-
1
-
-
33745464490
-
Fluorinated pyrimidine: A new class of tumor-inhibitory compounds
-
Heidelberger C, Duschinsky R: Fluorinated pyrimidine: a new class of tumor-inhibitory compounds. Nature 179: 663-666, 1957.
-
(1957)
Nature
, vol.179
, pp. 663-666
-
-
Heidelberger, C.1
Duschinsky, R.2
-
2
-
-
0021689688
-
Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity
-
Leyva A, Van Groeningen CJ, Kraal I, Gall H, Peters GJ, Lankelma J, and Pinedo HM: Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity. Cancer Res 44: 5928-5933, 1984.
-
(1984)
Cancer Res
, vol.44
, pp. 5928-5933
-
-
Leyva, A.1
Van Groeningen, C.J.2
Kraal, I.3
Gall, H.4
Peters, G.J.5
Lankelma, J.6
Pinedo, H.M.7
-
3
-
-
0022624346
-
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid
-
Machover D, Goldschmidt E, Chollet P, Metzger G, Zittoun J, Marquet J, Vandenbulcke J-M, Misset J-L, Schwarzenberg L, Fourtillan JB, Gaget H and Mathe G: Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. J Clin Oncol 4: 685-696, 1986.
-
(1986)
J Clin Oncol
, vol.4
, pp. 685-696
-
-
Machover, D.1
Goldschmidt, E.2
Chollet, P.3
Metzger, G.4
Zittoun, J.5
Marquet, J.6
Vandenbulcke, J.-M.7
Misset, J.-L.8
Schwarzenberg, L.9
Fourtillan, J.B.10
Gaget, H.11
Mathe, G.12
-
4
-
-
0018216763
-
Effects of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil
-
Fujii S, Ikenaka K, Fukushima M and Shirasaka T: Effects of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil. Gann 69: 763-772, 1978.
-
(1978)
Gann
, vol.69
, pp. 763-772
-
-
Fujii, S.1
Ikenaka, K.2
Fukushima, M.3
Shirasaka, T.4
-
5
-
-
0025604967
-
Phase II trial of UFT in advanced colorectal and gastric cancer
-
Malik STA, Talbot D, Clarke PI, Osborne R, Reznek R, Wringley PFM and Slevin ML: Phase II trial of UFT in advanced colorectal and gastric cancer. Br J Cancer 62: 1023-1025, 1990.
-
(1990)
Br J Cancer
, vol.62
, pp. 1023-1025
-
-
Malik, S.T.A.1
Talbot, D.2
Clarke, P.I.3
Osborne, R.4
Reznek, R.5
Wringley, P.F.M.6
Slevin, M.L.7
-
6
-
-
0024510302
-
5-Fluorouracil and UFT-sensitive gastric carcinoma has a high level of thymidylate synthetase
-
Maehara Y, Kusumoto T, Kusumoto H, Anai H, Sakaguchi Y, Kido Y, Okamura T, Korenaga D and Sugimachi K: 5-Fluorouracil and UFT-sensitive gastric carcinoma has a high level of thymidylate synthetase. Cancer 63: 1593-1696, 1989.
-
(1989)
Cancer
, vol.63
, pp. 1593-1696
-
-
Maehara, Y.1
Kusumoto, T.2
Kusumoto, H.3
Anai, H.4
Sakaguchi, Y.5
Kido, Y.6
Okamura, T.7
Korenaga, D.8
Sugimachi, K.9
-
7
-
-
0021223573
-
Cytochrome P-450-dependent oxidative cleavage of 1-(tetrahydro-2-furanyl)-5-fluorouracil to 5-fluorouracil
-
Kawata S, Minami S, Tarui S, Marunaka T, Okamoto M and Yamano T: Cytochrome P-450-dependent oxidative cleavage of 1-(tetrahydro-2-furanyl)-5-fluorouracil to 5-fluorouracil. Jpn J Pharmacol 36: 43-49, 1984.
-
(1984)
Jpn J Pharmacol
, vol.36
, pp. 43-49
-
-
Kawata, S.1
Minami, S.2
Tarui, S.3
Marunaka, T.4
Okamoto, M.5
Yamano, T.6
-
8
-
-
0026597828
-
Intracellular metabolism of 5-formyl tetrahydrofolate in human breast and colon cell lines
-
Boarman DM and Allegra CJ: Intracellular metabolism of 5-formyl tetrahydrofolate in human breast and colon cell lines. CancerRes 52: 36-44, 1992.
