Competitive NMDA receptor antagonists disrupt prepulse inhibition without reduction of startle amplitude in a dopamine receptor-independent manner in mice

European Journal of Pharmacology

Volumn 364, Issue 2-3, 1999, Pages 133-140

  Furuya, Yoshiaki ^a   Kagaya, Takaki ^a   Ogura, Hiroo ^a   Nishizawa, Yukio ^a  

^a EISAI CO LTD   (Japan)

Author keywords

CGS 19755; Haloperidol; NMDA receptor; Prepulse inhibition; R CPP; Schizophrenia

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 4 PHOSPHONOMETHYLPIPECOLIC ACID; APOMORPHINE; DIZOCILPINE; DOPAMINE RECEPTOR; HALOPERIDOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENCYCLIDINE;

ARTICLE; DRUG EFFECT; PREPULSE INHIBITION; PRIORITY JOURNAL; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; STARTLE REFLEX;

ANALYSIS OF VARIANCE; ANIMALS; APOMORPHINE; BINDING, COMPETITIVE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; HALOPERIDOL; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SUBCUTANEOUS; MALE; MICE; PIPECOLIC ACIDS; PIPERAZINES; RECEPTORS, DOPAMINE; RECEPTORS, N-METHYL-D-ASPARTATE; STARTLE REACTION;

EID: 0032898889     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00839-5     Document Type: Article

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