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Volumn 5, Issue 2, 1999, Pages 104-108

Expression of relaxin-like factor is down-regulated in human testicular Leydig cell neoplasia

Author keywords

Adenoma; Human testis; Hyperplasia; Leydig cell; Relaxin like factor

Indexed keywords

INSULIN; MESSENGER RNA; RELAXIN; RELAXIN LIKE FACTOR; SOMATOMEDIN; UNCLASSIFIED DRUG;

EID: 0032903364     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/5.2.104     Document Type: Article
Times cited : (45)

References (32)
  • 1
    • 0027365039 scopus 로고
    • Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells
    • Adham, I.M., Burkhardt, E., Benahmed, M. et al. (1993) Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells. J. Biol. Chem., 268, 26668-26672.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26668-26672
    • Adham, I.M.1    Burkhardt, E.2    Benahmed, M.3
  • 2
    • 0001911902 scopus 로고    scopus 로고
    • Leydig insulin-like hormone-deficient mice show male premeiotic arrest and germ cell death
    • Adham, I.M., Zimmermann, S. and Engel, W. (1997) Leydig insulin-like hormone-deficient mice show male premeiotic arrest and germ cell death. Reprod. Dom. Anim., 32, 73.
    • (1997) Reprod. Dom. Anim. , vol.32 , pp. 73
    • Adham, I.M.1    Zimmermann, S.2    Engel, W.3
  • 3
    • 0029908314 scopus 로고    scopus 로고
    • Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: Sequence and messenger ribonucleic acid analysis
    • Bathgate, R., Balvers, M., Hunt, N. et al. (1996) Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: sequence and messenger ribonucleic acid analysis. Biol. Reprod., 55, 1452-1457.
    • (1996) Biol. Reprod. , vol.55 , pp. 1452-1457
    • Bathgate, R.1    Balvers, M.2    Hunt, N.3
  • 4
    • 0029022502 scopus 로고
    • A novel Leydig cell cDNA-derived protein is a relaxin-like factor
    • Büllesbach, E. and Schwabe, C. (1995) A novel Leydig cell cDNA-derived protein is a relaxin-like factor. J. Biol. Chem., 270, 16011-16015.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16011-16015
    • Büllesbach, E.1    Schwabe, C.2
  • 5
    • 0028204907 scopus 로고
    • Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3)
    • Burkhardt, E., Adham, I.M., Brosig, B. et al. (1994) Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3). Genomics, 20, 13-19.
    • (1994) Genomics , vol.20 , pp. 13-19
    • Burkhardt, E.1    Adham, I.M.2    Brosig, B.3
  • 6
    • 0023039434 scopus 로고
    • Leydig cell tumor and metachronous Leydig cell hyperplasia: A case associated with gynecomastia and elevated urinary estrogens
    • Castle, W.N. and Richardson, J.R. (1986) Leydig cell tumor and metachronous Leydig cell hyperplasia: a case associated with gynecomastia and elevated urinary estrogens. J. Urol., 136, 1307-1308.
    • (1986) J. Urol. , vol.136 , pp. 1307-1308
    • Castle, W.N.1    Richardson, J.R.2
  • 7
    • 0029095815 scopus 로고
    • Cloning of a member of the insulin gene superfamily (INSL4) expressed in human placenta
    • Chassin, D., Laurent, A., Janneau, J.-L. et al. (1995) Cloning of a member of the insulin gene superfamily (INSL4) expressed in human placenta. Genomics, 29, 465-470.
    • (1995) Genomics , vol.29 , pp. 465-470
    • Chassin, D.1    Laurent, A.2    Janneau, J.-L.3
  • 8
    • 0030999939 scopus 로고    scopus 로고
