Infectivity of Cryptosporidium parvum in healthy adults with pre- existing anti-C. parvum serum immunoglobulin G

American Journal of Tropical Medicine and Hygiene

Volumn 60, Issue 1, 1999, Pages 157-164

  Chappell, Cynthia L ^a   Okhuysen, Pablo C ^b   Sterling, Charles R ^c   Wang, Constance ^a   Jakubowski, Walter ^d   Dupont, Herbert L ^e  

^a UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e ST LUKE S EPISCOPAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; PROTOZOON ANTIBODY;

ADULT; ARTICLE; CONTROLLED STUDY; CRYPTOSPORIDIOSIS; CRYPTOSPORIDIUM PARVUM; DIARRHEA; FECES ANALYSIS; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; NORMAL HUMAN; OOCYST;

CRYPTOSPORIDIUM PARVUM; PROTOZOA;

EID: 0032902683     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1999.60.157     Document Type: Article

References (38)

1. Goldstein ST, Juranek DD, Ravenholt O, Hightower AW, Martin DG, Mesnik JL, Griffiths SD, Bryant AJ, Reich RR, Herwaldt BL, 1996. Cryptosporidiosis: an outbreak associated with drinking water despite state-of-the-art water treatment. Ann Intern Med 124: 459-468.
2. Hayes EB, Matte TD, O'Brien TR, McKinley TW, Logsdon GS, Rose JB, Ungar BLP, Word DM, Pinsky PF, Cummings ML, Wilson MA, Long EG, Hurwitz ES, Juranek DD, 1989. Large community outbreak of cryptosporidiosis due to contamination of a filtered public water supply. N Engl J Med 320: 1372-1376.
3. MacKenzie WR, Hoxie NJ, Proctor ME, Gradus MS, Blair KA, Peterson DE, Kazmierczak JJ, Addiss DG, Fox KR, Rose JB, Davis JP, 1994. A massive outbreak in Milwaukee of Cryptaxparidium infection transmitted through the public water supply. N Engl J Med 331: 161-167.
4. Petersen, C, 1992. Cryptosporidiosis in patients infected with the human immunodeficiency virus. Clin Infect Dis 15: 903-909.
5. Centers for Disease Control and Prevention, 1994. Addressing Emerging Infectious Disease Threats. A Prevention Strategy for the United States. Atlanta, GA: U.S. Department of Health and Human Services. Public Health Service.
6. Ernest JA, Blagburn BL, Lindsay DS, 1986. Infection dynamics of Cryptosporidium parvum (Apicomplexa: Cryptosporidiidae) in neonatal mice (Mus musculus). J Parasitol 72: 796-798.
7. Harp JA, Woodmansee DB, Moon HW, 1990. Resistance of calves to Cryptosporidium parvum: effects of age and previous exposure. Infect Immun 58: 2237-2240.
8. Miller R, Bronsdon M, Morton W, 1990. Experimental cryptosporidiosis in a primate model. J Infect Dis 161: 312-315.
9. Chappell CL, Okhuysen PC, Sterling CR, DuPont HL, 1996. Cryptosporidium parvum: intensity of infection and oocyst excretion patterns in healthy volunteers. J Infect Dis 173: 232-236.
10. Okhuysen PC, Chappell CL, Sterling CR, Jakubowski W, DuPont HL, 1998. Susceptibility and serologic response of healthy adults to reinfection with Cryptosporidium parvum. Infect Immun 66: 441-443.
11. Arnault I, Reperant J, Naciri M, 1994. Humoral antibody response and oocyst shedding after experimental infection of histocompatible newborn and weaned piglets with Cryptosporidium parvum. Vet Res 25: 371-383.
12. Moon HW, Woodmansee DB, Harp JA, Abel S, Ungar BLP, 1988. Lacteal immunity to enteric cryptosporidiosis in mice: immune dams do not protect their suckling pups. Infect Immun 56: 649-653.
13. Ortega-Mora L, Troncoso J, Rojo-Vazquez F, Gomez-Bautista M, 1993. Serum antibody response in lambs naturally and experimentally infected with Cryptospuridium parvum. Vet Parasitol 50: 45-54.
14. Peeters J, Villacorta I, Vanopdenbosch E, Vandergheynst D, Naciri M, Ares-Mazas E, Yvore P, 1992. Cryptosporidium parvum in calves: kinetics and immunoblot analysis of specific serum and local antibody responses (immunoglobulin A [IgA], IgG, and IgM) after natural and experimental infections. Infect Immun 60: 2309-2316.
15. Whitmire W, Harp J, 1991. Characterization of bovine cellular and serum antibody responses during infection by Cryptosporidium parvum. Infect Immun 59: 990-995.
16. Casemore D, Jessop EG, Douce D, Jackson FB, 1986. Cryptosporidium plus camplyobacter [sic]: an outbreak in a semi-rural population. J Hyg 96: 95-105.
17. Moss DM, Bennett SN, Arrowood MJ, Hurd MR, Lammie PJ, Wahlquist SP, Addiss DG, 1994. Kinetic and isotypic analysis of specific immunoglobulins from crew members with cryptosporidiosis on a U.S. Coast Guard cutter. J Eukaryot Microbiol 41: 52S-55S.