-
(1992)
CancerRes
, vol.52
, pp. 36-44
-
-
Boarman, D.M.1
Allegra, C.J.2
-
9
-
-
0014439796
-
Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas
-
Sneider TW, Potter VR and Morris HP: Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas. Cancer Res 29: 40-54, 1969.
-
(1969)
Cancer Res
, vol.29
, pp. 40-54
-
-
Sneider, T.W.1
Potter, V.R.2
Morris, H.P.3
-
10
-
-
0018124123
-
Human colon tumors: Enzymic and histological characteristics
-
Herzfeld A, Legg MA and Greengard O: Human colon tumors: Enzymic and histological characteristics. Cancer 42: 1280-1283, 1978.
-
(1978)
Cancer
, vol.42
, pp. 1280-1283
-
-
Herzfeld, A.1
Legg, M.A.2
Greengard, O.3
-
12
-
-
0019271884
-
High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometricdetermination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur
-
Marunaka T, Umeno Y, Yoshida K, Nagamachi M, Minami Y and Fujii S: High-pressure liquid Chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometricdetermination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur. J Pharmaceutical Sci 69: 209-213, 1980.
-
(1980)
J Pharmaceutical Sci
, vol.69
, pp. 209-213
-
-
Marunaka, T.1
Umeno, Y.2
Yoshida, K.3
Nagamachi, M.4
Minami, Y.5
Fujii, S.6
-
13
-
-
84909747313
-
Histological grading of colorectal carcinoma
-
Curran RC. ed. Oxford University Press
-
Morson BC: Histological grading of colorectal carcinoma. In: Color atlas of gastrointestinal pathology (Curran RC. ed). Oxford University Press: 1988, pp 245-248.
-
(1988)
Color Atlas of Gastrointestinal Pathology
, pp. 245-248
-
-
Morson, B.C.1
-
14
-
-
0029915123
-
Multiple drug resistance-related messenger RNA expression in archival formalin-fixed paraffin-embedded human breast tumour tissue
-
O'Driscoll L, Kennedy S, McDermott E, Keleham P and Clynes M: Multiple drug resistance-related messenger RNA expression in archival formalin-fixed paraffin-embedded human breast tumour tissue. Eur JCancer 324: 128-133, 1996.
-
(1996)
Eur JCancer
, vol.324
, pp. 128-133
-
-
O'Driscoll, L.1
Kennedy, S.2
McDermott, E.3
Keleham, P.4
Clynes, M.5
-
15
-
-
0031747838
-
Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors
-
Sakamoto S, Hara Y, Mitamura T, Sassa S, Kudo H, Suzuki S, Kuwa K, Okayasu I and Shinoda H: Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors. Anti-Cancer Drugs 9: 351-357, 1998.
-
(1998)
Anti-cancer Drugs
, vol.9
, pp. 351-357
-
-
Sakamoto, S.1
Hara, Y.2
Mitamura, T.3
Sassa, S.4
Kudo, H.5
Suzuki, S.6
Kuwa, K.7
Okayasu, I.8
Shinoda, H.9
-
16
-
-
0023182429
-
Relative activities of thyminidylate synthetase and thymidine kinase in 1,2-dimethylhydrazine-induced colon carcinomas in rats
-
Sakamoto S, Kuwa K, Tsukada K, Sagara T, Kasahara N and Okamoto R: Relative activities of thyminidylate synthetase and thymidine kinase in 1,2-dimethylhydrazine-induced colon carcinomas in rats. Carcinogenesis 8: 405-408, 1987.
-
(1987)
Carcinogenesis
, vol.8
, pp. 405-408
-
-
Sakamoto, S.1
Kuwa, K.2
Tsukada, K.3
Sagara, T.4
Kasahara, N.5
Okamoto, R.6
-
17
-
-
0015210983
-
Thymidylate synthetase from amethopterin-resistant Lactobacillus casei
-
Dunlap RB, Harding NGL and Huennekens FM: Thymidylate synthetase from amethopterin-resistant Lactobacillus casei. Biochemistry 10: 88-97, 1971.
-
(1971)
Biochemistry
, vol.10
, pp. 88-97
-
-
Dunlap, R.B.1
Harding, N.G.L.2
Huennekens, F.M.3
-
18
-
-
0015522670
-
Properties of thymidine kinase partially purified from human fetal and adult tissues
-
Taylor AT, Stafford MA and Jones OW: Properties of thymidine kinase partially purified from human fetal and adult tissues. J Biol Chem 247: 1930-1935, 1972.