    • Leydig cell hyperplasia and adenoma formation: Mechanisms and relevance to humans
    • Clegg, E.D., Cook, J.C., Chapin, R.E. et al. (1997) Leydig cell hyperplasia and adenoma formation: mechanisms and relevance to humans. Reprod. Toxicol., 11, 107-121.
    • (1997) Reprod. Toxicol. , vol.11 , pp. 107-121
    • Clegg, E.D.1    Cook, J.C.2    Chapin, R.E.3
  • 9
    • 0025189783 scopus 로고
    • Combination of the peroxidase antiperoxidase (PAP)- and avidin-biotin-peroxidase complex (ABC) techniques: An amplification alternative in immunocytochemical staining
    • Davidoff, M.S. and Schulze, W. (1990) Combination of the peroxidase antiperoxidase (PAP)- and avidin-biotin-peroxidase complex (ABC) techniques: an amplification alternative in immunocytochemical staining. Histochemistry, 93, 531-536.
    • (1990) Histochemistry , vol.93 , pp. 531-536
    • Davidoff, M.S.1    Schulze, W.2
  • 10
    • 0024555892 scopus 로고
    • Immunohistological determination of oestrogen receptor, progesterone receptor, and intermediate filaments in Leydig cell tumours, Leydig cell hyperplasia, and normal Leydig cells of the human testis
    • Düe, W., Dieckmann, K.-P., Loy, V. et al. (1989) Immunohistological determination of oestrogen receptor, progesterone receptor, and intermediate filaments in Leydig cell tumours, Leydig cell hyperplasia, and normal Leydig cells of the human testis. J. Pathol., 157, 225-234.
    • (1989) J. Pathol. , vol.157 , pp. 225-234
    • Düe, W.1    Dieckmann, K.-P.2    Loy, V.3
  • 11
    • 0028884041 scopus 로고
    • Expression of SQ10 (a preprorelaxin-like gene) in the pregnant rabbit placenta and uterus
    • Fields, P., Kondo, S., Tashima, L. et al. (1995) Expression of SQ10 (a preprorelaxin-like gene) in the pregnant rabbit placenta and uterus. Biol. Reprod., 53, 1139-1145.
    • (1995) Biol. Reprod. , vol.53 , pp. 1139-1145
    • Fields, P.1    Kondo, S.2    Tashima, L.3
  • 12
    • 13044273238 scopus 로고
    • Development of the testis and associated dislity
    • Gondos, B. and Riddick, D.H. (eds), Thieme, Stuttgart
    • Gondos, B. (1987) Development of the testis and associated dislity. In Gondos, B. and Riddick, D.H. (eds), Pathology of Infertility. Clinical Correlation in the Male and Female. Thieme, Stuttgart, pp. 219-241.
    • (1987) Pathology of Infertility. Clinical Correlation in the Male and Female , pp. 219-241
    • Gondos, B.1
  • 13
    • 0021240774 scopus 로고
    • Leydig cell hyperplasia in cryptorchid patients: Quantitative evoluation of Leydig cells in undescended and contralateral scrotal testes
    • Gotoh, M., Miyake, K. and Mitsuya, H. (1984) Leydig cell hyperplasia in cryptorchid patients: Quantitative evoluation of Leydig cells in undescended and contralateral scrotal testes. Urol. Res., 12, 159-164.
    • (1984) Urol. Res. , vol.12 , pp. 159-164
    • Gotoh, M.1    Miyake, K.2    Mitsuya, H.3
  • 15
    • 0003261715 scopus 로고
    • Histological evaluation of testicular biopsies
    • Schirren, C. and Holstein, A.F. (eds), Grosse Verlag, Berlin
    • Holstein, A.F. and Schirren, C. (1983) Histological evaluation of testicular biopsies. In Schirren, C. and Holstein, A.F. (eds), Fortschritte der Andrologie. Grosse Verlag, Berlin, Vol. 8, pp. 108-117.
    • (1983) Fortschritte der Andrologie , vol.8 , pp. 108-117
    • Holstein, A.F.1    Schirren, C.2
