HHV-8/KSHV is not associated with AIDS-related primary central nervous system lymphoma

Brain Pathology

Volumn 9, Issue 2, 1999, Pages 199-208

  Antinori, Andrea ^a   Larocca, Luigi M ^a   Fassone, Lucia ^b   Cattani, Paola ^a   Capello, Daniela ^b   Cingolani, Antonella ^a   Saglio, Giuseppe ^c   Fadda, Giovanni ^a   Gaidano, Gianluca ^b   Ortona, Luigi ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIGEN; VIRUS DNA;

ARTICLE; BRAIN LYMPHOMA; BRAIN TISSUE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; DISEASE ASSOCIATION; DNA DETERMINATION; EPSTEIN BARR VIRUS; FEMALE; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; NEUROPATHOLOGY; SEQUENCE ANALYSIS;

EID: 0032895765     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.1999.tb00218.x     Document Type: Article

References (51)

1. Ahsan H, Neugut AI (1996) High risk of Kaposi's sarcoma and central nervous system lymphoma in the same individual: a finding related to acquired immunodeficiency syndrome. Int J Cancer 66:176-178.
2. Antinori A, Ammassari A, De Luca A, Cingolani A, Murri R, Scoppettuolo G, Fortini M, Tartaglione T, Larocca LM, Zannoni G, Cattani P, Grillo R, Roselli R, Iacoangeli M, Scerrati M, Ortona L (1997) Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiological characteristics combined with polymerase chain reaction assays in cerebrospinal fluid. Neurology 48:687-694.
3. Antinori A, Cingolani A, De Luca A, Gaidano G, Ammassari A, Larocca LM, Ortona L. (1999) Epstein-Barr virus in monitoring the response to therapy of AIDS-related primary central nervous system lymphoma. Ann Neurol 45: 259-261
4. Antinori A, De Rossi G, Ammassari A, Cingolani A, Murri R, Di Giuda D, De Luca A, Pierconti F, Tartaglione T, Scerrati M, Larocca LM, Ortona L. (1999) Value of combined approach with 201TI-single photon emission computed tomography (SPECT) and Epstein-Barr virus DNA polymerase chain reaction in cerebrospinal fluid for the diagnosis of AIDS-related primary central nervous system lymphoma. J Clin Oncol 17: 554-560
5. Bishop YMM, Fienberg SE, Holland PW (1975) Discrete multivariate analysis. MIT Press. Cambridge, MA.
6. Cattani P, Capuano M, Lesnoni La Parola I, Guido R, Santangelo R, Cerimele F, Masini C, Nanni G, Fadda G, Cerimele D (1998) Human herpesvirus 8 in Italian HIV-seronegative patients with Kaposi sarcoma. Arch Dermatol 134:695-699.
7. Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphoma. N Engl J Med 332:1186-1191.
8. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper Y, Knowles DM, Moore PS (1994) A identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266:1965-1969.
9. Cingolani A, De Luca A, Larocca LM, Ammassari A, Scerrati M, Antinori A, Ortona L (1998) Minimally invasive diagnosis of acquired immunodeficiency syndrome-related primary central nervous system lymphoma. J Natl Cancer Inst 90:364-369.
10. Cinque P, Vago L, Dahl H, Brytting M, Terrani MR, Fornara C, Racca S, Castagna A, D'Arminio Monforte A, Wahren B, Lazzarin A, Linde A (1996) Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus-associated opportunistic diseases of the central nervous system in HIV-infected patients. AIDS 10:951-958.
11. Corboy JR, Garl PJ, Kleinschmidt-DeMasters (1998) Human herpesvirus 8 DNA in CNS lymphomas from patients with and without AIDS. Neurology 50:335-340.
12. Coté TR, Manns A, Hardy CR, Yellin FJ, Hartge P, and the AIDS/Cancer Study Group (1996) Epidemiology of brain lymphoma among people with or without acquired immunodeficiency syndrome. J Natl Cancer Inst 88:675-679.
