Regioselective synthesis and biological profiling of butyric and phenylalkylcarboxylic esters derivated from D-mannose and xylitol: Influence of alkyl chain length on acute toxicity

European Journal of Pharmaceutical Sciences

Volumn 7, Issue 2, 1999, Pages 93-106

  Pouillart, Philippe ^a,d   Douillet, Olivier ^a   Scappini, Barbara ^b   Antonella Gozzini, ^b   Santini, Valeria ^b   Grossi, Alberto ^b   Pagliai, Gabriella ^b   Strippoli, Pierluigi ^c   Rigacci, Luigi ^b   Ronco, Gino ^a   Villa, Pierre ^a  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d CAFISAP Porcine Biomedical Center   (France)

Author keywords

Anticancer; Butyric acid; Hemoglobinopathies; Monosaccharide esters transesterification; Prodrugs; Toxicity

Indexed keywords

ANTIMITOTIC AGENT; BUTYRIC ACID DERIVATIVE; ESTER; FATTY ACID ESTER;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SYNTHESIS; DRUG TOXICITY; ENANTIOMER; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRAVENOUS DRUG ADMINISTRATION; LEUKEMIA CELL; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BUTYRIC ACIDS; FEMALE; HUMANS; MALE; MANNOSE; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; XYLITOL;

EID: 0032902038     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(98)00011-6     Document Type: Article

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