Wasting in cancer

Journal of Nutrition

Volumn 129, Issue 1 SUPPL., 1999, Pages

  Tisdale, Michael J ^a  

^a ASTON UNIVERSITY   (United Kingdom)

Author keywords

Cachexia; Cancer; Wasting

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOKINE; GAMMA INTERFERON; ICOSAPENTAENOIC ACID; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; LIPOPROTEIN LIPASE; POLYUNSATURATED FATTY ACID; PROTEASOME; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN;

ANOREXIA; BODY COMPOSITION; CACHEXIA; CANCER PATIENT; CLINICAL TRIAL; CONFERENCE PAPER; ENERGY EXPENDITURE; FOOD INTAKE; HUMAN; LIPID METABOLISM; NONHUMAN; PROTEIN DEGRADATION; QUALITY OF LIFE; SURVIVAL TIME; WASTING SYNDROME; WEIGHT REDUCTION;

EID: 0032897962     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/129.1.243s     Document Type: Conference Paper

References (47)

1. Beck, S. A., Groundwater, P., Barton, C. & Tisdale, M. J. (1990) Alterations in serum lipolytic activity of cancer patients with response to therapy. Br. J. Cancer 62: 822-825.
2. Beck, S. A. & Tisdale, M. J. (1987) Production of lipolytic and proteolytic factors by a murine tumor-producing cachexia in the host. Cancer Res. 47: 5919-5923.
3. Costa, G., Bewley, P., Aragon, M. & Siebold, J. (1981) Anorexia and weight loss in cancer patients. Cancer Treat. Rep. 65(Suppl. 5): 3-7.
4. Costelli, P., Carbo, N., Tessitore, L., Bagby, C. J., Lopez-Soriano, F. J., Argiles, J. M. & Baccino, F. M. (1993) Tumor necrosis factor-α mediates changes in tissue protein turnover in a rat cachexia model. J. Clin. Invest. 92: 2783-2789.
5. DeWys, W. D. (1972) Anorexia as a general effect of cancer. Cancer 45: 2013-2019.
6. DeWys, W. D., Begg, C., Lavin, P. T., Bennett, J. M., Bertino, J. R., Cohen, M. H., Douglass Jr., H. D., Engstrom, P. F., Ezdinlie, Z., Horton, J., Johnson, G. J., Moertel, C. G., Oken, M. M., Perla, C., Rosenbaum, C., Sinerstein, M. N., Skeel, R. T., Sponzo, R. W. & Tormey, D. C. (1980) Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am. J. Med. 69: 491-496.
7. Drott, C., Persson, H. & Lundholm, K. (1989) Cardiovascular and metabolic response to adrenaline infusion in weight-losing patients with and without cancer. Clin. Physiol. 9: 427-439.
8. Ebisui, C., Tsujinaka, T., Morimoto, T., Kan, K., Iijima, S., Yano, M., Kominami, E., Tanaka, K. & Monden, M. (1995) Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes. Clin. Sci. 89: 431-439.
9. Evans, W. K., Makuch, R., Clamon, G. H., Feld, R., Weiner, R. S., Moran, E., Blum, R., Shepherd, F. A., Jeejeebhoy, N. K. & DeWys, W. D. (1985) Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung carcinoma. Cancer Res. 45: 3347-3353.
10. Falconer, J. S., Fearon, K. C., Plester, C. E., Ross, J. A. & Carter, D. C. (1994) Cytokines, the acute-phase response, and resting energy expenditure in cachectic patients with pancreatic cancer. Ann. Surg. 219: 325-331.
11. Fearon, K.C.H., Hansell, D. T., Preston, T., Plumb, J. A., Davies, J., Shapiro, D., Shenkin, A., Calman, K. C. & Burns, H.J.C. (1988) Influence of whole body protein turnover rate on resting energy expenditure in patients with cancer. Cancer Res. 48: 2590-2595.
12. Fredix, E. W., Saris, W. H., Soeters, P. B., Wouters, E. F., Kester, A. D., von Meyenfeldt, M. F. & Westerterp, K. R. (1990) Estimation of body composition by bioelectrical impedance in cancer patients. Eur. J. Clin. Nutr. 44: 749-752.
