Quality and quantity of the humoral immune response in healthy elderly and young subjects after annually repeated influenza vaccination

Journal of Infectious Diseases

Volumn 179, Issue 1, 1999, Pages 31-36

  De Bruijn, I A ^a   Remarque, E J ^a   Jol Van Der Zijde, C M ^a   Van Tol, M J D ^a   Westendorp, R G J ^a   Knook, D L ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTINATION INHIBITING ANTIBODY; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INFLUENZA VACCINE;

ADULT; AGED; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMORAL IMMUNITY; INFLUENZA; INFLUENZA VACCINATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIBODIES, VIRAL; ANTIBODY AFFINITY; HEMAGGLUTINATION INHIBITION TESTS; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFLUENZA A VIRUS; INFLUENZA VACCINES; TIME FACTORS;

EID: 0032905778     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314540     Document Type: Article

References (31)

1. Beyer WEP, de Bruijn IA, Palache AM, Westendorp RGJ, Osterhaus ADME. Protection against influenza after annually repeated vaccination. A meta-analysis of serological and field studies. Arch Intern Med (in press).
2. Govaert TME, Sprenger MJW, Dinant GJ, Aretz K, Masurel N, Knottnerus JA. Immune response to influenza vaccination in elderly people. A randomized double blind placebo controlled trial. Vaccine 1994;12:1185-9.
3. Powers DC, Murphy BR, Fries LF, Adler WH, Clements ML. Reduced infectivity of cold-adapted influenza A H1N1 viruses in the elderly: correlation with serum and local antibodies. J Am Geriatr Soc 1992;40:163-7.
4. Remarque EJ, de Bruijn IA, Boersma WJA, Masurel N, Ligthart GJ. Altered antibody response to influenza (H1N1) vaccine in healthy elderly people as determined by HI, ELISA, and neutralisation assay. J Med Virol 1998;55:82-7.
5. de Bruijn IA, Remarque EJ, Beyer WEP, LeCessie S, Masurel N, Ligthart GJ. Annually repeated influenza vaccination improves humoral responses to several influenza virus strains in healthy elderly. Vaccine 1997;15:1323-9.
6. Ligthart GJ, Corberand JX, Hernandez-Pando R, et al. Admission criteria for immunogerontological studies in man: the SENIEUR protocol. Mech Ageing Dev 1984;28:47-55.
7. Beyer WEP, Palache AM, Baljet M, Masurel N. Antibody induction by influenza vaccines in the elderly: a review of the literature. Vaccine 1989;7:385-94.
8. Masurel N, Bartelds AJM, Baars AMJ, van Wijngaarden JK, Claas ECJ. Influenza in het seizoen 1992/'93; vaccinsamenstelling voor het seizoen 1993/'94 [in Dutch]. Ned Tijdschr Geneeskd 1993;137:1987-90.
9. Masurel N. Relation between Hong Kong virus and former human A2 isolates and the A/Equi2 virus in human sera collected before 1957. Lancet 1969;1:907-10.
10. Remarque EJ, van Beek WCA, Ligthart GJ, et al. Improvement of the immunoglobulin subclass response to influenza vaccine in elderly nursing-home residents by the use of high-dose vaccines. Vaccine 1993;11:649-54.
11. Renfrey S, Watts A. Morphological and biochemical characterization of influenza vaccines commercially available in the United Kingdom. Vaccine 1994;12:747-52.
12. Pullen GR, Fitzgerald MG, Hosking CS. Antibody avidity determination by ELISA using thiocyanate elution. J Immunol Methods 1986;86:83-7.
13. Hoskins TW, Davies JR, Allchin A, Miller CL, Pollock TM. Controlled trial of inactivated influenza vaccine containing the A/Hong Kong strain during an outbreak of influenza due to the A/England/42/72 strain. Lancet 1973;ii:116-20.
14. Hoskins TW, Davies JR, Smith AJ, Allchin A, Miller CL, Pollock TM. Influenza at Christ's Hospital: March 1974. Lancet 1976;i:105-8.
15. Hoskins TW, Davies JR, Smith AJ, Miller CL, Allchin A. Assessment of inactivated influenza-A vaccine after three outbreaks or influenza-A at Christs's Hospital. Lancet 1979;i:33-5.
16. Keitel WA, Cate TR, Couch RB. Efficacy of sequential annual vaccination with inactivated influenza virus vaccine. Am J Epidemiol 1988;127:353-64.
17. Gross PA, Quinnan GV, Weksler ME, Setia U, Douglas RG. Relation of chronic disease and immune response to influenza vaccine in the elderly. Vaccine 1989;7:303-8.
18. Howells CHL, Vesselinova-Jenkins CK, Evans AD, James J. Influenza vaccination and mortality from bronchopneumonia in the elderly. Lancet 1975;i:381-3.
19. Glathe H, Bigl S, Grosche A. Comparison of humoral immune responses to trivalent influenza split vaccine in young, middle aged, and elderly people. Vaccine 1993;11:702-5.
20. Hobson D, Baker FA, Curry RL. Effect of influenza vaccines in stimulating antibody in volunteers with prior immunity. Lancet 1973;2:155-6.
21. Keitel WA, Cate TR, Couch RB, Huggins LL, Hess KR. Efficacy of repeated annual immunization with inactivated influenza virus vaccines over a five year period. Vaccine 1997;15:1114-22.
22. Pyhälä R, Kumpulainen V, Alanko S, Forsten T. HI antibody kinetics in adult volunteers immunized repeatedly with inactivated trivalent influenza vaccine in 1990-1992. Vaccine 1994;12:947-52.
23. McElhaney JE, Meneilly GS, Lechelt KE, Beattie BL, Bleackley RC. Antibody response to whole-virus and split-virus influenza vaccines in successful ageing. Vaccine 1993;11:1055-60.
24. Powers DC, Belshe RB. Effect of age on cytotoxic T lymphocyte memory as well as serum and local antibody responses elicited by inactivated influenza virus vaccine. J Infect Dis 1993;167:584-92.
25. Palache AM, Beyer WEP, Sprenger MJW, et al. Antibody response after influenza immunization with various vaccine doses: A double-blind, placebo-controlled, multi-centre, dose-response study in elderly nursing-home residents and young volunteers. Vaccine 1993;11:3-9.
26. Hennessy AV, Davenport FM. Epidemiologic implications of the distribution by age of antibody response to experimental influenza virus vaccines. J Immunol 1958;80:114-21.
27. Pyhälä R, Kinnunen L, Kumpulainen V, Ikonen N, Kleemola M, Cantell K. Vaccination-induced HI antibody to influenza A (HINI) viruses in poorly primed adults under circumstances of low antigenic drift. Vaccine 1993;11:1013-7.
28. Potter CW, Oxford JS. Determinants of immunity to influenza in man. Br Med Bull 1979;35:69-75.
29. Iorio AM, Rivosecchi P, Zei T, Merletti L. Immune response to trivalent inactivated influenza vaccine in young and elderly subjects. Vaccine 1989;7:341-4.
30. Kishimoto S, Takahama T, Mizumachi H. In vitro immune response to the 2,4,6-TNP determinant in aged C57BL/6J mice: changes in the humoral immune response, avidity for the TNP determinant, and responsivenessto LPS effect with aging. J Immunol 1976;116:294-300.
31. Schoub BD, Blackburn NK, Johnson S, McAnerney JM, Miller B. Low antibody avidity in elderly chickenpox patients. J Med Virol 1992;37:113-5.