메뉴 건너뛰기




Volumn 19, Issue 1 A, 1999, Pages 245-250

Effects of 5-fluorouracil derivative UFT on thymidylate synthetase and thymidine kinase in rat colorectal tumors

Author keywords

5 fluorouracil; Histological differentiation; Rat colorectal tumors; Thymidine kinase; Thymidylate synthetase

Indexed keywords

1,2 DIMETHYLHYDRAZINE; FLUOROURACIL; PYRIMIDINE ANTAGONIST; THYMIDINE KINASE; THYMIDYLATE SYNTHASE;

EID: 0032897374     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (26)
  • 1
    • 33745464490 scopus 로고
    • Fluorinated pyrimidine: A new class of tumor-inhibitory compounds
    • Heidelberger C, Duschinsky R: Fluorinated pyrimidine: a new class of tumor-inhibitory compounds. Nature 179: 663-666, 1957.
    • (1957) Nature , vol.179 , pp. 663-666
    • Heidelberger, C.1    Duschinsky, R.2
  • 2
    • 0021689688 scopus 로고
    • Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity
    • Leyva A, Van Groeningen CJ, Kraal I, Gall H, Peters GJ, Lankelma J, and Pinedo HM: Phase I and pharmacokinetic studies of high-dose uridine intended for rescue from 5-fluorouracil toxicity. Cancer Res 44: 5928-5933, 1984.
    • (1984) Cancer Res , vol.44 , pp. 5928-5933
    • Leyva, A.1    Van Groeningen, C.J.2    Kraal, I.3    Gall, H.4    Peters, G.J.5    Lankelma, J.6    Pinedo, H.M.7
  • 4
    • 0018216763 scopus 로고
    • Effects of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil
    • Fujii S, Ikenaka K, Fukushima M and Shirasaka T: Effects of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil. Gann 69: 763-772, 1978.
    • (1978) Gann , vol.69 , pp. 763-772
    • Fujii, S.1    Ikenaka, K.2    Fukushima, M.3    Shirasaka, T.4
  • 7
    • 0021223573 scopus 로고
    • Cytochrome P-450-dependent oxidative cleavage of 1-(tetrahydro-2-furanyl)-5-fluorouracil to 5-fluorouracil
    • Kawata S, Minami S, Tarui S, Marunaka T, Okamoto M and Yamano T: Cytochrome P-450-dependent oxidative cleavage of 1-(tetrahydro-2-furanyl)-5-fluorouracil to 5-fluorouracil. Jpn J Pharmacol 36: 43-49, 1984.
    • (1984) Jpn J Pharmacol , vol.36 , pp. 43-49
    • Kawata, S.1    Minami, S.2    Tarui, S.3    Marunaka, T.4    Okamoto, M.5    Yamano, T.6
  • 8
    • 0026597828 scopus 로고
    • Intracellular metabolism of 5-formyl tetrahydrofolate in human breast and colon cell lines
    • Boarman DM and Allegra CJ: Intracellular metabolism of 5-formyl tetrahydrofolate in human breast and colon cell lines. CancerRes 52: 36-44, 1992.
    • (1992) CancerRes , vol.52 , pp. 36-44
    • Boarman, D.M.1    Allegra, C.J.2
  • 9
    • 0014439796 scopus 로고
    • Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas
    • Sneider TW, Potter VR and Morris HP: Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas. Cancer Res 29: 40-54, 1969.
    • (1969) Cancer Res , vol.29 , pp. 40-54
    • Sneider, T.W.1    Potter, V.R.2    Morris, H.P.3
  • 10
    • 0018124123 scopus 로고
    • Human colon tumors: Enzymic and histological characteristics
    • Herzfeld A, Legg MA and Greengard O: Human colon tumors: Enzymic and histological characteristics. Cancer 42: 1280-1283, 1978.
    • (1978) Cancer , vol.42 , pp. 1280-1283
    • Herzfeld, A.1    Legg, M.A.2    Greengard, O.3
  • 12
    • 0019271884 scopus 로고
    • High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometricdetermination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur
    • Marunaka T, Umeno Y, Yoshida K, Nagamachi M, Minami Y and Fujii S: High-pressure liquid Chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometricdetermination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur. J Pharmaceutical Sci 69: 209-213, 1980.
    • (1980) J Pharmaceutical Sci , vol.69 , pp. 209-213
    • Marunaka, T.1    Umeno, Y.2    Yoshida, K.3    Nagamachi, M.4    Minami, Y.5    Fujii, S.6
  • 13
    • 84909747313 scopus 로고
    • Histological grading of colorectal carcinoma
    • Curran RC. ed. Oxford University Press
    • Morson BC: Histological grading of colorectal carcinoma. In: Color atlas of gastrointestinal pathology (Curran RC. ed). Oxford University Press: 1988, pp 245-248.
    • (1988) Color Atlas of Gastrointestinal Pathology , pp. 245-248
    • Morson, B.C.1
  • 14
    • 0029915123 scopus 로고    scopus 로고
    • Multiple drug resistance-related messenger RNA expression in archival formalin-fixed paraffin-embedded human breast tumour tissue
    • O'Driscoll L, Kennedy S, McDermott E, Keleham P and Clynes M: Multiple drug resistance-related messenger RNA expression in archival formalin-fixed paraffin-embedded human breast tumour tissue. Eur JCancer 324: 128-133, 1996.
    • (1996) Eur JCancer , vol.324 , pp. 128-133
    • O'Driscoll, L.1    Kennedy, S.2    McDermott, E.3    Keleham, P.4    Clynes, M.5
  • 15
    • 0031747838 scopus 로고    scopus 로고
    • Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors
    • Sakamoto S, Hara Y, Mitamura T, Sassa S, Kudo H, Suzuki S, Kuwa K, Okayasu I and Shinoda H: Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors. Anti-Cancer Drugs 9: 351-357, 1998.
    • (1998) Anti-cancer Drugs , vol.9 , pp. 351-357
    • Sakamoto, S.1    Hara, Y.2    Mitamura, T.3    Sassa, S.4    Kudo, H.5    Suzuki, S.6    Kuwa, K.7    Okayasu, I.8    Shinoda, H.9
  • 16
    • 0023182429 scopus 로고
    • Relative activities of thyminidylate synthetase and thymidine kinase in 1,2-dimethylhydrazine-induced colon carcinomas in rats
    • Sakamoto S, Kuwa K, Tsukada K, Sagara T, Kasahara N and Okamoto R: Relative activities of thyminidylate synthetase and thymidine kinase in 1,2-dimethylhydrazine-induced colon carcinomas in rats. Carcinogenesis 8: 405-408, 1987.
    • (1987) Carcinogenesis , vol.8 , pp. 405-408
    • Sakamoto, S.1    Kuwa, K.2    Tsukada, K.3    Sagara, T.4    Kasahara, N.5    Okamoto, R.6
  • 17
    • 0015210983 scopus 로고
    • Thymidylate synthetase from amethopterin-resistant Lactobacillus casei
    • Dunlap RB, Harding NGL and Huennekens FM: Thymidylate synthetase from amethopterin-resistant Lactobacillus casei. Biochemistry 10: 88-97, 1971.
    • (1971) Biochemistry , vol.10 , pp. 88-97
    • Dunlap, R.B.1    Harding, N.G.L.2    Huennekens, F.M.3
  • 18
    • 0015522670 scopus 로고
    • Properties of thymidine kinase partially purified from human fetal and adult tissues
    • Taylor AT, Stafford MA and Jones OW: Properties of thymidine kinase partially purified from human fetal and adult tissues. J Biol Chem 247: 1930-1935, 1972.
    • (1972) J Biol Chem , vol.247 , pp. 1930-1935
    • Taylor, A.T.1    Stafford, M.A.2    Jones, O.W.3
  • 19
    • 0023753618 scopus 로고
    • Mechanism of innate resistance to thymidylate synthase inhibition after 5-fluorouracil
    • Spears CP, Gustavsson BG, Berne M, Frosing R, Bernstein L and Hays AA: Mechanism of innate resistance to thymidylate synthase inhibition after 5-fluorouracil. Cancer Res 48: 5894-5900, 1988.
