2,4-(Hydroxyphenyl)-ethanol, an antioxidative agent produced by Candida spp., impairs neutrophilic yeast killing in vitro

FEMS Microbiology Letters

Volumn 170, Issue 2, 1999, Pages 319-325

  Cremer, Josef ^a,b   Vatou, Vassilia ^a   Braveny, Ilja ^a  

^a Inst Med Microbiol Immunol Hyg   (Germany)

^b Medical Diagnostic Institute Kempten   (Germany)

Author keywords

2,4 (Hydroxyphenyl) ethanol; Candida; Chemiluminescence; Neutrophil; Pathogenicity; Respiratory burst reaction

Indexed keywords

ALCOHOL DERIVATIVE; ANTIOXIDANT;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CELL KILLING; CHEMOLUMINESCENCE; CONTROLLED STUDY; FLOW CYTOMETRY; GEL CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUTROPHIL; PATHOGENICITY; PHAGOCYTOSIS; PRIORITY JOURNAL; RESPIRATORY BURST; YEAST CELL;

CANDIDA; CHEMILUMINESCENT MEASUREMENTS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLOW CYTOMETRY; FUNGAL PROTEINS; HUMANS; NEUTROPHILS; OXIDOREDUCTASES; PHAGOCYTOSIS; PHENYLETHYL ALCOHOL; RESPIRATORY BURST; ZYMOSAN;

CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS;

EID: 0032907155     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(98)00560-6     Document Type: Article

References (13)

1. Dismukes, W.E. (1998) Established and emerging invasive mycoses. Infect. Dis. Clin. Pract. 7 (Suppl. 1), S49-S56.
2. Lehrer, R.I. (1975) The fungicidal mechanisms of human monocytes: I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms. J. Clin. Invest. 55, 338-346.
3. Lehrer, R.I. (1971) Measurement of candidacidal activity of specific leukocyte types in mixed cell populations: II. Normal and chronic granulomatous disease eosinophils. Infect. Immun. 3, 800-802.
4. Hilger, A.E. and Danley, D.L. (1980) Alteration of polymorphonuclear leukocyte activity by viable C. albicans. Infect. Immun. 27, 714-720.
5. Sasada, M. and Johnston, Jr., R.B. (1980) Macrophage microbicidal activity - Correlation between phagocytosis-associated oxidative metabolism and the killing of Candida by macrophages. J. Exp. Med. 152, 85-98.
6. Marodi, L., Forehand, J.R. and Johnston, Jr., R.B. (1991) Mechanisms of host defence against Candida species - II. Biochemical basis for the killing of Candida by mononuclear phagocytes. J. Immunol. 146, 2790-2794.
7. Ferrante, A. and Thong, Y.H. (1980) Optimal conditions for simultaneous purification of mononuclear and polymorphonuclear leucocytes from human blood by the Hypaque-Ficoll method. J. Immunol. Methods 36, 109-117.
8. Remold, H., Fasold, H. and Staib, F. (1968) Purification and characterization of a proteolytic enzyme from C. albicans. Biochim. Biophys. Acta 167, 399-406.
9. Martin, E. and Bhakdi, S. (1991) Quantitative analysis of opsonophagocytosis and of killing of C. albicans by human peripheral blood leucocytes by using flow cytometry. J. Clin. Microbiol. 29, 2013-2023.
10. Weyst, E.S., Todd, W.R., Mason, H.S. and Van Bruggen, J.T. (1966) Textbook of Biochemistry. Macmillan, New York.
11. Nenashev, V.A., Pridachina, N.N., El'-Registran, G.I., Zolotareva, I.N. and Batrakov, S.G. (1994) Effect of autoinducers of anabiosis for some microorganisms on rat liver mitochondria respiration. Biokhimiia 59, 11-15.
12. Borg-von Zepelin, M. and Schuff-Werner, P. (1992) Chemiluminescence of polymorphonuclear granulocytes in the presence of selected Candida species. Mycoses 35, 121-129.
13. Schuit, K.E. (1979) Phagocytosis and intracellular killing of pathogenic yeasts by human monocytes and neutrophils. Infect. Immun. 24, 932-938.