A putative role for calpain in demyelination associated with optic neuritis

Histology and Histopathology

Volumn 14, Issue 2, 1999, Pages 649-656

  Banik, N L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Calcium; Calpain; Calpastatin; Multiple sclerosis; Optic neuritis

Indexed keywords

CALPAIN; FODRIN; MYELIN ASSOCIATED GLYCOPROTEIN; NEUROFILAMENT PROTEIN;

DEMYELINATING DISEASE; HUMAN; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MACROPHAGE MIGRATION; MICROGLIA; NONHUMAN; OPTIC NERVE DISEASE; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REVIEW; T LYMPHOCYTE ACTIVATION;

ANIMALS; CALPAIN; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; OPTIC NEURITIS; RATS;

EID: 0032899495     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

1. Allen I. (1983). Hydrolytic enzymes in multiple sclerosis. In: Progress in neuropathology. Zimmerman H.M. (ed). Raven Press. New York. 5, pp1-17.
2. Banik N.L. (1992). Pathogenesis of myelin breakdown in demyelinating diseases: role of proleolytic enzymes. Crit. Rev. Neurobiol. 16, 257-271.
3. Banik N.L, Chakrabarti A.K. and Hogan E.L (1992). Calcium-Activated neutral proteinase in myelin: its role and function. In: Myelin: biology and chemistry. Martenson R. (ed). Boca Raton. CRC Press, pp 571-598.
4. Banik N.L., Chou S., Deibler G.E., Krufzch H. and Hogan E.L. (1994). Peptide bond specificity of calpain: Proteolysis of human myelin basic protein (HMBP). J. Neurosci. Res. 37, 489-496.
5. Banik N.L., Matzelle D., Gantt-Wilford G., Osborne A. and Hogan E.L. (1997). Increased calpain activity and content in spinal cord injury: Progressive degradation of 68kD and 200kD neurofilament protein in trauma. Brain Res. 752, 301-306.