Functional comparison of muscarinic partial agonists at muscarinic receptor subtypes hM1, hM2, hM3, hM4 and hM5 using microphysiometry

British Journal of Pharmacology

Volumn 126, Issue 7, 1999, Pages 1620-1624

  Wood, Martyn D ^a   Murkitt, Karen L ^a   Ho, Michael ^a   Watson, Jeannette M ^a   Brown, Frank ^a   Hunter, A Jacqueline ^a   Middlemiss, Derek N ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Microphysiometry; Muscarinic receptor; Partial agonists; Selectivity

Indexed keywords

CARBACHOL; MILAMELINE; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; PARTIAL AGONIST; RADIOLIGAND; RECEPTOR RESERVE; RECEPTOR SUBTYPE; SABCOMELINE; XANOMELINE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; FEMALE; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

EID: 0032909713     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702463     Document Type: Article

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