Cellular uptake of fluvastatin, an inhibitor of HMG-CoA reductase, by rat cultured hepatocytes and human aortic endothelial cells

British Journal of Clinical Pharmacology

Volumn 47, Issue 4, 1999, Pages 383-389

  Ohtawa, Masakatsu ^a   Masuda, Naoki ^a   Akasaka, Izumi ^a   Nakashima, Akinori ^a   Ochiai, Keiko ^a   Moriyasu, Matsuko ^b  

^a NOVARTIS PHARMA K K   (Japan)

^b Panapharm Laboratories Co Ltd   (Japan)

Author keywords

Cellular uptake; Fluvastatin; HMG CoA reductase inhibitor; Human aortic endothelial cells; Multispecific anion transporter; Rat primary cultured hepatocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; BILE ACID; BUFFER; CARBON 14; CHOLIC ACID; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRAVASTATIN; SODIUM ION; TAUROCHOLIC ACID;

ANIMAL CELL; ANION TRANSPORT; AORTA; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIFFUSION; DRUG UPTAKE; ENDOTHELIUM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INCUBATION TIME; LIQUID SCINTILLATION COUNTING; LIVER CELL CULTURE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TEMPERATURE; VASCULAR ENDOTHELIUM;

EID: 0032904757     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1999.00901.x     Document Type: Article

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