Detection methods of possible prion contaminants in collagen and gelatin

Archives of Virology

Volumn 144, Issue 1, 1999, Pages 177-184

  Nemoto, T ^a   Horiuchi, M ^a   Ishiguro, N ^a   Shinagawa, M ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ENZYME DEGRADATION; GELATIN; MACROGOL; MICROORGANISM DETECTION; PRION; PROTEINASE; SODIUM CHLORIDE; VISCOSITY; WESTERN BLOTTING;

RODENTIA; SCRAPIE PRION;

EID: 0032898133     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007050050494     Document Type: Article

References (16)

1. 1. Andrew FH (1997) Type of prion protein in UK farmers with Creutzfeldt-Jakob disease. Lancet 350: 188
2. 2. Golker CF, Whiteman MD, Gugel KH, Gilles R, Stadler P, Kovatch RM, Lister D, Wisher MH, Calcagni C, Hubner (1996) Reduction of the infectively of scrapie agent as a model for BSE in the manufacturing process of trasylol. Biologicals 24: 103-111
3. Sc. Arch Virol 141: 1863-1874
4. C) exists in many non-neuronal tissues of sheep. J Gen Virol 76: 2 583-2 587
5. 5. Hubner GE, Koch R-C, Sprenger KBG, Stadler, WPJ, Golker CF (1996) Examination of the Biological Safety of a Drug Derived from Mammalian Organs. Arzneimittelforschung 46: 657-661
6. 6. Ikegami Y, Ito M, Isomura H, Momotani E, Sasaki K, Muramatsu Y, Ishiguro N, Shinagawa M (1991) Pre-clinical and clinical diagnosis of scrapie by detection of PrP protein in tissues of sheep. Vet Rec 128: 271-275
7. 7. Kirkwood JK, Wells GAH, Wilesmith JW, Cunningham AA, Jackson SI (1990) Spongiform encephalopathy in an Arabian Oryx (Oryx leucoryx) and a Greater Kudu (Trangelaphus strepsiceros). Vet Rec 127: 418
8. 8. Kirkwood JK, Cunningham AA, Wells GAH, Wileshmith JW, Barnett JEF (1993) Spongiform encephalopathy in a herd of Greater Kudu (Trangelaphus strepsiceros): epidemiological observations. Vet Rec 133: 360-364
9. Sc in sheep at the preclinical stage of scrapie and its significance for diagnosis of insidious infection. Arch Virol 134: 427-432
10. 10. Prusiner SB (1991) Molecular biology of prion diseases. Science 252: 1 515-1 521
11. 11. Prusiner SB (1994) Molecular biology and genetics of prion diseases. Phil Trans R Soc London 343: 447-463
12. 12. Wells GAH, Scott AC, Jackson, CT, Gunning RF, Hancock RD, Jeffrey M, Dawson M, Bredley R (1987) A novel progressive spongiform encephalopathy in cattle. Vet Rec 121: 419-420
13. 13. Wilesmith JW, Kelly DF, Ryan JBM, Atkinson MJ (1991) Bovine spongiform encephalopathy: epidemiological studies on the origin. Vet Rec 128: 199-203
14. 14. Will RG, Ironside JW, Zeidler M, Cousens SN, Estiberio K, Alperovitch A, Poser S, Pocchiari M, Hofman A, Smith PG (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347: 921-925
15. 15. Willoughby K, Kelly DF, Lyon DG, Wells GAH (1992) Spongiform encephalopathy in a captive puma (Felis concolor). Vet Rec 131: 431 -434
16. 16. Wyatt JM, Pearson GR, Smerdon TN, Gruffydd-Jones TJ, Wells GAH, Wilesmith, JW (1991) Naturally occurring scrapie-like spongiform encephalopathy in five domestic cats. Vet Rec 129: 233-236