Effects of oxygen on invertase expression in continuous culture of recombinant Saccharomyces cerevisiae containing the SUC2 gene

Applied Microbiology and Biotechnology

Volumn 51, Issue 3, 1999, Pages 334-339

  Pyun, Y R ^a   Jo, J S ^a   Park, J W ^a   Shin, H H ^a  

^a Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA FRUCTOFURANOSIDASE; GENE PRODUCT; GLUCOSE; OXYGEN;

ARTICLE; CELL CULTURE; CELL GROWTH; MOLECULAR CLONING; NONHUMAN; PLASMID; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; YEAST CELL;

ANAEROBIOSIS; BETA-FRUCTOFURANOSIDASE; CULTURE MEDIA; FUNGAL PROTEINS; GENE EXPRESSION; GLUCOSE; GLYCOSIDE HYDROLASES; OXYGEN; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TIME FACTORS;

SACCHAROMYCES CEREVISIAE;

EID: 0032906181     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530051399     Document Type: Article

References (17)

1. Andreasen AA, Stier TJB (1953) Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium. J Cell Comp Physiol 41: 23-26
2. Andreasen AA, Stier TJB (1954) Anaerobic nutrition of Saccharomyces cerevisiae. II. Unsaturated fatty acid requirement for growth in a defined medium. J Cell Comp Physiol 43: 271-281
3. Bailey JE, Ollis DF (1986) Biochemical engineering kinetics, McGrawHill, NY
4. Carlson M, Bostein D (1982) Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase. Cell 28: 145-154
5. Dodyk F, Rothestein A (1980) Factors influencing the appearance of invertase in Saccharomyces cerevisiae. Arch Biochem Biophys 104: 478-486
6. Fiechter A, Seghezzi W (1992) Regulation of glucose metabolism in growing yeast cells. J. Biotechnol 27: 27-45
7. Fiechter A, Fuhrmann, GF, Kappeli O (1981) Regulation of glucose metabolism in growing yeast cell. Adv Microbiol Physiol 22: 123-183
8. Jang JK, Pyun YR, Shin PK, Seo JH (1990) Analysis of cloned SUC2 gene expression in continuous culture of recombinant Saccharomyces cerevisiae. Biotechnol Bioeng 36: 960-964
9. Macy JM, Miller MW (1983) Anaerobic growth of Saccharomyces cerevisiae in the absence of oleic acid ergosterol. Ach Microbiol 134: 64-67
10. Patkar AY, Seo JH, Lim HC (1993) Modeling and optimization of cloned invertase expression in Saccharomyces cerevisiae. Biotechnol Bioeng 41: 1066-1074
11. Petrick M, Käppeli O, Fickter A (1983) An expanded concept for the glucose effect in the yeast Saccharomyces uvarum. Involvement of short and long term regulation. J Gen Microbiol 129: 43-49
12. Sarokin L, Carlson M (1984) Upstream region required for regulated expression of the glucose-repressible SUC2 gene of Saccharomyces cerevisiae. Mol Cell Biol 4: 2750-2757
13. Toda K (1976) Invertase biosynthesis by Saccharomyces calsbergensis in batch and continuous cultures. Biotechnol Bioeng 18: 1103-1115
14. Toda K, Yabe I, Yamagata T (1980) Kinetics of biphasic growth of yeast in continuous and fed-batch cultures. Biotechnol Bioeng 22: 1805-1827
15. Verduyn C, Postma E, Scheffers WA, Dijken JP van (1990) Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J Gen Micobiol 136: 395-403
16. Vitolo M, Vairo MLR, Borzani W (1987) Invertase activity of intact cells of Saccharomyces cerevisiae growing on sugarcane molasses. II. Unsteady-state continuous-culture tests. Biotech Bioeng 30: 9-14
17. Zurbriggen B, Kühne AB, Kallio P, Käppeli O, Fiechter A (1989) Controlled expression of heterologous cytochrome P450e cDNA in Saccharomyces cerevisiae. II. Development of cultivation process for heterologous cytochrome P450e production. J Biotechnol 9: 273-286