The effects of subanesthetic concentrations of sevoflurane and nitrous oxide, alone and in combination, on analgesia, mood, and psychomotor performance in healthy volunteers

Anesthesia and Analgesia

Volumn 88, Issue 5, 1999, Pages 1149-1154

  Janiszewski, Debra J ^a   Galinkin, Jeffrey L ^a   Klock, P Allan ^a   Coalson, Dennis W ^a   Pardo, Helene ^a   Zacny, James P ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITROUS OXIDE; SEVOFLURANE;

ADULT; ANESTHESIA MECHANISM; AROUSAL; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; FEMALE; GENERAL ANESTHESIA; HUMAN; HUMAN EXPERIMENT; INHALATIONAL DRUG ADMINISTRATION; MALE; MOOD; NEUROCHEMISTRY; NEUROMODULATION; NOCICEPTION; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; SELF REPORT; SMELLING; SOMNOLENCE;

ADULT; AFFECT; ANALGESIA; ANESTHETICS, COMBINED; ANESTHETICS, INHALATION; CROSS-OVER STUDIES; FEMALE; HUMANS; MALE; METHYL ETHERS; NITROUS OXIDE; PSYCHOMOTOR PERFORMANCE;

EID: 0032900478     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199905000-00034     Document Type: Article

References (29)

1. Rampil IJ, Lockhart SH, Eger EI II, et al. The electroencephalographic effects of desflurane in humans. Anesthesiology 1991; 74:434-9.
2. Roald OK, Forsman M, Heier MS, Steen PA. Cerebral effects of nitrous oxide when added to low and high concentrations of isoflurane in the dog. Anesth Analg 1991;72:75-9.
3. Yli-Hankala A, Lindgren L, Porkkala T, Jantti V. Nitrous oxide-mediated activation of the EEG during isoflurane anaesthesia in patients. Br J Anaesth 1993;70:54-7.
4. Porkkala T, Jantti V, Kaukinen S, Hakkinen V. Nitrous oxide has different effects on the EEG and somatosensory evoked potentials during isoflurane anesthesia in patients. Acta Anaesthesiol Scand 1997;41:497-501.
5. Utsumi J, Adachi T, Kurata J, et al. Effect of xenon on central nervous system electrical activity during sevoflurane anaesthesia in cats: comparison with nitrous oxide. Br J Anaesth 1998; 80:628-33.
6. Katoh T, Ikeda K, Bito H. Does nitrous oxide antagonize sevoflurane-induced hypnosis? Br J Anaesth 1997;79:465-8.
7. Chortkoff BS, Bennett HL, Eger EI II. Does nitrous oxide antagonize isoflurane-induced suppression of learning? Anesthesiology 1993;79:724-32.
8. Goto T, Marota JJ, Crosby G. Volatile anaesthetics antagonize nitrous oxide and morphine-induced analgesia in the rat. Br J Anaesth 1996;76:702-6.
9. Zacny JP, Yajnik S, Lichtor JL, et al. The acute and residual effects of subanesthetic concentrations of isoflurane/nitrous oxide combinations on cognitive and psychomotor performance in healthy volunteers. Anesth Analg 1996;82:153-7.
10. Derogatis LR, Lipman RS, Covi L. SCL-90. An outpatient psychiatric rating scale-preliminary report. Psychopharmacol Bull 1973;9:13-7.
11. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association, 1987.
12. Chen ACN, Dworkin SF, Huag J. Human pain responsivity in a tonic pain model: physiological determinants. Pain 1989;37: 143-60.
13. Melzak R. The short-form McGill Pain Questionnaire. Pain 1987; 30:191-7.
14. Glass PS, Bloom M, Kearse L, et al. Bispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane, and alfentanil in healthy volunteers. Anesthesiology 1997; 86:836-47.
15. Wechsler D. The measurement and appraisal of adult intelligence. Baltimore: Williams & Wilkins, 1958.
16. Wilcox RR. Statistics for the social sciences. San Diego: Academic, 1996:246-8.
17. Goto T, Marota JA, Crosby G. Nitrous oxide induces preemptive analgesia in the rat that is antagonized by halothane. Anesthesiology 1994;80:409-16.
18. Komatsu T, Shingu K, Tomemori N, et al. Nitrous oxide activates the supraspinal pain inhibition system. Acta Anaesthesiol Scand 1981;25:519-22.
19. Tomi K, Mashimo T, Tashiro C, et al. Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans. Br J Anaesth 1993;70:684-6.
20. Galinkin JL, Janiszewski DJ, Young CJ, et al. Subjective, psychomotor, cognitive, and analgesic effects of subanesthetic concentrations of sevoflurane and nitrous oxide. Anesthesiology 1997;87:1082-8.
21. Zacny JP, Sparacino G, Hoffmann PM, et al. The subjective, behavioral and cognitive effects of subanesthetic concentrations of isoflurane and nitrous oxide in healthy volunteers. Psychopharmacology (Berl) 1994;114:409-16.
22. Dohrn CS, Lichtor JL, Coalson DW, et al. Reinforcing effects of extended inhalation of nitrous oxide in humans. Drug Alcohol Depend 1993;31:265-80.
23. Zacny JP, Lichtor JL, Coalson DW, et al. Examining the subjective, psychomotor-impairing, and reinforcing effects of nitrous oxide in healthy volunteers: a dose-response analysis. Behav Pharmacol 1996;7:194-9.
24. Saidman LJ, Eger EI II. Effect of nitrous oxide and of narcotic premedication on the alveolar concentration of halothane required for anesthesia. Anesthesiology 1964;25:302-6.
25. Murakawa M, Adachi T, Nakao S, et al. Activation of the cortical and medullary dopaminergic systems by nitrous oxide in rats: a possible neurochemical basis for psychotropic drug effects and postanesthetic nausea and vomiting. Anesth Analg 1994;78: 376-81.
26. Karuri AR, Kugel G, Engelking LR, Kumar MSA. Alterations in catecholamine turnover in specific regions of the rat brain following acute exposure to nitrous oxide. Brain Res Bull 1998;45: 557-61.
27. Shichino T, Murakawa M, Adachi T, et al. Effects of inhalation anaesthetics on the release of acetylcholine in the rat cerebral cortex in vivo. Br J Anaesth 1998;80:365-70.
28. Ebert TJ, Kampine JP. Nitrous oxide augments sympathetic outflow: direct evidence from human peroneal nerve endings. Anesth Analg 1989;69:444-9.
29. Mori K, Winters WD. Neural background of sleep and anesthesia. Int Anesthesiol Clin 1975;13:67-108.