Activation of three classes of nonreceptor tyrosine kinases following Fcγ receptor crosslinking in human monocytes

Clinical Immunology

Volumn 90, Issue 1, 1999, Pages 55-64

  Pan, Xiao Qing ^a   Darby, Christine ^a   Indik, Zena K ^a   Schreiber, Alan D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CELL SURFACE PROTEIN; FOCAL ADHESION KINASE; PAXILLIN; PROTEIN TYROSINE KINASE; RECEPTOR PROTEIN;

ARTICLE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MONOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0032907347     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.1998.4644     Document Type: Article

References (61)

1. Ruiz P., Gomez F., Schreiber A. D. Impaired function of macrophage Fcγ receptors in end-stage renal disease. N. Engl. J. Med. 322:1990;717-722.
2. Gomez F., Ruiz P., Schreiber A. D. Impaired function of macrophage Fcγ receptors and bacterial infection in alcoholic cirrhosis. N. Engl. J. Med. 331:1994;1122-1129.
3. Isakov N., Wange B. A., Samelson L. E. The role of tyrosine kinases and phosphotyrosine-containing recognition motifs in regulation of the T cell-antigen receptor-mediated signal transduction pathway. J. Leukocyte Biol. 55:1994;265-271.
4. Brozna J. P., Hauff N. F., Phillips W. A., Johnston R. B. Activation of the respiratory burst in macrophages: Phosphorylation specifically associated with Fc receptor-mediated stimulation. J. Immunol. 141:1988;1642-1647.
5. Greenberg S., Chang P., Silverstein S. Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages. J. Exp. Med. 177:1993;529-534.
6. Klausner R. D., Samelson L. E. T cell antigen receptor activation pathways: The tyrosine kinase connection. Cell. 64:1991;875-878.
7. Connelly P. A., Farrell C. A., Merenda J. M., Conklyn M. J., Showell H. J. Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3). Biochem Biophys. Res. Commun. 177:1991;192-201.
8. Einspahr K. J., Abraham R. T., Binstadt B. A., Uehara Y., Leibson P. J. Tyrosine phosphorylation provides an early and requisite signal for the activation of natural killer cell cytotoxic function. Proc. Natl. Acad. Sci. USA. 88:1991;6279-6283.
9. Benhamou M., Gutkind J. S., Robbins K. C., Siraganian R. P. Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release. Proc. Natl. Acad. Sci. USA. 87:1990;5327-5330.
10. Ghazizadeh S., Fleit H. B. Tyrosine phosphorylation provides an obligatory early signal for FcγRII-mediated endocytosis in the monocytic cell line THP-1. J. Immunol. 152:1994;30-41.
11. McKenzie S. E., Schreiber A. D. Fcγ receptors in phagocytes. Curr. Opin. Hematol. 5:1998;16-21.
12. Indik Z. K., Hunter S., Huang M-M., Pan X-Q., Chien P., Kelly C., Levinson A. I., Kimberly R. P., Schreiber A. D. The high affinity Fcγ receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: The γ subunit of FcγRIIIA imparts phagocytic function to FcγRI. Exp. Hematol. 22:1994;599-600.
13. Indik Z. K., Kelly C., Chien P., Levinson A. I., Schreiber A. D. Human FcγRII, in the absence of other Fcγ receptors, mediates a phagocytic signal. J. Clin. Invest. 88:1991;1766-1771.
14. Mitchell M. A., Huang M-M., Chien P., Indik Z. K., Pan X-Q., Schreiber A. D. Substitutions and deletions in the cytoplasmic domain of the phagocytic Fc receptor FcγRIIA: Effect on receptor tyrosine phosphorylation and phagocytosis. Blood. 84:1994;1753-1759.
15. Park J-G., Isaacs R. E., Chien P., Schreiber A. D. In the absence of other Fc receptors, FcγRIIIA transmits a phagocytic signal that requires the cytoplasmic domain of its γ subunit. J. Clin. Invest. 92:1993;1967-1973.
