Admission standard electrocardiogram for early risk stratification in patients with unstable coronary artery disease not eligible for acute revascularization therapy: A TRIM substudy

American Heart Journal

Volumn 137, Issue 1, 1999, Pages 24-33

  Holmvang, Lene ^a   Clemmensen, Peter ^a   Wagner, Galen ^b   Grande, Peer ^a  

^a University of Copenhagen   (Denmark)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CORONARY ARTERY DISEASE; CORONARY RISK; ELECTROCARDIOGRAM; FEMALE; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; ST SEGMENT DEPRESSION; STATISTICAL ANALYSIS;

EID: 0032905596     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-8703(99)70456-4     Document Type: Article

References (26)

1. Blanke H, Cohen M, Schlueter GU, Karsch KR, Rentrop KP. Electrocardiographic and coronary arteriographic correlations during acute myocardial infarction. Am J Cardiol 1984;54:249-55.
2. Rude RE, Poole WK, Muller JE, Turi Z, Rutherford J, Parker C, et al. Electrocardiographic and clinical criteria for recognition of acute myocardial infarction based on analysis of 3,697 patients. Am J Cardiol 1983;52:936-42.
3. Falk E. Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion. Circulation 1985;71:699-708.
4. Effects of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction. Results of the TIMI IIIB Trial. Thrombolysis in Myocardial Ischemia. Circulation 1994;89:1545-56.
5. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FIT) Collaborative Group. Lancet 1994;343:311-22.
6. Olson HG, Lyons KP, Aronow WS, Stinson PJ, Kuperus J, Waters HJ. The high-risk angina patient. Identification by clinical features, hospital course, electrocardiography and technetium-99m stannous pyrophosphate scintigraphy. Circulation 1981;64:674-84.
7. Ohman EM, Armstrong PW, Christenson RH, Granger CB, Katus HA, Hamm CW, et al. Cardiac troponin T levels for risk stratification in acute myocardial ischemia. GUSTO IIA Investigators. N Engl J Med 1996;335:1333-41.
8. Langer A, Freeman MR, Armstrong PW. ST segment shift in unstable angina: pathophysiology and association with coronary anatomy and hospital outcome. J Am Coll Cardiol 1989;13:1495-502.
9. Ayres SM. The electrocardiogram in the acute coronary syndromes. J Am Coll Cardiol 1990;16:1026-8.
10. Nyman I, Areskog M, Areskog NH, Swahn E, Wallentin L. Very early risk stratification by electrocardiogram at rest in men with suspected unstable coronary heart disease. The RISC Study Group. J Intern Med 1993;234:293-301.
11. Cannon CP, McCabe CH, Stone PH, Rogers WJ, Schactman M, Thompson BW, et al. The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q wave myocardial infarction: results of the TIMI III Registry ECG Ancillary Study. Thrombolysis in Myocardial Ischemia. J Am Coll Cardiol 1997;30:133-40.
12. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet 1988;2:349-60.
13. The TRIM study group. A low molecular weight, specific thrombin inhibitor, Inogatran, versus heparin, in unstable coronary artery disease in 1209 patients: a double blind, randomized dose finding study. Eur Heart J 1997;18:1416-25.
14. Low molecular-weight heparin during instability in coronary artery disease, Fragmin during Instability in Coronary Artery Disease (FRISC) study group. Lancet 1996;347:561-8.
15. Giri S, Waters DD. Pathophysiology and initial management of the acute coronary syndromes. Curr Opin Cardiol 1996;11:351-60.
16. Ogawa H, Hiramori K, Haze K, Saito M, Sumiyoshi T, Fukami K, et al. Classification of non-Q-wave myocardial infarction according to electrocardiographic changes. Br Heart J 1985;54:473-8.
17. Holmvang L, Hasbak P, Clemmensen P, Wagner GS, Grande P. Differences between local investigator and core-laboratory interpretation of the admission electrocardiogram in patients with unstable angina or non-Q myocardial infarction (A ThRombin Inhibition in Myocardial ischemia [TRIM] substudy). Am J Cardiol 1998;82:54-60.
18. Jain A, O'Rourke RA, Kleiger RE, Boden WE. ST-segment elevation on the initial ECG identifies low risk patients with a non-Q-wave MI [abstract]. Circulation 1997;96;1-272.
19. Willems JL, Willems RJ, Willems GM, Arnold AE, Van de Werf F, Verstraete M. Significance of initial ST segment elevation and depression for the management of thrombolytic therapy in acute myocardial infarction. European Cooperative Study Group for Recombinant Tissue-Type Plasminogen Activator. Circulation 1990;82:1147-58.
20. Mauri F, Gasparini M, Barbonaglia L, Santoro E, Grazia Franzosi M, Tognoni G, et al. Prognostic significance of the extent of myocardial injury in acute myocardial infarction treated by streptokinase (the GISSI trial). Am J Cardiol 1989;63:1291-5.
21. Sclarovsky S, Rechavia E, Strasberg B, Sagie A, Bassevich R, Kusniec J, et al. Unstable angina: ST segment depression with positive versus negative T wave deflections - clinical course, ECG evolution, and angiographic correlation. Am Heart J 1988;116:933-41.
22. Larsson H, Areskog M, Areskog NH, Jonasson T, Ringqvist I, Fellenius C, et al. The diagnostic and prognostic importance of ambulatory ST recording compared to a predischarge exercise test after an episode of unstable angina or non-Q wave myocardial infarction. Eur Heart J 1995;16:888-93.
23. Simoons ML, de Boer MJ, van den Brand MJ, van Miltenburg AJ, Hoorntje JC, Heyndrickx GR, et al. Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina. European Cooperative Study Group. Circulation 1994;89:596-603.
24. Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease. The RISC Group. Lancet 1990;336:827-30.
25. Theroux P, Waters D, Qiu S, McCans J, de Guise P, Juneau M. Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina. Circulation 1993;88:2045-8.
26. White HD, French JK, Norris RM, Williams BF, Hart HH, Cross DB. Effects of streptokinase in patients presenting within 6 hours of prolonged chest pain with ST segment depression. Br Heart J 1995; 73:500-5.