    • (1988) Cancer Res , vol.48 , pp. 5894-5900
    • Spears, C.P.1    Gustavsson, B.G.2    Berne, M.3    Frosing, R.4    Bernstein, L.5    Hays, A.A.6
  • 20
    • 0022400840 scopus 로고
    • Enzymes of uracil catabolism in normal and neoplastic human tissues
    • Naguib FNM, El Kouni AM and ChaS: Enzymes of uracil catabolism in normal and neoplastic human tissues. CancerRes 45: 5405-5412, 1985.
    • (1985) CancerRes , vol.45 , pp. 5405-5412
    • Naguib, F.N.M.1    El Kouni, A.M.2    Cha, S.3
  • 22
    • 0029095796 scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts forresistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
    • Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, Stain S, Beart R and Danenberg P: Quantitation of intratumoral thymidylate synthase expression predicts forresistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial. Eur J Cancer 31: 1306-1310, 1995.
    • (1995) Eur J Cancer , vol.31 , pp. 1306-1310
    • Leichman, L.1    Lenz, H.J.2    Leichman, C.G.3    Groshen, S.4    Danenberg, K.5    Baranda, J.6    Spears, C.P.7    Boswell, W.8    Silberman, H.9    Ortega, A.10    Stain, S.11    Beart, R.12    Danenberg, P.13
  • 23
    • 0027313526 scopus 로고
    • Pathological features and pyrimidine nucleotide synthesis in human gastric carcinomas
    • Sakamoto S, Kawachi Y, Konishi T. Pathological features and pyrimidine nucleotide synthesis in human gastric carcinomas. Anticancer Res 13: 879-882, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 879-882
    • Sakamoto, S.1    Kawachi, Y.2    Konishi, T.3
  • 24
    • 0018274585 scopus 로고
    • Pathological of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine
    • Sunter JP, Appleton DR, Wright NA and Watson AJ: Pathological of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine. Virchows Arch B Cell Pathol 29: 211-223, 1978.
    • (1978) Virchows Arch B Cell Pathol , vol.29 , pp. 211-223
    • Sunter, J.P.1    Appleton, D.R.2    Wright, N.A.3    Watson, A.J.4
  • 25
    • 0028329522 scopus 로고
    • Gene dosage and expression, and enzyme activity of thymidine kinase and thymidylate synthase in xenografted colorectal adenocarcinomas
    • Lasserre C, Sabatier L, Beaumatin J, Luccioni C, Lefrancois D, Muleris M and Dutrillaux B: Gene dosage and expression, and enzyme activity of thymidine kinase and thymidylate synthase in xenografted colorectal adenocarcinomas. Int J Cancer 56: 506-511, 1994.
    • (1994) Int J Cancer , vol.56 , pp. 506-511
    • Lasserre, C.1    Sabatier, L.2    Beaumatin, J.3    Luccioni, C.4    Lefrancois, D.5    Muleris, M.6    Dutrillaux, B.7
  • 26
    • 0029149035 scopus 로고
    • The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate poolin human colorectal carcinoma tissues: Changes after tegafur and uracil treatment
    • Omura K, Kawakami K, Kanehira E, Nagasato A, Kawashima S, Tawaraya K, Watanabe S, Hirano K, Shirasaka T and Watanabe Y: The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate poolin human colorectal carcinoma tissues: Changes after tegafur and uracil treatment. Cancer Res 55: 3897-3901, 1995.
    • (1995) Cancer Res , vol.55 , pp. 3897-3901
    • Omura, K.1    Kawakami, K.2    Kanehira, E.3    Nagasato, A.4    Kawashima, S.5    Tawaraya, K.6    Watanabe, S.7    Hirano, K.8    Shirasaka, T.9    Watanabe, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.