Significant enhancement of lipase enantioselectivity toward (S)-Ketoprofen ester at pH 2

Biotechnology Letters

Volumn 21, Issue 2, 1999, Pages 143-146

  Liu, You Yan ^a   Xu, Jian He ^a   Xu, Qiu Ge ^a   Hu, Ying ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

(S) Ketoprofen; Activity; Candida rugosa lipase; Enantioselectivity; pH effect

Indexed keywords

ESTER; KETOPROFEN; KETOPROFEN DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ARTICLE; CANDIDA RUGOSA; CONTROLLED STUDY; ENANTIOMER; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STABILITY; HYDROLYSIS; NONHUMAN; PH; STEREOCHEMISTRY;

CANDIDA RUGOSA;

EID: 0032897737     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005413100578     Document Type: Article

References (12)

1. Chen CS, Fujimoto Y, Girdaukas G, Sih CJ (1982) J. Am. Chem. Soc. 104: 7294-7299.
2. Chen P-Y, Wu S-H, Wang, K-T (1993) Biotechnol. Lett. 15: 181-184.
3. Cobbs CS, Barton MJ, Peng L, Goswami A, Malick AP, Hamman JP, Calton GJ (1992) US Patent 5: 108-916.
4. Famaey JP, Paulus, HE (1992) Therapeutic Applications of NSAIDs. New York: Marcel Dekker.
5. Hernaiz MJ, Sanchez-Montero JM, Sinisterra JV (1995) J. Mol. Catal. 96: 317-327.
6. Lam KP, Hui AHF, Jones JB (1986) J. Org. Chem. 51: 2047-2050.
7. Linfield WM, Barauskas RA, Sivieri L, Serota S, Stevesones RW (1984) J. Am. Oil. Chem. Soc. 61: 191-195.
8. Pronk W, Boswinkel G, Riet K (1992) Enzyme Microb. Technol. 14: 214-220.
9. Schneider M, Engel N, Honicke P, Heinemann G, Gorisch H (1984) Angew. Chem. Int. Ed. Engl. 23: 67-68.
10. Sohn HS, Chung SS, Rhee JS (1987) Biotechnol. Lett. 6: 623-633.
11. Wang YJ, Sheu JY, Wang FF, Shaw JF (1988) Biotechnol. Bioeng. 31: 628-633.
12. Wu SH, Guo Z-W, Sih C-J (1990) J. Am. Chem. Soc. 112: 1990-1995.