Salbutamol pretreatment does not change eosinophil percentage and eosinophilic cationic protein concentration in hypertonic saline-induced sputum in asthmatic subjects

Clinical and Experimental Allergy

Volumn 29, Issue 5, 1999, Pages 712-718

  Cianchetti, S ^a   Bacci, E ^b   Ruocco, L ^b   Bartoli, M L ^b   Carnevali, S ^b   Dente, F L ^b   Di Franco, A ^b   Giannini, D ^b   Scuotri, L ^b   Vagaggini, B ^b   Paggiaro, P L ^b  

^a CISANELLO HOSPITAL   (Italy)

^b NONE

Author keywords

ECP; Eosinophils; Histamine; Salbutamol; Sputum induction

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; EOSINOPHIL CATIONIC PROTEIN; HISTAMINE; SALBUTAMOL; SODIUM CHLORIDE;

ADULT; ALLERGIC ASTHMA; ARTICLE; BRONCHODILATATION; BRONCHOSPASM; BRONCHUS REACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; EOSINOPHIL; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; INHALATIONAL DRUG ADMINISTRATION; LEUKOCYTE DIFFERENTIAL COUNT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SPUTUM ANALYSIS; TREATMENT OUTCOME;

ADRENERGIC BETA-AGONISTS; ADULT; ALBUTEROL; ASTHMA; BLOOD PROTEINS; BRONCHIAL PROVOCATION TESTS; BRONCHODILATOR AGENTS; EOSINOPHILS; HISTAMINE; HUMANS; METHACHOLINE CHLORIDE; SALINE SOLUTION, HYPERTONIC; SINGLE-BLIND METHOD; SPECIMEN HANDLING; SPUTUM;

EID: 0032905636     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1999.00519.x     Document Type: Article

References (31)

