The antiplatelet activity of Escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway

European Journal of Haematology

Volumn 62, Issue 5, 1999, Pages 317-326

  Sheu, Joen Rong ^a   Hung, W C ^a   Su, C H ^a   Lin, C H ^a   Lee, L W ^a   Lee, Y M ^b   Yen, M H ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Cyclic GMP; Intracellular calcium mobilization; LPS; Nitric oxide; Platelet aggregation

Indexed keywords

CALCIUM ION; CYCLIC GMP; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHORBOL DIBUTYRATE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; DOSE RESPONSE; ENDOTOXEMIA; ESCHERICHIA COLI; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; SEPTICEMIA; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION INHIBITION;

EID: 0032899926     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1999.tb01909.x     Document Type: Article

References (36)

1. Beller FK. The role of endotoxin in disseminated intravascular coagulation. Thromb Diath Haemorrh 1969;36:125 149.
2. Rau L, Keane WF, Michael AF. Unilateral shwartzman reaction: Cortical necrosis in one kidney following in vivo perfusion with endotoxin. Kidney Int 1977;12:91-95.
3. Bone RC. The pathogenesis of sepsis. Ann Intern Med 1991;115:457-469.
4. Davis RB, Meeker WR, McQuarrie DG. Immediate effects of intravenous endotoxin on serotonin concentrations and blood products. Circulation Res 1960;8:234-239.
5. Des Pres RM, Horowitz HI, Hook EW. Effects of bacterial endotoxin on rabbit platelets, I. Platelet aggregation and release of platelet factors in vitro. J Exp Med 1967;114:857-873.
6. Matera C, Falzarano C, Berrino L, Rossi F. Effects of tetanus toxin, Salmonella typhimurium porin, and bacterial lipopolysaccharide on platelet aggregation. J Med 1992;23:327-338.
7. Isogai E, Kitagawa H, Isogai H, et al. Effects of leptospiral lipopolysaccharide on rabbit platelets. Int J Med Microbiol 1992;271:186-196.
8. Corn M. Effect of thrombin, ADP, connective tissue and endotoxin on platelet glycolysis. Nature (London) 1966;212:508.
9. Mueller-Eckhardt CH, Luscher EF. Immune reactions of human blood platelets. IV. Investigators on the problem of an immunologically induced effect of endotoxin on human platelets. Thromb Diath Haemorrh 1968;20:336-344.
10. Saba HI, Sara SR, Morelli G, Hartmann RG. Endotoxinmediated inhibition of human platelet aggregation. Thromb Res 1984;34:19-33.
11. Ream VI, Deykin E, Gurewich V, Wessler S. The aggregation of human platelets by bacterial endotoxin. J Lab Clin Med 1965;66:245-252.
12. Nagayama M, Zucker MB, Beller FK. Effects of a variety of endotoxins on human and rabbit platelet function. Thromb Diath Haemorrh 1971;26:467-473.
13. Baba K. Effects of E. coli LPS on human platelet aggregation. Jpn J Anesthesiol 1994;43:339-345.
14. Huang TF, Sheu JR, Teng CM. A potent antiplatelet peptide, triflavin, from trimeresurus flavoviridis snake venom. Biochem J 1991;277:351-357.
15. Teng CM, Chen WY, Ko WC, Ouyang C. Antiplatelet effect of butylindenephthaline. Biochim Biophys Acta 1987;924:375-383.
16. Born GVR, Cross MJ. The aggregation of blood platelets. J Physiol 1963;168:178-195.
17. Sheu JR, Teng CM, Huang TF. Triflavin, an RGD-containing antiplatelet peptide, binds to GP IIIa of ADP-stimulated platelets. Biochem Biophys Res Commun 1992;189:1236 1242.
18. Sheu JR, Lin Ch, Peng CH, Huang TF. Triflavin, an Arg-Gly-Asp-containing peptide, inhibits the adhesion of tumor cells to matrix protein via binding to multiple integrin receptors expressed on human hepatoma cells. Proc Soc Exp Biol Med 1996;213:71-79.
19. Lowry DH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951;193:265-275.
20. 2+ induces with greatly improved fluorescence properties. J Biol Chem 1985;260:3440-3450.
21. Karniguian A, Legrand YJ, Caen JP. Prostaglandins: Specific inhibition of platelet adhesion to collagen and relationship with c AMP level, Prostaglandin 1982;23:437-457.
22. Wroblewski F, Ladue JS. Lactic dehydrogenase activity in blood. Proc Soc Exp Biol Med 1955;90:210-215.
23. Salvemini D, Denucci G, Gryglewski RJ, Vanf JR. Human neutrophils and mononuclear cells inhibits platelet aggregation by releasing a nitric oxide-like factor. Proc Natl Acad Sci USA 1989;86:6328-6332.
24. Mollace V, Salvemini D, Anggard E, Vanf JR. Nitric oxide from vascular smooth muscle cells: Regulation of platelet reactivity and smooth muscle cell guanylate cyclase. Br J Pharmacol 1991;104:633-639.
25. Mehta JL, Chen LY, Mehta P. Identification of constitutive and inducible forms of nitric oxide synthase in human platelets. J Lab Clin Med 1995;25:753-760.
26. Siess W, Lapetina EG. Platelet aggregation induced by alpha 2-adrenoceptor and protein kinase C activation. A novel synergism. Biochem J 1989;263:377-385.
27. Yen MH, Liu YC, Hong HJ, Sheu JR, Wu CC. Role of nitric oxide in lipopolysaccharide-induced mortality from spontaneously hypertensive rats. Life Sci 1997;60:1223-1230.
28. Charo IF, Feinman RD, Detwiler TC. Inhibition of platelet secretion by an antagonist of intracellular calcium. Biochem Biolphys Res Commun 1976;72:1462-1467.
29. 2+ in platelets is controlled by cyclic AMP: Antagonism between stimulators and inhibitors of adenylate cyclase. Biochem Biophys Res Commun 1984;120:579- 585.
30. Radomski MW, Palmer RJ, Moncada S. An L-arginine to nitric oxide pathway in human platelets regulates aggregation. Proc Natl Acad Sci USA 1990;87:5139-5197.
31. McDonald LJ, Murad F. Nitric oxide and cyclic GMP signaling. Proc Soc Exp Biol Med 1996;211:1-6.
32. Garbers DL. Guanylyl cyclase receptors and their endocrine, paracrine, and autocrine ligands. Cell 1992;71:1-4.
33. Murohara T, Parkinson SJ, Waldman SA, Lefer AM, Inhibition of nitric oxide biosynthesis promotes P-selectin expression in platelets. Role of protein kinase C. Arterioscl Thromb Vas Biol 1995;15:2068-2075.
34. 2+, phospholipid-dependent protein kinase associated with plasma membrane. Nature (London) 1983;301:621-623.
35. Neame PB, Kelton JG, Walker IR, Stewart IO, Nossel HL, Hirsch J. Thrombocytopenia in septicemia: The role of disseminated intravascular coagulation. Blood 1980;56:88-92.
36. Bhargava M, Kumari S, Bhargava SK. Impairment of platelet function in neonatal septicemia. Indian J Med Res 1978;68:964-969.