18. Newman RD, Zu S-X, Wuhib T, Lima AAM, Guerrant RL, Sears CL, 1994. Household epidemiology of Cryptosporidium parvum infection in an urban community in northeast Brazil. Ann Intern Med 120: 500-505.
19. Ungar BLP, Soave R, Fayer R, Nash TE, 1986. Enzyme immunoassay detection of immunoglobulin M and G antibodies to Cryptosporidium in immunocompetent and immunocompromised persons. J Infect Dis 153: 570-577.
20. DuPont HL, Chappell CL, Sterling CR, Okhuysen PC, Rose JB, Jakubowski W, 1995. The infectivity of Cryptosporidium parvum in healthy volunteers. N Engl J Med 332: 855-859.
21. Reed LJ, Muench H, 1938. A simple method of estimating fifty per cent endpoints. Am J Hyg 27: 493-497.
22. Ungar, BLP, 1990. Cryptosporidiosis in humans (Homo sapiens). Dubey JP, Speer CA, Fayer R, eds. Cryptosporidiosis of Man and Animals. Boca Raton, FL: CRC Press, Inc., 59-82.
23. Current WL, 1983. Human cryptosporidosis in immunocompetent and immunodeficient persons: studies of an outbreak and experimental transmission. N Engl J Med 308: 1252-1257.
24. Weisburger WR, Hutcheon DF, Yardley JH, Roche JC, Hillis WD, Charache P, 1979. Cryptosporidiosis in an immunosuppressed renal-transplant recipient with IgA deficiency. Am J Clin Pathol 72: 473-478.
25. Tzipori S, Roberton D, Chapman C, 1986. Remission of diarrhea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum. Br Med J 293: 1276-1277.
26. Ungar BLP, Ward D, Fayer R, Quinn C, 1990. Cessation of Cryptosporidium-associated diarrhea in an acquired immunodeficiency syndrome patient after treatment with hyperimmune bovine colostrum. Gastroenterology 98: 486-489.
27. Greenberg PD, Cello JP, 1996. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 13: 348-354.
28. Okhuysen PC, Chappell CL, Crabb J, Valdez LM, Douglass E, DuPont HL, 1998. Prophylactic effect of bovine anti-Cryptosporidium hyperimmune colostrum in healthy volunteers challenged with Cryptosporidium parvum. Clin Infect Dis 22: 1324-1329.
29. Taghi-Kilani R, Sekla L, Hayglass KT, 1990. The role of humoral immunity in Cryptosporidium spp. infection. Studies with B cell-depleted mice. J Immunol 145: 1571-1576.
30. Cozon G, Biron F, Jeannin M, Cannella D, Revillard J-P, 1994. Secretory IgA antibodies to Cryptosporidium parvum in AIDS patients with chronic cryptosporidiosis. J Infect Dis 169: 696-699.
31. DuPont H, Ericsson CD, Mathewson JJ, de la Cabada FJ, Conrad DA, 1992. Oral aztreonam, a poorly absorbed yet effective therapy for bacterial diarrhea in US travelers to Mexico. JAMA 267: 1932-1935.
32. Valdez LM, Dang H, Okhuysen PC, Chappell CL, 1997. Flow cytometric detection of Cryptosporidium oocysts in human stool samples. J Clin Microbiool 35: 2013-2017.
33. Perz JF, Ennever FK, Le Blancq SM, 1998. Cryptosporidium in tap water. Comparison of predicted risks with observed levels of disease. Am J Epidemiol 147: 289-301.
34. Udezulu IA, Visvesvara GS, Moss DM, Leitch GJ, 1992. Isolation of two Giardia lamblia (WB strain) clones with distinct surface protein and antigenic profiles and differing infectivity and virulence. Infect Immun 60: 2274-2280.
35. Bonnin A, Fourmaux MN, Dubremetz JF, Nelson RG, Gobet P, Harly G, Buisson M, Puygauthier-Tobas D, Gabriel-Pospisil F, Naciri M, Camerlynck P, 1996. Genotyping human and bovine isolates of Cryptosporidium parvum by polymerase chain reaction-restriction fragment length polymorphism analysis of a repetitive DNA sequence. FEMS Microbiol Lett 137: 207-211.
36. Spano F, Putignani L, McLauchlin J, Casemore DP, Crisanti A, 1997. PCR-RFLP analysis of the Cryptosporidium oocyst wall protein (COWP) gene discriminates between C. wrairi and C. parvum, and between C. parvum isolates of human and animal origin. FEMS Microbiol Lett 150: 209-217.
37. Carraway M, Tzipori S, Widmer G, 1997. A new restriction fragment length polymorphism from Cryptosporidium parvum identifies genetically heterogeneous parasite population and genotypic changes following transmission from bovine to human hosts. Infect Immun 65: 3958-3960.
38. Murphy, B, 1994. Mucosal immunity to viruses. Ogra PL, Mestecky J, Lamm M, Strober W, McGhee JR, Bienenstock J, eds. Handbook of Mucosal Immunology. San Diego, CA: Academic Press, Inc., 333-343.