1. 1 Pin I, Gibson GG, Kolendowicz R et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47:25-9.
2. 2 Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993; 147: 1126-31.
3. 3 Popov TA, Gottschalk R, Kolendowicz R, Dolovich J, Powers P, Hargreave FE. The evaluation of a cell dispersion method of sputum examination. Clin Exp Allergy 1994; 24:778-83.
4. 4 Bacci E, Cianchetti S, Paggiaro PL et al. Comparison between hypertonic saline and isotonic saline-induced sputum in the evaluation of airway inflammation in subjects with moderate asthma. Clin Exp Allergy 1996; 26:1395-400.
5. 5 Popov TA, Pizzichini MMM, Pizzichini R et al. Some technical factors influencing the induction of sputum for cell analysis. Eur Respir J 1995; 8:559-65.
6. 6 Smith CM, Anderson SD. Inhalation challenge using hypertonic saline in asthmatic subjects: a comparison with responses to hyperpnoea, methacholine and water. Eur Respir J 1990; 3:144-51.
7. 7 Johnson M. SS2-agonists as anti-inflammatory therapies in the lung. Agents Actions 1993; 41 (Suppl.): 27-45.
8. 8 Global Initiative for Asthma. Global strategy for asthma management and prevention. NHLBI/WHO Workshop Report, March 1993. NIH/NHLBI Publication Number 95-3659, January 1995.
9. 9 Bacci E, Cianchetti S, Bartoli ML et al. Reproducibility of induced sputum cell analysis in the evaluation of airway inflammation in asthma. Eur Respir J 1996; 9 (Suppl):119s.
10. 10 Paggiaro PL, Bacci E, Paoletti P et al. Bronchoalveolar lavage and morphology of the airways after cessation of exposure in asthmatic subjects sensitized to toluene diisocyanate. Chest 1990; 98:536-42.
11. 11 Siegel S, Castellan NJ Jr. Nonparametric statics for the behavioral sciences, 2nd edn. New York: McGraw-Hill, 1992.
12. 12 Glantz SA. Primer of biostatistics, 2nd edn. New York: McGraw-Hill, 1988.
13. 13 Kramer MS, Feinstein AR. Clinical biostatistics. LIV. The biostatistics of concordance. Clin Pharmacol Ther 1981; 29:111-23.
14. 14 Umeno E, McDonald DM, Nadel JA. Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation. J Clin Invest 1990; 85:905-8.
15. 15 Boschetto P, Roberts NM, Rogers DF, Barnes PJ. The effect of antiasthma drugs on microvascular leak in guinea pig airways. Am Rev Respir Dis 1989; 139:416-21.
16. 16 Whelan CJ, Johnson M. Inhibition by salmeterol of increased vascular permeability and granulocyte accumulation in guinea-pig lung and skin. Br J Pharmacol 1992; 105:831-8.
17. 17 Holtz O, Jorres RA, Speckin P et al. Ozone exposure of human subjects increases percentages of neutrophils and lymphocytes in induced sputum. Am J Respir Crit Care Med 1997; 155:A732.
18. 18 Gershman NH, Liu H, Liu J, Wong HH, Fahy JV. Fractional analysis of sequential sputum samples during sputum induction. Am J Respir Crit Care Med 1997; 155:A819.
19. 19 Church MK, Hiroi J. Inhibition of IgE-dependent histamine release from human dispersed lung mastcells by anti-allergic drugs and salbutamol. Br J Pharmacol 1987; 90:421-9.
20. 20 Howarth PH, Durham SR, Lee TM, Kay AB, Church MK, Holgate ST. Influence of albuterol, cromolyn sodium and ipratropium broide on the airway and circulating mediator responses to allergen bronchial provocation in asthma. Am Rev Respir Dis 1985; 132:986-92.
21. 21 Munoz NM, Vita AJ, Neely SP et al. Beta adrenergic modulation of formyl-methionine-leucine-phenylalamine stimulates secretion of eosinophil peroxidase and leukotriene C4. J Pharmacol Exp Ter 1994; 268:1339-43.
22. 22 Feldman RD. Beta-adrenergic receptor-mediated suppression of interleukin-2 receptors in human lymphocytes. J Immunol 1987; 139:3355-9.
23. 23 Gravelyn TR, Pan PM, Eschenbacher WL. Mediator release in an isolated airway segment in subjects with asthma. Am Rev Respir Dis 1988; 137:641-6.
24. 24 Silber G, Proud D, Warner J et al. In vivo release of inflammatory mediators by hyperosmolar solutions. Am Rev Respir Dis 1988; 137:606-12.
25. 25 Fahy JV, Liu J, Wong H, Boushey HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993; 147:1126-31.
26. 26 Fahy JV, Liu J, Wong H, Boushey HA. Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: a method for studyng allergic airway inflammation. J Allergy Clin Immunol 1994; 93:1031-9.
27. 27 Chong LK, Cooper E, Vardey CJ, Peachell PJ. Salmeterol inhibition of mediator release from human lung mast cells by bete-adrenoreceptor-dependent and independent mechanisms. Br J Pharmacol 1998; 123:1009-15.
28. 28 Pedersen B, Dahl R, Larsen BB, Venge P. The effect of salmeterol on the early-and late-phase reaction by bronchial allergen and postchallenge variation in bronchial reactivity, blood cosinophils, serum eosinophil cationic protein, and serum eosinophil protein X. Allergy 1993; 48:377-82.
29. 29 Schoeffel RE, Anderson SD, Altouynan EC. Bronchial hyperreativity in response to inhalation of ultrasonically nebulized solutions of distilled water and saline. BMJ 1981; 63:459-71.
30. 30 Wong HH, Fahy JV. Safety of one method of sputum induction in asthmatic subjects. Am J Respir Crit Care Med 1997; 156:299-303.
31. 31 Smith CM, Anderson SD. Inhalation provocation tests using nonisotonic aerosols. J Allergy Clin Immunol 1989; 84:781-90.