Age-related changes in [3H]strychnine binding in the vestibular nuclei of rats

Hearing Research

Volumn 127, Issue 1-2, 1999, Pages 103-107

  Nakayama, Meiho ^a,b   Caspary, Donald M ^a   Konrad, Horst R ^a   Milbrandt, Joseph C ^a   Helfert, Robert H ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Aging; Brain; Glycine receptor; Receptor autoradiography

Indexed keywords

GLYCINE RECEPTOR; STRYCHNINE;

AGING; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; VESTIBULAR NUCLEUS;

AGING; ANIMALS; AUTORADIOGRAPHY; MALE; RATS; RATS, INBRED F344; RECEPTORS, GLYCINE; STRYCHNINE; VESTIBULAR NUCLEI;

EID: 0032899705     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5955(98)00177-4     Document Type: Article

References (22)

1. Banay-Schwartz, M., Lajtha, A., Palkovits, M., 1989. Changes with aging in the levels of amino acids in rat CNS structural elements - II. Taurine and small neutral amino acids. Neurochem. Res. 14, 563-570.
2. 3H]strychnine binding sites. Brain Res. Bull. 15, 473-486.
3. Furuya, N., Yabe, T., Koizumi, T., 1992. Neurotransmitters in the vestibular commissural system of the cat. Ann. NY Acad. Sci. 22, 594-601.
4. Hunter, C., Chung, E., Van Woert, M.H., 1989. Age-dependent changes in brain glycine concentration and strychnine-induced seizures in the cat. Brain Res. 482, 247-251.
5. Krenning, J., Hughes, L.F., Caspary, D.M., Helfert, R.H., 1998. Age-related glycine receptor subunit changes in the cochlear nucleus of Fischer-344 rats. Laryngoscope 108, 26-31.
6. Lapeyre, P.N., De Waele, C., 1995. Glycinergic inhibition of spontaneously active guinea-pig medial vestibular nucleus neurons in vitro. Neurosci. Lett. 188, 155-158.
7. Lopez, I., Honrubia, V., Baloh, R.W., 1997. Aging and the human vestibular nucleus. J. Vestib. Res. 7, 77-85.
8. Markham, C.H., 1996. How does the brain generate horizontal vestibular nystagmus? In: Baloh, R.W., Halmagyi, G.M. (Eds.), Disorders of the Vestibular System. Oxford University Press, New York, pp. 48-61.
9. 3H]strychnine binding sites in the cochlear nucleus of the Fischer 344 rat. Neuroscience 67, 713-719.
10. Nakayama, M., Helfert, R.H., Konrad, H.R., Caspary, D.M., 1994. Scanning electron microscopic evaluation of age-related changes in the rat vestibular epithelium. Otolaryngol. Head Neck Surg. 111, 799-806.
11. 3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography. J. Neurosci. 3, 1189-1198.
12. 3H]strychnine. Neuroscience 17, 11-35.
13. Sato, K., Zhang, J.H., Saika, T., Sato, M., Tada, K., Tohyama, M., 1991. Localization of glycine receptor alpha 1 sub unit mRNA-containing neurons in the rat brain: an analysis using in situ hybridization histochemistry. Neuroscience 43, 381-395.
14. Sharpe, J.A., Johnston, J.L., 1993. The vestibulo-ocular reflex: clinical, anatomic, and physiologic correlates. In: Sharpe, J.A., Barber, H.O. (Eds.), The Vestibulo-Ocular Reflex and Vertigo. Raven Press, New York, pp. 15-39.
15. Shepard, N.T., Telian, S.A., 1996. Practical Management of the Balance Disorder Patient. Singular, San Diego, pp. 1-16.
16. Smith, P.F., Darlington, C.L., Hubbard, J.I., 1991. Evidence for inhibitory amino acid receptors on guinea pig medial vestibular nucleus neurons in vitro. Neurosci. Lett. 121, 244-246.
17. Spencer, R.F., Baker, R., 1992. GABA and glycine as inhibitory neurotransmitters in the vestibuloocular reflex. Ann. NY Acad. Sci. 22, 602-611.
18. Stein, M.B., Carpenter, M.B., 1967. Central projections of portions of the vestibular ganglia innervating specific parts of the labyrinth in the rhesus monkey. Am. J. Anat. 120, 281-313.
19. Tatton, W.G., Greenwood, C.E., Salo, P.T., Seniuk, N.A., 1991. Transmitter synthesis increases in substantia nigra neurons of the aged mouse. Neurosci. Lett. 131, 179-182.
20. Walberg, F., Ottersen, O.P., Rinvik, E., 1990. GABA, glycine, aspartate, glutamate and taurine in the vestibular nuclei: an immunocytochemical investigation in the cat. Exp. Brain Res. 79, 547-563.
21. Willott, J.F., Milbrandt, J.C., Bross, L.S., Caspary, D.M., 1997. Glycine immunoreactivity and receptor binding in the cochlear nucleus of C57BL/6J and CBA/CaJ mice: effects of cochlear impairment and aging. J. Comp. Neurol. 385, 405-414.
22. 3H]strychnine. J. Neurosci. 1, 532-547.