Molecular fine-specificity analysis of antibody responses to human cytomegalovirus and design of novel synthetic-peptide-based serodiagnostic assays

Journal of Clinical Microbiology

Volumn 37, Issue 1, 1999, Pages 179-188

  Greijer, Astrid E ^a   Van De Crommert, Jos M G ^a   Stevens, Servi J C ^a   Middeldorp, Jaap M ^a  

^a Organon Teknika   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; EPITOPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; SYNTHETIC PEPTIDE; VIRUS ANTIGEN; VIRUS PROTEIN;

ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KIDNEY ALLOGRAFT; PRIORITY JOURNAL; SERODIAGNOSIS; VIRION;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; DNA VIRUSES; HUMAN HERPESVIRUS 5;

EID: 0032899860     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.37.1.179-188.1999     Document Type: Article

References (33)

1. Blok, M. J., V. J. Goossens, S. J. Vanherle, B. Top, N. Tacken, J. M. Middeldorp, M. H. Christiaans, J. P. van Hooff, and C. A. Bruggeman. 1998. Diagnostic value of monitoring human cytomegalovirus late pp67 mRNA expression in renal-allograft recipients by nucleic acid sequence-based amplification. J. Clin. Microbiol. 36:1341-1346.
2. Fields, G. B., and R. L. Noble. 1990. Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. Int. J. Pept. Protein Res. 35:161-214.
3. Geysen, H. M., R. H. Meloen, and S. J. Barteling. 1984. Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid. Proc. Natl. Acad. Sci. USA 81:3998-4002.
4. Geysen, H. M., S. J. Rodda, T. J. Mason, G. Tribbick, and P. G. Schoofs. 1987. Strategies for epitope analysis using peptide synthesis. J. Immunol. Methods 102:259-274.
5. Gleaves, C. A., T. F. Smits, E. A. Shuster, and G. R. Pearson. 1985. Comparison of standard tube and shell vial culture techniques for the detection of cytomegalovirus in clinical specimens. J. Clin. Microbiol. 21:217-221.
6. Goztan, J., J. P. Laporte, S. Lesage, M. Labopin, A. Majman, N. C. Gorin, and J. C. Petit. 1946. Monitoring of cytomegalovirus infection and disease in bone marrow recipients by reverse transcription-PCR and comparison with PCR and blood and urine cultures. J. Clin. Microbiol. 34:2085-2088.
7. Hayes, K., C. Alford, and W. Britt. 1987. Antibody response to virus-encoded proteins after cytomegalovirus mononuclcosis. J. Infect. Dis. 156:615-621.
8. Ho, M. 1990. Cytomegalovirus. Plenum Medical Book Company, New York. N.Y.
9. Landini, M. P., E. Rossier, and H. Schmitz. 1988. Antibodies to human cytomegalovirus structural polypeptides during primary infection. J. Virol. Methods 22:309-317.
10. Landini, M. P., M. X. Guan, G. Jahn, W. Lindenmaier, M. Mach, A. Ripalti, A. Necker, T. Lazzarotto, and B. Plachter. 1990. Large-scale screening of human sera with cytomegalovirus recombinant antigens. J. Clin. Microbiol. 28:1375-1379.
11. Landini, M. P., A. Ripalti, K. Sra, and P. Pouletty. 1991. Human cytomegalovirus structural proteins: immune reaction against pp150 peptides. J. Clin. Microbiol. 29:1868-1872.
12. Landini, M. P. 1993. New approaches and perspectives in cytomegalovirus diagnosis. Prog. Med. Virol. 40:157-177.
13. Landini, M. P., T. Lazzarotto, G. T. Maine, A. Ripalti, and R. Flanders. 1995. Recombinant mono-and polyantigens to detect cytomegalovirus-specific immunoglobulin M in human sera by enzyme immunoassay. J. Clin. Microbiol. 33:2535-2542.
14. Meyer, H., A. T. Bankier, M. P. Landini, C. M. Brown, B. G. Barrell, B. Ruger, and M. Mach. 1988. Identification and procaryotic expression of the gene coding for the highly immunogenic 28-kilodalton structural phosphoprotein (pp28) of human cytomegalovirus. J. Virol. 62:2243-2250.
15. Meyer, H., Y. Masuho, and M. Mach. 1990. The gp58/116 complex of the human cytomegalovirus represents the aminoterminal part of the precursor molecule and contains a neutralizing epitope. J. Gen. Virol. 71:2443-2450.
