Effects of adenosine infusion on gastric emptying in healthy volunteers

Acta Anaesthesiologica Scandinavica

Volumn 43, Issue 1, 1999, Pages 87-90

  Forsberg, C ^a   Sollevi, A ^a   Thorn S E ^b   Segerdahl, M ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b ÖREBRO MEDICAL CENTRE HOSPITAL   (Sweden)

Author keywords

Acetaminophen; Adenosine; Gastric motility; Humans

Indexed keywords

ADENOSINE; PARACETAMOL; PLACEBO;

ADULT; ANTINOCICEPTION; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFECT; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH EMPTYING; STOMACH MOTILITY;

ABSORPTION; ACETAMINOPHEN; ADENOSINE; ADMINISTRATION, ORAL; ADULT; ANALGESICS; ANALGESICS, NON-NARCOTIC; AREA UNDER CURVE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EATING; GASTRIC EMPTYING; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PLACEBOS; TIME FACTORS;

EID: 0032901150     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.1999.430118.x     Document Type: Article

References (27)

1. 1. Kehlet H. Surgical stress: The role of pain and analgesia. Br J Anaesth 1989: 63: 189-195.
2. 2. Thörn S-E, Wattwil M, Näslund I. Postoperative epidural morphine, but not epidural bupivacaine, delays gastric emptying on the first day after cholecystectomy. Reg Anesth 1992: 17: 91-94.
3. 3. Thörn S-E, Wattwil M, Lindberg G, Säwe J. Systemic and central effects of morphine on gastroduodenal motility. Acta Anaesthesiol Scand 1996: 40: 177-186.
4. 4. Sollevi A. Cardiovascular effects of adenosine in man; possible clinical implications. Progr Neurobiol 1986: 27: 319-349.
5. 5. Segerdahl M, Ekblom A, Sollevi A. The influence of adenosine, ketamine and morphine on experimentally induced ischemic pain in healthy volunteers. Anesth Analg 1994: 79: 787-791.
6. 6. Segerdahl M, Ekblom A, Sjölund K-F, Belfrage M, Forsberg C, Sollevi A. Systemic adenosine attenuates touch evoked allodynia induced by mustard oil in humans. Neuroreport 1995: 6: 753-756.
7. 7. Segerdahl M, Ekblom A, Sandelin K, Wickman M, Sollevi A. Peroperative adenosine infusion reduces the requirements for isoflurane and postoperative analgesics. Anesth Analg 1995: 80: 1145-1149.
8. 8. Segerdahl M, Irestedt L, Sollevi A. Antinociceptive effect of perioperative adenosine infusion in abdominal hysterectomy. Acta Anaesthesiol Scand 1997: 41: 473-479.
9. 9. Belfrage M, Sollevi A, Segerdahl M, Sjölund K-F, Hansson P. Systemic adenosine infusion alleviates spontaneous and stimulus evoked pain in patients with peripheral neuropathic pain. Anesth Analg 1995: 81: 713-717.
10. 10. Fredholm B. Adenosine receptors in the central nervous system. News Physiol Sci 1995: 10: 122-128.
11. 11. Sawynok J, Sweeney MI. The role of purines in nociception. Neuroscience 1989: 32: 557-569.
12. 12. Heading RC, Nimmo J, Prescott LF, Tothill P. The dependence of paracetamol absorption on the rate of gastric emptying. Br J Pharmacol 1973: 47: 415-421.
13. 13. Clements JA, Heading RC, Nimmo WS, Prescott LF. Kinetics of acetaminophen and gastric emptying in man. Clin Pharmacol Ther 1978: 24: 420-431.
14. 14. Clyburn PA, Rosen M. Oral controlled-release morphine and gut function. Eur J Anaesthesiol 1989: 6: 347-353.
15. 15. Thörn S-E, Wattwil M, Källander A. Effects of epidural morphine and epidural bupivacaine on gastroduodenal motility during the fasted state and after food intake. Acta Anaesthesiol Scand 1994: 38: 57-62.
16. 16. Ingram DM, Sheiner HJ. Postoperative gastric emptying. Br J Surg 1981: 68: 572-576.
17. 17. Code CF, Marlett JA. The interdigestive myoelectric complex of the stomach and small bowel of dogs. J Physiol 1975: 246: 289-309.
18. 18. Kellow JE, Borody TJ, Phillips SF, Tucker RL, Haddad AC. Human interdigestive motility, variations in pattern from esophagus to colon. Gastroenterology 1986: 91: 386-395.
19. 19. Grundy D. The integration of physiological mechanism. In: Gastrointestinal motility. Lancaster/Boston: MTP Press Limited, 1985: 145-160.
20. 20. Asai T, McBeth C, Stewart JI, Williams J, Vaughan RS, Power I. Effect of clonidine on gastric emptying of liquids. Br J Anaesth 1997: 78: 28-33.
21. 21. Hutson W, Roehrkasse R, Wald A. Influence of gender and menopause on gastric emptying and motility. Gastroenterology 1989: 96: 11-17.
22. 2b receptors coupled to distinct interactive signaling pathways in intestinal muscle cells. J Pharmacol Exp Ther 1995: 274: 300-306.
23. 23. Fargeas MJ, Fioramonti J, Bueno L. Central and peripheral actions of adenosine and its analogues on intestinal myoelectric activity and propulsions in rats. J Gastroint Motility 1990: 2: 121-127.
24. 1-receptor on defecation, small intestinal propulsion and gastric emptying in rats. Jpn J Pharmacol 1995: 68: 119-123.
25. 25. Watt AH, Lewis DJM, Horne JJ, Smith PM. Reproduction of epigastric pain of duodenal ulceration by adenosine. Br Med J 1987: 294: 10-12.
26. 26. Bleehen T, Keele CA. Observations on the algogenic actions of adenosine compounds on the human blister base preparation. Pain 1977: 3: 367-377.
27. 27. Sylvén C, Beerman B, Jonzon B, Brandt R. Angina pectoris-like pain provoked by intravenous adenosine in healthy volunteers. Br Med J 1986: 293: 227-230.