13. Fredrix, E.W.H.M., Soeters, P. B., Wouters, E.F.M., Deerenberg, I. M., Von-Meyerfeldt, M. F. & Saris, W.H.M. (1991) Effect of different tumor types on resting energy expenditure. Cancer Res. 51: 6138-6141.
14. 2 production in rat skeletal muscle in fever is signaled by a macrophage product distinct from interleukin-1 or other known monokines. J. Clin. Invest. 81: 1378-1383.
15. Groundwater, P., Beck, S. A., Barton, C., Adamson, C., Ferrier, I. N. & Tisdale, M. J. (1990) Alteration of serum and urinary lipolytic activity with weight loss in cachectic cancer patients. Br. J. Cancer 62: 816-821.
16. Grosvenor, M., Bulcavage, L. & Chlebowski, R. T. (1989) Symptoms potentially influencing weight loss in a cancer population. Cancer 63: 330-335.
17. Grunfeld, C., Kotler, D. P., Hamadch, R., Tierney, A., Wang, J. & Pierson, R. N. (1989) Hypertriglyceridemia in the acquired immunodeficiency syndrome. Am. J. Med. 86: 27-31.
18. Grunfeld, C. & Feingold, K. R. (1991) Tumor necrosis factor, cytokines and hyperlipidemia of infection. Trends Endocrinol. Metabol. 2: 213-219.
19. Hauner, H., Petruschke, T., Russ, M., Röhrig, K. & Eckel, J. (1995) Effects of tumour necrosis factor alpha (TNFα) on glucose transport and lipid metabolism of newly-differentiated human fat cells in culture. Diabetologica 38: 764-771.
20. Heber, D., Chlebowski, R. T., Ishibashi, D. E., Herrold, J. N. & Block, J. B. (1982) Abnormalities in glucose and protein metabolism in non-cachectic lung cancer patients. Cancer Res. 42: 4815-4819.
21. Kardinal, C. G., Loprinzi, C. L., Schaid, D. J., Hass, A. C., Dose, A. M., Athmann, L. M., Mailliard, J. A., McCormack, G. W., Gerstair, J. B. & Schray, M. F. (1990) A controlled trial of cyproheptadine in cancer patients with anorexia and/or cachexia. Cancer 65: 2657-2662.
22. Kitada, S., Hays, E. F. & Mead, J. F. (1980) A lipid mobilizing factor in serum of tumor-bearing mice. Lipids 15: 168-174.
23. Knox, C. S., Crosby, C. O., Fuerer, I. D., Buzby, G. P., Clifford, M. D. & Müllen, J. L. (1983) Energy expenditure in malnourished cancer patients. Ann. Surg. 197: 152-162.
24. Llovera, M., Garcia-Martinez, C., Agell, N., Lopez-Soriano, F. J. & Argilés, J. M. (1997) TNF can directly induce the expression of ubiquitin-dependent proteolytic system in rat soleus muscle. Biochim. Biophys. Res. Commun. 230: 238-241.
25. Llovera, M., Garcia-Martinez, C., Agell, N., Marzabal, M., Lopez-Soriano, F. J. & Argiles, J. M. (1994) Ubiquitin gene-expression is increased in skeletal muscle of tumour-bearing rats. FEBS Lett. 338: 311-318.
26. Llovera, M., Lopez-Soriano, F. J. & Argilés, J. M. (1993) Effects of tumor necrosis factor-α on muscle protein turnover in female Wistar rats. J. Natl. Cancer Inst. 85: 1334-1339.
27. Loprinzi, C. L., Michalak, J. C., Schaid, D. J., Maillard, J. A., Athmann, L. M., Goldberg, R. M., Tschetler, L. K., Hatfield, A. K. & Morion, R. F. (1993a) Phase III evaluation of four doses of megestrol acetate as therapy for patients with anorexia and/or cachexia. J. Clin. Oncol. 11: 762-767.
28. Loprinzi, C. L., Schaid, D. J., Dose, A. M., Burnham, N. L. & Jensen, M. D. (1993b) Body composition changes in patients who gain weight while receiving megestrol acetate. J. Clin. Oncol. 11: 152-157.
29. Lundholm, K., Bylund, A. C., Holm, J. & Schersten, T. (1976) Skeletal muscle metabolism in patients with malignant tumor. Eur. J. Cancer 12: 465-473.