  • 17
    • 0018891414 scopus 로고
    • Demonstration of a direct carcinogenic effect of estradiol on Leydig cells of the mouse
    • Huseby, R.A. (1980) Demonstration of a direct carcinogenic effect of estradiol on Leydig cells of the mouse. Cancer Res., 40, 1006-1013.
    • (1980) Cancer Res. , vol.40 , pp. 1006-1013
    • Huseby, R.A.1
  • 18
    • 0017327754 scopus 로고
    • Lack of influence of hypophysectomy on estrogen-induced DNA synthesis in Leydig cells of BALB/c mice
    • Huseby, R.A. and Samuels, L.T. (1977) Lack of influence of hypophysectomy on estrogen-induced DNA synthesis in Leydig cells of BALB/c mice. J. Natl. Cancer Inst., 58, 1047-1049.
    • (1977) J. Natl. Cancer Inst. , vol.58 , pp. 1047-1049
    • Huseby, R.A.1    Samuels, L.T.2
  • 19
    • 0030808589 scopus 로고    scopus 로고
    • Biology of the relaxin-like factor (RLF)
    • Ivell, R. (1997) Biology of the relaxin-like factor (RLF). Rev. Reprod., 2, 133-138.
    • (1997) Rev. Reprod. , vol.2 , pp. 133-138
    • Ivell, R.1
  • 20
    • 0031160524 scopus 로고    scopus 로고
    • Relaxin-like factor: A highly specific and constitutive new marker for Leydig cells in the human testis
    • Ivell, R., Balvers, M., Domagalski, R. et al. (1997) Relaxin-like factor: a highly specific and constitutive new marker for Leydig cells in the human testis. Mol. Hum. Reprod., 3, 459-466.
    • (1997) Mol. Hum. Reprod. , vol.3 , pp. 459-466
    • Ivell, R.1    Balvers, M.2    Domagalski, R.3
  • 21
    • 0026051698 scopus 로고
    • Detection of shiga toxin-producing Shigella dysenteriae type 1 and Escherichia coli by using polymerase chain reaction with incorporation of digoxigenin-11-dUTP
    • Jackson, M.P. (1991) Detection of shiga toxin-producing Shigella dysenteriae type 1 and Escherichia coli by using polymerase chain reaction with incorporation of digoxigenin-11-dUTP. J. Clin. Microbiol., 29, 1910-1914.
    • (1991) J. Clin. Microbiol. , vol.29 , pp. 1910-1914
    • Jackson, M.P.1
  • 22
    • 0003065146 scopus 로고
    • Detection of virus in infected human tissue by in situ hybridization
    • Wilkinson, D.G. (ed.), Oxford University Press, Oxford
    • Lewis, F.A. and Wells, M. (1992) Detection of virus in infected human tissue by in situ hybridization. In Wilkinson, D.G. (ed.), In Situ Hybridization - A Practical Approach. Oxford University Press, Oxford, pp. 121-135.
    • (1992) In Situ Hybridization - A Practical Approach , pp. 121-135
    • Lewis, F.A.1    Wells, M.2
  • 23
    • 0022509111 scopus 로고
    • Direct stimulatory effects of insulin-like growth factor-I on Leydig cell steroidogenesis in primary culture
    • Lin, T., Haskell, J., Vinson, N. et al. (1986a) Direct stimulatory effects of insulin-like growth factor-I on Leydig cell steroidogenesis in primary culture. Biochem. Biophys. Res Commun., 137, 950-956.
    • (1986) Biochem. Biophys. Res Commun. , vol.137 , pp. 950-956
    • Lin, T.1    Haskell, J.2    Vinson, N.3
  • 24
    • 0022972661 scopus 로고
    • Characterization of insulin and insulin-like growth factor I receptors of purified Leydig cells and their role in steroidogenesis in primary culture: A comparative study
    • Lin, T., Haskell, I., Vinson, N. et al. (1986b) Characterization of insulin and insulin-like growth factor I receptors of purified Leydig cells and their role in steroidogenesis in primary culture: a comparative study. Endocrinology, 119, 1641-1647.