16. Park J. G., Murray R. K., Chien P., Darby C., Schreiber A. D. Conserved cytoplasmic tyrosine residues of the γ subunit are required for a phagocytic signal mediated by FcγRIIIA. J. Clin. Invest. 92:1993;2073-2079.
17. Indik Z. K., Pan X-Q., Huang M-M., McKenzie S. E., Levinson A. I., Schreiber A. D. Insertion of cytoplasmic tyrosine sequences into the non-phagocytic receptor FcγRIIB establishes phagocytic function. Blood. 83:1994;2072-2080.
18. Indik Z. K., Park J-G., Pan X-Q., Schreiber A. D. Induction of phagocytosis by a protein tyrosine kinase. Blood. 85:1995;1175-1180.
19. Huang M-M., Indik Z. K., Brass L. F., Hoxie J. A., Schreiber A. D., Brugge J. S. Activation of FcγRII induces tyrosine phosphorylation of multiple proteins including FcγRII. J. Biol. Chem. 267:1992;5467-5473.
20. Cambier J. C. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL). Immunol. Today. 16:1995;110.
21. Reth M. Antigen receptor tail clue. Nature. 338:1989;383-384.
22. Ernst L. K., Duchemin A-M., Anderson C. L. Association of the high affinity receptor of IgG (FcγRI) with the γ subunit of the IgE receptor. Proc. Natl. Acad. Sci. USA. 90:1993;6023-6027.
23. Masuda M., Roos D. Association of all three types of FcγR (CD64, CD32 and CD16) with a γ-chain homodimer in cultured human monocytes. J. Immunol. 151:1993;7188-7195.
24. Scholl P. R., Geha R. S. Physical association between the high affinity receptor for IgG (FcγRI) and the γ subunit of the high affinity IgE receptor (FcεRI). Proc. Natl. Acad. Sci. USA. 90:1993;8847-8850.
25. Scholl P. R., Ahern D., Geha R. S. Protein tyrosine phosphorylation induced via the IgG receptors FcγRI and FcγRII in the human monocytic cell line THP-1. J. Immunol. 149:1992;1751-1757.
26. Kiener P. A., Rankin B. M., Burkhardt A. L., Schieven G. L., Gilliland L. K., Rowley R., Bolen J. B., Ledbetter J. A. Cross-linking of Fcγ receptor I (FcγRI) and receptor II (FcγRII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72syk protein tyrosine kinase. J. Biol. Chem. 268:1993;2442-2448.
27. Agarwal A., Salem P., Robbins K. C. Involvement of p72syk, a protein tyrosine kinase in Fcγ receptor signaling. J. Biol. Chem. 268:1993;15900-15905.
28. Darby C., Geahlen R. L., Schreiber A. D. Stimulation of macrophage FcγRIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95Vav and p62/GAP-associated protein. J. Immunol. 52:1994;5429-5437.
29. Greenberg S., Chang P., Silverstein S. C. Tyrosine phosphorylation of the γ subunit of Fcγ receptor, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages. J. Biol. Chem. 269:1994;3897-3902.
30. Hutchcroft J. E., Harrison M. L., Geahlen R. L. B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase. J. Biol. Chem. 266:1991;14846-14849.
31. Taniguchi T., Kobayashi T., Kondo J., Takahashi K., Nakamura H., Suzuki J., Nagai K., Yamada T., Nakamura S., Yamamura H. Molecular cloning of a porcine gene syk that encodes a 72-kDa protein tyrosine kinase showing high susceptibility to proteolysis. J. Biol. Chem. 266:1991;15790-15796.
32. Hanada F., Aoki M., Akiyama T., Toyoshima K. Association of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophils. Proc. Natl. Acad. Sci. USA. 90:1993;6304-6309.
33. Inoue K., Yamamoto T., Toyoshima K. Specific expression of human cFgr in natural immunity effector cells. Mol. Cell. Biol. 10:1990;1789-1792.
34. Ley T. J., Connolly N. L., Katamine S., Cheah M. S. C., Senior R. M., Robbins K. C. Tissue specific expression and developmental regulation of human Fgr proto-oncogene. Mol. Cell. Biol. 9:1989;92-99.
35. FAK. Proc. Natl. Acad. Sci. USA. 89:1992;5192-5196.
36. Schaller M. D., Parsons J. T. Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol. 6:1994;705-710.
