A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae

Molecular and General Genetics

Volumn 260, Issue 6, 1999, Pages 535-540

  Sato, T ^a,b   Jigami, Y ^a,b   Suzuki, T ^c   Uemura, H ^a  

^a Ministry of International Trade and Industry   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c UTSUNOMIYA UNIVERSITY   (Japan)

Author keywords

GCR; Gene expression; Glycolysis; Saccharomyces cerevisiae

Indexed keywords

GLYCOLYTIC ENZYME; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; BRAIN; CONTROLLED STUDY; DNA LIBRARY; ENZYME ACTIVITY; FUNGUS GROWTH; FUNGUS MUTANT; GENE EXPRESSION REGULATION; GENE ISOLATION; GENETIC COMPLEMENTATION; GLYCOLYSIS; HEART; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; MUSCLE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPORTER GENE; SACCHAROMYCES CEREVISIAE;

DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC COMPLEMENTATION TEST; GLYCOLYSIS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TISSUE DISTRIBUTION; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS;

EID: 0032902810     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050926     Document Type: Article

References (21)

1. Baker HV (1986) Glycolytic gene expression in Saccharomyces cerevisiae: nucleotide sequence of GCRI, null mutants, and evidence for expression. Mol Cell Biol 6:3774-3784
2. Brendel V, Karlin S (1989) Association of charge clusters with functional domains of cellular transcription factors. Proc Natl Acad Sci USA 86:5698-5702
3. Buratowsky S, Hahn S, Sharp PA, Guarente L (1988) Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature 334:37-42
4. Chien C-T, Bartel PL, Sternglanz R, Fields S (1991) The two hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc Natl Acad Sci USA 88:9578-9582
5. Chodosh LA, Olesen J, Hahn S, Baldwin AS, Guarente L, Sharp PA (1988) A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable. Cell 53:25-35
6. Clontech (1997) Housekeeping RT-PCR amplimers and cDNA probes. CLONTECHniques 12:15-16
7. Fraenkel DG (1982) Carbohydrate metabolism. In: Strathern JN, Jones EW, Broach JR. (eds) The molecular biology of the yeast Saccharomyces: metabolism and gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp 1-37
8. Gill G, Ptashne M (1987) Mutants of GAL4 protein altered in an activation function. Cell 51:121-126
9. Hope IA, Struhl K (1986) Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast. Cell 46:885-894
10. Huie MA, Scott EW, Drazinic CM. Lopez MC, Hornstra IK, Yang TP, Baker HV (1992) Characterization of the DNA-binding activity of GCR1: in vivo evidence for two GCR1-binding sites in the upstream activating sequence of TPI of Saccharomyces cerevisiae. Mol Cell Biol 12:2690-2700
11. Lupas A (1996) Prediction and analysis of coiled-coil structures. Methods Enzymol 266:513-525
12. Ma J, Ptashne M (1987) A new class of yeast transcriptional activators. Cell 51:113-119
13. Maity SN, Vuorio T, Crombrugghe B (1990) The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor. Proc Natl Acad Sci USA 84:3648-3652
14. Sherman F, Fink GR, Hicks JB (1986) Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
15. Shore D (1994) RAP1: a protean regulator in yeast. Trends Genet 10:408-412
16. Simon B, Tillotson L, Brand SJ (1994) Activation of gastrin gene transcription in islet cells by a RAP1-like cis-acting promoter clement. FEBS Lett 351:340-344
17. Uemura H, Fraenkel DG (1990) gcr2, a new mutation affecting glycolytic gene expression in Saccharomyces cerevisiae. Mol Cell Biol 10:6389-6396
18. Uemura H, Jigami Y (1992) Role of GCR2 in transcriptional activation of yeast glycolytic genes. Mol Cell Biol 12:3834-3842
19. Uemura H, Jigami Y (1995) Mutation in GCRI, a transcriptional activator of Saccharomyces cerevisiae glycolytic genes, function as suppressors of gcr2 mutations. Genetics 139:511-521
20. Uemura H, Koshio M, Inoue Y, Lopez MC, Baker HV (1997) The role of Gcrlp in the transcriptional activation of glycolytic genes in yeast Saccharomyces cerevisiae. Genetics 147:521-532
21. Vernet T, Dignard D, Thomas DY (1987) A family of yeast expression vectors containing the phage fl intergenic region. Gene 52:225-233