30. Marshall, M. K., Doerrler, W., Feingold, K. R. & Grunfeld, C. (1994) Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes. Endocrinology 135: 141-147.
31. Masuno, H., Yamasaki, N. & Okuda, H. (1981) Purification and characterization of a lipolytic factor (Toxohormone-L) from cell-free fluid of ascites Sarcoma 180. Cancer Res. 41: 284-288.
32. McMillan, D. C., Preston, T., Watson, W. S., Simpson, J. M., Fearon, K. C. H., Shenkin, A., Burns, H.J.G. & McArdle, C. S. (1994) Relationship between weight loss, reduction of body cell mass and inflammatory response in patients with cancer. Br. J. Surg. 81: 1011-1014.
33. Morrison, S. D. (1976) Control of food intake in cancer cachexia: a challenge and a tool. Physiol. Behav. 17: 705-714.
34. Nixon, D. W., Heymsfield, S. B., Cohen, A. E., Kutner, M. H., Ansley, J., Lawson, D. H. & Rudman, D. (1980) Protein-calorie undernutrition in hospitalised cancer patients. Am. J. Med. 68: 683-690.
35. Nixon, D. W., Kutner, M., Heymsfield, S., Foltz, A. T., Carty, C., Seitz, S., Casper, K., Evans, W. K., Jeejeebhoy, K. N., Daly, J. M., Heber, D., Poppendiek, H. & Hoffman, F. A. (1988) Resting energy expenditure in lung and colon cancer. Metabolism 37: 1059-1064.
36. Oversen, L., Allingstrup, L., Hannibal, J., Mortensen, E. L. & Hanson, O. P. (1993) Effect of dietary counseling on food intake, body weight, response rate, survival and quality of life in cancer patients undergoing chemotherapy. A prospective, randomized study. J. Clin. Oncol. 11: 2043-2048.
37. Palomares, M. R., Sayre, J. W., Shekar, K. C., Lillington, L. M. & Chlewoski, R. T. (1996) Gender influence on weight-loss pattern and survival of non-small cell lung carcinoma patients. Cancer 78: 2119-2126.
38. Rofe, A. M., Bourgeois, C. S., Coyle, P., Taylor, A. & Abdi, E. A. (1994) Altered insulin response to glucose in weight-losing cancer patients. Anticancer Res. 14: 647-650.
39. Shaw, J. H. & Wolfe, R. R. (1987) Fatty acid and glycerol kinetics in septic patients and in patients with gastrointestinal cancer. Ann. Surg. 205: 368-375.
40. Smith, K. L. & Tisdale, M. J. (1993) Mechanism of muscle protein degradation in cancer cachexia. Br. J. Cancer 68: 314-318.
41. Strassman, G. & Kambayashi, T. (1995) Inhibition of experimental cancer cachexia by anti-cytokine and anti-cytokine receptor therapy. Cytokines Mol. Ther. 1: 107-113.
42. Thompson, M. P., Cooper, S. T., Parry, B. R. & Tuckey, J. A. (1993) Increased expression of the mRNA for hormone-sensitive lipase in adipose tissue of cancer patients. Biochim. Biophys. Acta 1180: 236-242.
43. Tisdale, M. J. & Beck, S. A. (1991) Inhibition of tumour-induced lipolysis in vitro and cachexia and tumour growth in vivo by eicosapentaenoic acid. Biochem. Pharmacol. 41: 103-107.
44. Todorov, P., Cariuk, P., McDevitt, T., Coles, B., Fearon, K. & Tisdale, M. (1996a) Characterization of a cancer cachectic factor. Nature 379: 739-742.
45. Todorov, P. T., McDevitt, T. M., Cariuk, P., Coles, B., Deacon, M. & Tisdale, M. J. (1996b) Induction of muscle protein degradation and weight loss by a tumor product. Cancer Res. 56: 1256-1261.
46. Wigmore, S. J., Plester, C. E., Richardson, R. A. & Fearon, K. C. H. (1997) Changes in nutritional status associated with unresectable pancreatic cancer. Br. J. Cancer 75: 106-109.
47. Wigmore, S. J., Ross, J. A., Falconer, J. S., Plester, C. E., Tisdale, M. J., Carter, D. C. & Fearon, K. C. H. (1996) The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer. Nutrition 12(Suppl.): S27-S30.