Functional expression of an inactivating potassium channel (Kv4.3) in a mammalian cell line

Cardiovascular Research

Volumn 41, Issue 1, 1999, Pages 212-219

  Franqueza, L ^a,b   Valenzuela, C ^b   Eck, J ^a   Tamkun, M M ^a,d   Tamargo, J ^b   Snyders, D J ^b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Antiarrhythmic agents; Arrhythmia; Ion channels; K channels; Membrane currents

Indexed keywords

BUPIVACAINE; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL LINE; COMPARATIVE STUDY; HEART ARRHYTHMIA; HUMAN; HUMAN CELL; MAMMAL CELL; MEMBRANE CHANNEL; MEMBRANE ELECTROPHYSIOLOGY; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; STEREOCHEMISTRY;

ANIMALS; BUPIVACAINE; CELL LINE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; ION TRANSPORT; MAMMALS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SHAL POTASSIUM CHANNELS;

EID: 0032904411     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00220-X     Document Type: Article

References (36)

1. + current in mammalian heart. In: Morad M, Kurachi Y, Noma A, Hosada M, editors, Molecular physiology and pharmacology of cardiac ion channels and transporters. Amsterdam: Kluwer, 1996:141-168.
2. Tseng-Crank JC, Tseng GN, Schwartz A, Tanouye MA. Molecular cloning and functional expression of a potassium channel cDNA isolated from a rat cardiac library. FEBS Lett 1990;268:63-68.
3. Po S, Roberds S, Snyders DJ, Tamkun MM, Bennett PB. Heteromultimeric assembly of human potassium channels. Molecular basis of a transient outward current?. Circ Res 1993;72:1326-1336.
4. + channels operating at subthreshold potentials with unique expression in heart and brain. J Neurophysiol 1996;75:2174-2179.
5. to-like potassium channel from ferret ventricle. Am J Physiol 1994;267:H1383-H1395.
6. + channel in ventricular muscle. A molecular correlate for the transient outward current. Circ Res 1996;79:659-668.
7. Deal K, England S, Tamkun M. Molecular physiology of cardiac potassium channels. Physiol Rev 1996;76:49-67.
8. Yeola SW, Snyders DJ. Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current. Cardiovasc Res 1997;33:540-547.
9. + current in rat ventricle. J Physiol (Lond) 1997;500:51-64.
10. + channel isoforms in rat ventricle. J Physiol (Lond) 1997;500:65-73.
11. + channels?. Circ Res 1995;77:361-369.
12. Roberds SL, Tamkun MM. Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart. Proc Natl Acad Sci USA 1991;88:1798-1802.
13. Dixon JE, McKinnon D. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ Res 1994;75:252-260.
14. Clark RB, Bouchard RA, Salinas-Stefanon E, Sanchez-Chapula J, Giles WR. Heterogeneity of action potential waveforms and potassium currents in rat ventricle. Cardiovasc Res 1993;27:1795-1799.
15. Wettwer E, Amos GJ, Posival H, Ravens U. Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin. Circ Res 1994;75:473-482.
16. Tseng GN, Hoffman BF. Two components of transient outward current in canine ventricular myocytes. Circ Res 1989;64:633-647.
17. Näbauer M, Beuckelmann DJ, Erdmann E. Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure. Circ Res 1993;73:386-394.
18. Serodio P, Kentros C, Rudy B. Identification of molecular components of A-type channels activating at subthreshold potentials. J Neurophysiol 1994;72:1516-1529.
19. + channel currents by quinidine. Circ Res 1993;73:351-359.
20. Snyders DJ, Knoth KM, Roberds SL, Tamkun MM. Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel. Mol Pharmacol 1992;41:322-330.
21. + current but not the inward rectifier in rat ventricular myocytes. J Pharmacol Exp Ther 1990;255:1038-1046.
22. + channel (Kv4.3). Meth Find Exp Clin Pharmacol (Abstract) 1997;19:141.
23. Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC. Green fluorescent protein as a marker for gene expression. Science 1994;263:802-805.
24. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 1981;391:85-100.
25. + channels. Ionic and gating current studies. J Gen Physiol 1985;85:539-554.
26. Snyders DJ, Tamkun MM, Bennett PB. A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression. J Gen Physiol 1993;101:513-543.
27. Josephson IR, Sanchez-Chapula J, Brown AM. Early outward current in rat single ventricular cells. Circ Res 1984;54:157-162.
28. Wettwer E, Amos G, Gath J, et al. Transient outward current in human and rat ventricular myocytes. Cardiovasc Res 1993;27:1662-1669.
29. + channel inactivation mediated by the concerted action of the cytoplasmic- and C-terminal domains. Biophys J 1997;72:163-174.
30. Hoshi T, Zagotta WN, Aldrich RW. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 1990;250:533-538.
31. Franqueza L, Longobardo M, Vicente J, et al. Molecular determinants of stereoselective bupivacaine block of hKv1.5 channels. Circ Res 1997;81:1053-1064.
32. Escande D, Coulombe A, Faivre J, Deroubaix E, Coraboeuf E. Two types of transient outward currents in adult human atrial cells. Am J Physiol 1987;252:H142-H148.
33. Fermini B, Wang Z, Duan D, Nattel S. Difference in rate dependence of transient outward current in rabbit and human atrium. Am J Physiol 1992;263:H1747-H1754.
34. + currents in isolated adult rat ventricular myocytes. J Gen Physiol 1991;97:973-1011.
35. Imaizumi Y, Giles WR. Quinidine-induced inhibition of transient outward current in cardiac muscle. Am J Physiol 1987;253:H704-H708.
36. Sanchez-Chapula J, Elizalde A, Navarro-Polanco R, Barajas H. Differences in outward currents between neonatal and adult rabbit ventricular cells. Am J Physiol 1994;266:H1184-H1194.