-
(1972)
J Biol Chem
, vol.247
, pp. 1930-1935
-
-
Taylor, A.T.1
Stafford, M.A.2
Jones, O.W.3
-
19
-
-
0023753618
-
Mechanism of innate resistance to thymidylate synthase inhibition after 5-fluorouracil
-
Spears CP, Gustavsson BG, Berne M, Frosing R, Bernstein L and Hays AA: Mechanism of innate resistance to thymidylate synthase inhibition after 5-fluorouracil. Cancer Res 48: 5894-5900, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 5894-5900
-
-
Spears, C.P.1
Gustavsson, B.G.2
Berne, M.3
Frosing, R.4
Bernstein, L.5
Hays, A.A.6
-
20
-
-
0022400840
-
Enzymes of uracil catabolism in normal and neoplastic human tissues
-
Naguib FNM, El Kouni AM and ChaS: Enzymes of uracil catabolism in normal and neoplastic human tissues. CancerRes 45: 5405-5412, 1985.
-
(1985)
CancerRes
, vol.45
, pp. 5405-5412
-
-
Naguib, F.N.M.1
El Kouni, A.M.2
Cha, S.3
-
21
-
-
0028982820
-
Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity
-
Etienne MC, Cheradame S, Fischel JL, Formento P, Dassonville O, Renee N, Schneider M, Thyss A, Demard F and Milano G: Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity. J Clin Oncol 13: 1663-1670, 1995.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1663-1670
-
-
Etienne, M.C.1
Cheradame, S.2
Fischel, J.L.3
Formento, P.4
Dassonville, O.5
Renee, N.6
Schneider, M.7
Thyss, A.8
Demard, F.9
Milano, G.10
-
22
-
-
0029095796
-
Quantitation of intratumoral thymidylate synthase expression predicts forresistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
-
Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, Stain S, Beart R and Danenberg P: Quantitation of intratumoral thymidylate synthase expression predicts forresistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial. Eur J Cancer 31: 1306-1310, 1995.
-
(1995)
Eur J Cancer
, vol.31
, pp. 1306-1310
-
-
Leichman, L.1
Lenz, H.J.2
Leichman, C.G.3
Groshen, S.4
Danenberg, K.5
Baranda, J.6
Spears, C.P.7
Boswell, W.8
Silberman, H.9
Ortega, A.10
Stain, S.11
Beart, R.12
Danenberg, P.13
-
23
-
-
0027313526
-
Pathological features and pyrimidine nucleotide synthesis in human gastric carcinomas
-
Sakamoto S, Kawachi Y, Konishi T. Pathological features and pyrimidine nucleotide synthesis in human gastric carcinomas. Anticancer Res 13: 879-882, 1993.
-
(1993)
Anticancer Res
, vol.13
, pp. 879-882
-
-
Sakamoto, S.1
Kawachi, Y.2
Konishi, T.3
-
24
-
-
0018274585
-
Pathological of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine
-
Sunter JP, Appleton DR, Wright NA and Watson AJ: Pathological of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine. Virchows Arch B Cell Pathol 29: 211-223, 1978.
-
(1978)
Virchows Arch B Cell Pathol
, vol.29
, pp. 211-223
-
-
Sunter, J.P.1
Appleton, D.R.2
Wright, N.A.3
Watson, A.J.4
-
25
-
-
0028329522
-
Gene dosage and expression, and enzyme activity of thymidine kinase and thymidylate synthase in xenografted colorectal adenocarcinomas
-
Lasserre C, Sabatier L, Beaumatin J, Luccioni C, Lefrancois D, Muleris M and Dutrillaux B: Gene dosage and expression, and enzyme activity of thymidine kinase and thymidylate synthase in xenografted colorectal adenocarcinomas. Int J Cancer 56: 506-511, 1994.
-
(1994)
Int J Cancer
, vol.56
, pp. 506-511
-
-
Lasserre, C.1
Sabatier, L.2
Beaumatin, J.3
Luccioni, C.4
Lefrancois, D.5
Muleris, M.6
Dutrillaux, B.7
-
26
-
-
0029149035
-
The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate poolin human colorectal carcinoma tissues: Changes after tegafur and uracil treatment
-
Omura K, Kawakami K, Kanehira E, Nagasato A, Kawashima S, Tawaraya K, Watanabe S, Hirano K, Shirasaka T and Watanabe Y: The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate poolin human colorectal carcinoma tissues: Changes after tegafur and uracil treatment. Cancer Res 55: 3897-3901, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 3897-3901
-
-
Omura, K.1
Kawakami, K.2
Kanehira, E.3
Nagasato, A.4
Kawashima, S.5
Tawaraya, K.6
Watanabe, S.7
Hirano, K.8
Shirasaka, T.9
Watanabe, Y.10
|