37. Hanks S. K., Calalb M. B., Harper M. C., Patel S. K. Focal adhesion protein kinase phosphorylated in response to cell spreading on fibronectin. Proc. Natl. Acad. Sci. USA. 89:1992;8487-8489.
38. FAK. J. Cell Sci. 105:1993;637-645.
39. FAK. J. Cell Biol. 119:1992;893-903.
40. Bustelo X. R., Ledbetter J. A., Barbacid M. Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates. Nature. 356:1992;68-71.
41. Margolis B., Hu P., Katsav S., Li W., Oliver J. M., Ullrich A., Weiss A., Schlessinger J. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domains and transcription factor motifs. Nature. 356:1992;71-74.
42. Turner C. E., Glenney J. R., Burridge K. Paxillin: A new vinculin-binding protein. J. Cell Biol. 111:1990;1059-1066.
43. Glenney J. R., Zokas L. Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton. J. Cell Biol. 108:1989;2401-2408.
44. Weng Z., Taylor J. A., Turner C. E., Brugge J. S., Seidel-Dugan C. Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells. J. Biol. Chem. 268:1993;14956-14963.
45. Kolanus W., Romeo C., Seed B. Lineage-independent activation of immune system effector function by myeloid Fc receptors. EMBO J. 11:1992;4861-4868.
46. Odin J. A., Edberg J. C., Painter C. J., Kimberly R. P., Unkeless J. C. Regulation of phagocytosis and [Ca2+] flux by distinct regions of an Fc receptor. Science. 254:1991;1785-1788.
47. Silverstein S. C., Greenberg S., DiVergilio F., Steinberg T. H. Phagocytosis. Fundamental Immunology. 1989;New York. p. 703-720.
48. FAK. J. Cell Biol. 119:1992;905-912.
49. Kornberg L., Earp H. S., Parsons J. T., Schaller M. D., Juliano R. L. Cell adhesion or integrin clustering increases phosphorylation of a focal-adhesion associated tyrosine kinase. J. Biol. Chem. 267:1992;23439-23442.
50. Batt D. B., Roberts T. M. Cell density modulates protein-tyrosine phosphorylation. J. Biol. Chem. 273:1998;3408-3414.
51. Zachary I. Focal adhesion kinase. Int. J. Biochem. Cell Biol. 29:1997;929-934.
52. Indik Z. K., Park J. G., Hunter S., Schreiber A. D. The molecular dissection of Fcγ receptor mediated phagocytosis. Blood. 86:1995;4389-4399.
53. Zhou M., Lublin D. M., Link D. C., Brown E. J. Distinct tyrosine kinase activation and Triton-X 100 insolubility upon FcγRII or FcγRIIIB ligation in polymorphonuclear leukocytes. Implications for immune complex activation of the respiratory burst. J. Biol. Chem. 270:1995;13553-13560.
54. Yan S. R., Fumagalli L., Dusi S., Berton G. Tumor necrosis factor triggers redistribution to a Triton-X-100 insoluble cytoskeletal fraction of beta 2 integrins, NAPH oxidase components, tyrosine phosphorylated proteins, and the protein tyrosine kinase p58fgr in human neutrophils adherent to fibrinogen. J. Leukocyte Biol. 58:1995;595-606.
55. C-FGRLYN. FEBS Lett. 380:1996;198-203.
56. Faris M., Gaskin F., Parsons J. T., Fu S. M. CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kDa tyrosine phosphorylated protein. J. Exp. Med. 179:1994;1923-1931.
57. Crowley M. T., Costello P. S., Fitzer-Attas C. J., Turner M., Meng F., Lowell C., Tybulewicz V. L. J., DeFranco A. L. A critical role for Syk in signal transduction and phagocytosis mediated by Fcγ receptors on macrophages. J. Exp. Med. 186:1997;1027-1039.
58. Ghazizadeh S., Bolen J. B., Fleit H. B. Physical and functional association of Src-related protein tyrosine kinases with FcγRII in monocytic THP-1 cells. J. Biol. Chem. 269:1994;8878-8884.
59. Wang A. V. T., Scholl P. R., Geha R. F. Physical and functional association of the high affinity immunoglobulin G receptor (FcγRI) with the kinases Hck and Lyn. J. Exp. Med. 180:1994;1165-1170.
60. FAK. Mol. Cell. Biol. 15:1995;2635-2645.
61. BCR/ABL. J. Biol. Chem. 270:1995;5039-5047.