Carbocations in the synthesis of prostaglandins by the cyclooxygenase of PGH synthase? A radical departure

Protein Science

Volumn 8, Issue 5, 1999, Pages 1087-1098

  Dean, Antony M ^a   Dean, Francis M ^b,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c Pensby Hall ^*  (United Kingdom)

Author keywords

Arachidonic acid; Carbocation; Cyclization; Dioxygenase; Hydrogen 1,4 shift; Orbital symmetry; Prostaglandin G H synthase; Suicide inhibition

Indexed keywords

ARACHIDONIC ACID; HYDROGEN; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE;

ACETYLATION; ARTICLE; CHIRALITY; CONFORMATION; CYCLIZATION; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROXYLATION; OXIDATION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTON TRANSPORT; STEREOCHEMISTRY;

EID: 0032899824     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.5.1087     Document Type: Article

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