    • (1986) Endocrinology , vol.119 , pp. 1641-1647
    • Lin, T.1    Haskell, I.2    Vinson, N.3
  • 25
    • 0025153294 scopus 로고
    • Regulation of insulin-like growth factor-I messenger ribonucleic acid expression in Leydig cells
    • Lin, T., Wang, D., Harrington Calkins, J. et al. (1990) Regulation of insulin-like growth factor-I messenger ribonucleic acid expression in Leydig cells. Mol. Cell. Endocrinol., 73, 147-152.
    • (1990) Mol. Cell. Endocrinol. , vol.73 , pp. 147-152
    • Lin, T.1    Wang, D.2    Harrington Calkins, J.3
  • 26
    • 0019431341 scopus 로고
    • Increase in testis luteinizing hormone receptor by estrogen in mice susceptible to Leydig cell tumors
    • Navickis, R.J., Shimkin, M.B. and Hsueh, A.J.W. (1981) Increase in testis luteinizing hormone receptor by estrogen in mice susceptible to Leydig cell tumors. Cancer Res., 41, 1646-1651.
    • (1981) Cancer Res. , vol.41 , pp. 1646-1651
    • Navickis, R.J.1    Shimkin, M.B.2    Hsueh, A.J.W.3
  • 27
    • 0029953794 scopus 로고    scopus 로고
    • Molecular cloning and expression of the relaxin-like factor from the mouse testis
    • Pusch, W., Balvers, M. and Ivell, R. (1996) Molecular cloning and expression of the relaxin-like factor from the mouse testis. Endocrinology, 137, 3009-3013.
    • (1996) Endocrinology , vol.137 , pp. 3009-3013
    • Pusch, W.1    Balvers, M.2    Ivell, R.3
  • 28
    • 0028852116 scopus 로고
    • Relaxin-induced deoxyribonucleic acid synthesis in porcine granulosa cells is mediated by insulin-like growth factor-I
    • Oleth, K.M. and Bagnell, C.A. (1995) Relaxin-induced deoxyribonucleic acid synthesis in porcine granulosa cells is mediated by insulin-like growth factor-I. Biol. Reprod., 53, 1286-1292.
    • (1995) Biol. Reprod. , vol.53 , pp. 1286-1292
    • Oleth, K.M.1    Bagnell, C.A.2
  • 29
    • 0030755474 scopus 로고    scopus 로고
    • Relaxin increases insulin-like growth factors (IGFs) and IGF-binding proteins of the pig uterus in vivo
    • Oleth, K.M., Lenhart, I.A., Ryan, P.L. et al. (1997) Relaxin increases insulin-like growth factors (IGFs) and IGF-binding proteins of the pig uterus in vivo. Endocrinology, 138, 3652-3658.
    • (1997) Endocrinology , vol.138 , pp. 3652-3658
    • Oleth, K.M.1    Lenhart, I.A.2    Ryan, P.L.3
  • 30
    • 0029973603 scopus 로고    scopus 로고
    • Relaxin binds to and elicits a response from cells of the human monocytic cell line, THP-1
    • Parsell, D.A., Mak, J.Y. Amento, E.P. et al. (1996) Relaxin binds to and elicits a response from cells of the human monocytic cell line, THP-1. J. Biol. Chem., 271, 27936-27941.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27936-27941
    • Parsell, D.A.1    Mak, J.Y.2    Amento, E.P.3
  • 31
    • 0028843245 scopus 로고
    • The human leydig insulin-like (hLey I-L) gene is expressed in the corpus luteum and trophoblast
    • Tashima, L.S., Hieber, A.D., Greenwood, F.C. et al. (1995) The human leydig insulin-like (hLey I-L) gene is expressed in the corpus luteum and trophoblast. J. Clin. Endocrinol. Metab., 80, 707-710.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 707-710
    • Tashima, L.S.1    Hieber, A.D.2    Greenwood, F.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.