16. Middeldorp, J. M., J. Jongsma, A. Ter Haar, J. Schirm, and T. H. The. 1984. Detection of immunoglobulin M and G antibodies against cytomegalovirus early and late antigens by enzyme-linked immunosorbent assay. J Clin. Microbiol. 20:763-771.
17. Middeldorp, J. M., and R. H. Meloen. 1988. Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides. J. Virol. Methods 21:147-159.
18. Mocarski, E. S., I. Pereira, and N. Michael. 1985. Precise localization of genes on large animal virus genomes: use of λgt 11 and monoclonal antibodies to map the gene for a cytomegalovirus protein family. Proc. Natl. Acad. Sci. USA 82:1266-1270.
19. Morris, R. E., and C. B. Saelinger. 1982. A simple reliable method for producing electron dense markers of uniform size for use in immunoelectron microscopy. J. Immunol. Methods 49:237-246.
20. Novak, J., P. Sova, V. Krehnak, E. Hamsikova, H. Zavadova, and J. Roubal. 1991. Mapping of serologically relevant regions of human cytomegalovirus phosphoprotein pp150 using synthetic peptides. J. Gen. Virol. 72:1409-1413.
21. Nowak, B., C. Sullivan, P. Sarnow, R. Thomas, F. Bricout, J. C. Nicolas, B. Fleckenstein, and A. J. Levine. 1984. Characterization of monoclonal antibodies and polyclonul immune sera directed against human cytomegalovirus virion proteins. Virology 132:325-338.
22. Ohlin, M., B. Plachter, V. A. Sundqvist, P. G. Steenbakkers, J. M. Middeldorp, and C. A. Borreback. 1995. Human antibody reactivity against the lower malrix protein (pp65) produced by cytomegalovirus. Clin. Diagn. Lab. Immunol. 2:325-329.
23. Plachter, B., L. Wiecdzorek, B. C. Scholl, R. Ziegelmaier, and G. Jahn. 1992. Detection of cytomegalovirus antibodies by an enzyme-linked immunosorbent assay using recombinant polypeptides of the large phosphorylated tegument protein pp150. J. Clin. Microbiol. 30:201-206.
24. Rasmussen, L., C. Matkin, R. Spaete, C. Pachl, and T. C. Merigan. 1991. Antibody response to human cytomegalovirus glycoprotein gB and gH after natural infection in humans. J. Infect. Dis. 164:835-842.
25. Revello, M. G., E. Percivalle, and G. Gerna. 1986. Immunoglobulin M to the membrane of uninfected fibroblasts in primary human cytomegalovirus infections. Microbiology 9:127-138.
26. Seven, B., M. P. Landini, and E. Govoni. 1988. Human cytomegalovirus morphogenesis: an ultrastructural study of the late cytoplasmic phases. Arch. Virol. 98:51-64.
27. Spaete, R. R., R. Gehrz, and M. P. Landini. 1994. Human cytomegalovirus structural proteins. J. Gen. Virol. 75:3287-3308.
28. Spector, S. A., R. Wong, K. Hsia, M. Pilcher, and M. J. Stempien. 1998. Plasma cytomegalovirus (CMV) DNA load predicts CMV disease and survival in AIDS patients. J. Clin. Invest. 101:497-502.
29. The, T. H., A. P. Van den Berg, M. C. Harmsen, W. Van der Beij, and W. J. Van Son. 1995. The cytomegalovirus antigenemia assay: a plea for standardisation. Scand. J. Infect. Dis. Suppl. 99:25-29.
30. Urban, M., T. Winkler, M. P. Landini, W. Britt, and M. Mach. 1994. Epitope-specific distribution of IgG subclasses against antigenic domains on glycoproteins of human cytomegalovirus. J. Infect. Dis. 169:83-90.
31. Van Loon, A. M., F. W. A. Heessen, J. T. M. Van der Loght, and J. Van der Veen. 1981. Direct enzyme-linked immunosorbent assay that uses peroxidase-labeled antigen for determination of immunoglobulin M antibody to cytomegalovirus. J. Clin. Microbiol. 13:416-422.
32. Van Zanten, J., M. Van der Giessen, W. J. Van Son, and T. H. The. 1993. Antibody responses to human cytomegalovirus-specific polypeptides studied by immunoblotting in relation to viral load during cytomegalovirus infection. J. Med. Virol. 39:80-87.
33. Vornhagen, R., B. Plachter, W. Hinderer, T. H. The, J. Van Zanten, L. Matter, C. A. Schmidt, H. H. Sonneborn, and G. Jahn. 1994. Early serodiagnosis of acute human cytomegalovirus infection by enzyme-linked immunosorbent assay using recombinant antigens. J. Clin. Microbiol. 32:981-986.