.
8. 8 Jorba R, Fernandez-Cruz L: Prognostic implication of DNA ploidy and cell-cycle analysis in pancreatic and periampullary carcinoma. Hepato-Gastroenterol 1994; 41:507-508.
9. 9 Weger AR, Falkner UG, Schwab G, et al: Nuclear DNA distribution pattern of the parenchymal cells in adenocarcinomas of the pancreas and chronic pancreatitis. Gastroenterol 1990; 99:237-242.
10. 10 Nakao A, et al: Prognosis of cancer of the duodenal papilla of Vater in relation to clinicopathological tumor extension. Hepato-Gastroenterol 1994; 41:73-78.
11. 11 Chan C, Herrera MF, De La Garza L, et al: Clinical behavior and prognostic factors of periampullary adenocarcinoma. Ann Surg 1995; 222(5):632-637.