Gilvusmycin, a new antitumor antibiotic related to CC-1065

Journal of Antibiotics

Volumn 52, Issue 3, 1999, Pages 263-268

  Tokoro, Yusuke ^a   Isoe, Toshiyuki ^a   Shindo, Kazutoshi ^a  

^a KIRIN BREWERY CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; GILVUSMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBIOTIC BIOSYNTHESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; LEUKEMIA P 388; LEUKEMIA P 388 CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES;

STREPTOMYCES;

EID: 0032902641     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.263     Document Type: Article

References (5)

1. REYNOLDS, V. L.; J. P. MCGOVREN & L. H. HURLEY: The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic. J. Antibiotics 39: 319-334, 1986
2. SHIRLING, E. B. & D. GOTTLIEB: Methods for characterization of Streptomyces species. Int. J. Syst. Bacteriol. 16: 313-340, 1966
3. FROLOVA, V. I.; A. D. KUZOVKOV, A. I. CHERNYSHEV, M. M. TAIG & L. P. IVANITSKAIA: Identification of the antibiotic formed by a Streptomyces canulus 106/78 culture with antibiotic CC-1065. Antibiotiki 27: 483-487, 1982
4. MARTIN, D. G.; C. BILES, S. A. GERPHEIDE, L. J. HANKA, W. C. KRUEGER, J. P. MCGOVREN, S. A. MIZSAK, G. L. NEIL, J. C. STEWART & J. VISSER: CC-1065 (NSC 298223), a potent new antitumor agent improved production and isolation, characterization and antitumor activity. J. Antibiotics 34: 1119-1125, 1981
5. 13C assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMR. J. Am. Chem. Soc. 108: 2093-2094, 1986