Negative and positive regulation of the non-osmoregulated ompS1 porin gene in Salmonella typhi: A novel regulatory mechanism that involves OmpR

Molecular Microbiology

Volumn 32, Issue 2, 1999, Pages 243-252

  Oropeza, Ricardo ^a   Sampieri, Clara Luz ^a   Puente, José Luis ^a   Calva, Edmundo ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; NUCLEOTIDE; OUTER MEMBRANE PROTEIN; PORIN; PRIMER DNA;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA FLANKING REGION; ESCHERICHIA COLI; EXTENSION GENE; GENE DELETION; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OSMOLARITY; OSMOREGULATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN FAMILY; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM; SEQUENCE HOMOLOGY; STOP CODON;

ESCHERICHIA COLI; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM;

EID: 0032895882     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01329.x     Document Type: Article

References (42)

1. Abshire, K.Z., and Neidhardt, F.C. (1993) Analysis of proteins synthesized by Salmonella typhimurium during growth within a host macrophage. J Bacteriol 175: 3734-3743.
2. Aron, L., Faundez, G., González, C., Roessler, E., and Cabello, C. (1993) Lipopolysaccharide-independent radio-immunoprecipitation and identification of structural and in vivo induced immunogenic surface proteins of Salmonella typhi in typhoid fever. Vaccine 11: 10-17.
3. Barrios, H., Fischer, H.M., Hennecke, H., and Morett, E. (1995) Overlapping promoters for two different RNA polymerase holoenzymes control Bradyrhizobium japonicum nifA expression. J Bacteriol 177: 1760-1765.
4. Benz, R., Schmid, A., and Hancock, R.E.W. (1985) Ion selectivity of gram-negative bacterial porins. J Bacteriol 162: 722-727.
5. Blattner, F.R., Plunkett, III, G., Bloch, C.A., Perna, N.T., Burland, V., Rilley, M., et al. (1997) The complete genome sequence of Escherichia coli K-12. Science 277: 1453-1461.
6. Calderón, I., Lobos, S.R., Rojas, H.A., Palomino, C., Rodriguez, L.H., and Mora, G.C. (1986) Antibodies to porin antigens of Salmonella typhi induced during typhoid infection in humans. Infect Immun 57: 2136-2140.
7. Chatfield, S.N., Dorman, C.J., Hayward, C., and Dougan, G. (1991) Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both OmpC and OmpF are attenuated in vivo. Infect Immun 59: 449-452.
8. Dorman, C.J., Chatfield, S., Higgins, C.F., Hayward, C., and Dougan, G. (1989) Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: ompR mutants are attenuated in vivo. Infect Immun 57: 2136-2140.
9. Feavers, I.M., and Maiden, M.C.J. (1998) A gonococcal porA pseudogene: implications for understanding the evolution and pathogenicity of Neisseria gonorrhoeae. Mol Microbiol 30: 647-656.
10. Fernández-Mora, M., Oropeza, R., Puente, J.L., and Calva, E. (1995) Isolation and characterization of ompS1, a novel Salmonella typhi outer membrane protein-encoding gene. Gene 158: 67-72.
11. Forst, S., and Inouye, M. (1988) Environmentally regulated gene expression for membrane proteins in Escherichia coli. Annu Rev Cell Biol 4: 21-42.
12. Galdiero, F., Tufano, M.A., Sommese, L., Folgore, A., and Tedesco, F. (1984) Activation of complement system by porins extracted from Salmonella typhimurium. Infect Immun 46: 559-563.
13. Galdiero, F., L'Ero, G.C., Benedetto, N., Galdiero, M., and Tufano, M.A. (1993) Release of cytokines induced by Salmonella typhimurium porins. Infect Immun 61: 155-161.
14. Hancock, R.E.W. (1987) Role of porins in outer membrane permeability. J Bacteriol 169: 929-933.
15. Harley, C.B., and Reynolds, R.P. (1987) Analysis of E. coli promoter sequences. Nucleic Acids Res 15: 2343-2361.
16. Head, C.G., Tardy, A., and Kenney, L.J. (1998) Relative binding affinities of OmpR and OmpR-phosphate at the ompF and ompC regulatory sites. J Mol Biol 281: 857-870.
17. Huang, K.J., and Igo, M.M. (1996) Identification of the bases in the ompF regulatory region, which interact with the transcription factor OmpR. J Mol Biol 262: 615-628.
18. Huang, K.J., Schieberl, J.L., and Igo, M.M. (1994) A distant upstream site involved in the negative regulation of the Escherichia coli ompF gene. J Bacteriol 176: 1309-1315.
19. Inokuchi, K., Mutoh, N., Matsuyama, S.-I., and Mizushima, S. (1982) Primary structure of the ompF gene that codes for a major outer membrane protein of Escherichia coli K-12. Nucleic Acids Res 10: 6957-6967.
20. Isibasi, A., Ortíz, V., Vargas, M., Paniagua, J., González, C., Moreno, J., et al. (1988) Protection against Salmonella typhi infection in mice after immunization with outer membrane proteins isolated from Salmonella typhi 9, 12, d, Vi. Infect Immun 56: 2953-2959.
21. Itoh, T., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., et al. (1996) A 460 kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. DNA Res 3: 379-392.
22. Kawaji, H., Mizuno, T., and Mizushima, S. (1979) Influence of molecular size and osmolarity of sugars and dextrans on the synthesis of outer membrane proteins O-8 and O-9 of Escherichia coli K-12. J Bacteriol 140: 843-847.
23. Kuusi, N., Nurminen, M., Saxen, H., and Mäkela, P.H. (1981) Immunization with major outer membrane protein (porin) preparation in experimental murine salmonellosis: effect of lipopolysaccharide. Infect Immun 34: 328-332.
24. Lindgren, S.W., Stojiljkovic, I., and Heffron, F. (1996) Macrophage killing is an essential virulence mechanism of Salmonella typhimurium. Proc Natl Acad Sci USA 93: 4197-4201.
25. Martínez-Flores, I., Bustamante, V.H., Puente, J.L., and Calva, E. (1995) Cloning and characterization of the Salmonella typhi ompR and envZ genes. AsPac J Mol Biol Biotechnol 3: 135-144.
26. Martinez-Flores, I., Cano, R., Bustamante, V.H., Calva, E., and Puente, J.L. (1999) The ompB operon partially determines differential expression of OmpC in Salmonella typhi and Escherichia coli. J Bacteriol 181: 556-562.
27. Miller, J.H. (1972) Experiments in Molecular Genetics Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 352-355 and 403-404.
28. Mizuno, T., and Mizushima, S. (1990) Signal transduction and gene regulation through the phosphorylation of two regulatory components: the molecular basis for the osmotic regulation of the porin genes. Mol Microbiol 4: 1077-1082.
29. Muthukummar, S., and Muthukkaruppan, V.R. (1993) Mechanism of protective immunity induced by porin-lipopolysaccharide against murine salmonellosis. Infect Immun 61: 3017-3025.
30. Pang, T., Bhutta, Z.A., Finlay, B.B., and Altwegg, M. (1995) Typhoid fever and other salmonellosis: a continuing challenge. Trends Microbiol 3: 253-255.
31. Pickard, D., Jingli, L., Roberts, M., Maskell, D., Hone, D., Levine, M., et al. (1994) Characterization of defined ompR mutants of Salmonella typhi: ompR is involved in the regulation of Vi polysaccharide expression. Infect Immun 62: 3984-3993.
32. Pratt, L.A., Hsing, W., Gibson, K.E., and Silhavy, T.J. (1996) From acids to osmZ: multiple factors influence synthesis of the OmpF and OmpC porins in Escherichia coli. Mol Microbiol 20: 911-917.
33. Puente, J.L., Flores, V., Fernández, M., Fuchs, Y., and Calva, M. (1987) Isolation of an ompC-like outer membrane protein gene from Salmonella typhi. Gene 61: 75-83.
34. Puente, J.L., Verdugo-Rodríguez, A., and Calva, E. (1991) Expression of Salmonella typhi and Escherichia coli OmpC is influenced differently by medium osmolarity; dependence on Escherichia coli OmpR. Mol Microbiol 5: 1205-1210.
35. Puente, J.L., Juárez, D., Bobadilla, M., Arias, C.F., and Calva, E. (1995) The Salmonella ompC gene: structure and use as a carrier for heterologous sequences. Gene 156: 1-9.
36. Rampersaud, A., Harlocker, S.L., and Inouye, M. (1994) The OmpR protein of Escherichia coli binds to sites in the ompF promoter region in a hierarchical manner determined by its degree of phosphorylation. J Biol Chem 269: 12559-12566.
37. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
38. Shapira, S.T., Chou, J., Richaud, F.V., and Casadaban, M.J. (1983) New versatile plasmid vectors for expression of hybrid proteins coded by a cloned gene fused to lacZ gene sequences encoding an enzymatically active carboxy-terminal portion of β-galactosidase. Gene 25: 71-82.
39. Simons, R.W., Housman, F., and Kleckner, N. (1987) Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53: 85-96.
40. Tsui, P., Helu, V., and Freundlich, M. (1988) Altered osmoregulation of ompF in integration host factor mutants of Escherichia coli. J Bacteriol 170: 4950-4953.
41. Tufano, M.A., Berlingieri, M.T., Sommese, L., and Galdiero, F. (1984) Immune response in mice and effects on cells by outer membrane porins from Salmonella typhimurium. Microbiológica 7: 353-366.
42. Verdugo-Rodríguez, A., López-Vidal, Y., Puente, J.L., Ruíz-Palacios, G.M., and Calva, E. (1993) Early diagnosis of typhoid fever by an enzyme immunoassay using Salmonella typhi outer membrane protein preparations. Eur J Clin Microbiol Infect Dis 12: 248-254.