13. Epstein LG (1998) Does human herpesvirus 8 have a pathogenetic role in primary CNS lymphoma? Neurology 50:322-323.
14. Feichtinger H, Putkonen P, Parravicini C, Li S-L, Kaaya EE, Bottiger D, Biberfeld G, Biberfeld P (1990) Malignant lymphomas in cynomolgus monkeys infected with simian immunodeficiency virus. Am J Pathol 137:1311-1315.
15. Gaidano G, Capello D, Pastore C, Antinori A, Gloghini A, Carbone A, Larocca LM, Saglio G (1997) Analysis of human herpesvirus type 8 infection in AIDS-related and AIDS-unrelated primary central nervous system lymphoma. J Infect Dis 175:1193-1197.
16. Gaidano G, Pastore C, Gloghini A, Cusini M, Nomodedeu J, Volpe G, Capello D, Vaccher E, Bordes R, Tirelli U, Saglio G, Carbone A (1996) Distribution of human herpesvirus-8 sequences throughout the spectrum of AIDS-related neoplasia. AIDS 10:941-949.
17. Gao SJ, Kingsley L, Hoover DR, Spira TJ, Rinaldo CR, Saah A, Phair J, Detels R, Parry P, Chang Y, Moore PS (1996) Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med 335:233-241.
18. Gao SJ, Kingsley L, Li M, Zheng W, Parravicini C, Zieglesr J, Newton R, Rinaldo CR, Saah A, Phair J, Detels R, Chang Y, Moore PS (1996) KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med 2:925-928.
19. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JKC, Cleary ML, Delsos G, De Wolf-Peeters, Falini B, Gatter KC, Grogan TM, Isaacson PG, Knowles DM, Mason DY, Muller-Hermelink HK, Pileri SA, Piris MA, Ralfkiaer E, Warnke RA (1994) A revised european-american classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 84:1361-1392.
20. Jellinger KA, Paulus W (1995) Primary central nervous system lymphomas - new pathological developments. J Neurooncol 24:33-36.
21. Jones JL, Hanson DL, Ward JW (1998) Effect of antiretroviral therapy on recent trends in cancers among HIV-infected persons. The Second National AIDS Malignancy Conference. Bethesda, MD, April 6-8, [Abst S4]. J Acquir Immune Defic Syndr Hum Retrovirol 17:A39.
22. Kwok S, Higuchi R (1989) Avoiding false positives with PCR. Nature 339:237-238.
23. Larocca LM, Capello D, Rinelli A, Nori S, Antinori S, Gloghini A, Cingolani A, Migliazza A, Saglio G, Cammilleri-Broet S, Raphael M, Carbone A, Gaidano G (1998) The molecular and phenotypic profile of primary central nervous system lymphoma identifies distinct categories of the diseases and is consistent with histogenetic derivation from germinal center-related B-cells. Blood 92:1011-1019.
24. Lennette ET, Blackbourne DJ, Levy JA (1996) Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 348:858-861.
25. Levine AM (1993) AIDS-related malignancies: the emerging epidemic. J Natl Cancer Inst 85:1382-1397.
26. Liedtke W, Trubner K, Schwechheimer K (1995) On the role of human herpesvirus 6 in viral latency in nervous tissue and in cerebral lymphoma. J Neurol Sci 134:184-188.
27. Lin JC, Lin SC, Mar EC, Pellett PE, Stamey FR, Stuart JA, Spira TJ (1995) Is Kaposi's sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men. Lancet 346:1601-1602.
28. Luppi M, Barozzi P, Maiorana A, Artusi T, Trovato R, Marasca R, Savarino M, Ceccherini-Nelli L, Torelli G (1996) Human herpesvirus-8 DNA sequences in human immunodeficiency virus-negative angioimmunoblastic lymphadenopathy and benign lymphadenopathy with giant germinal center hyperplasia and increased vascularity. Blood 87:3903-3909.
29. MacKenzie J, Sheldon J, Morgan G, Cook G, Schultz TF, Jarret RF (1997) HHV-8/KSHV and multiple myeloma in the UK. Lancet 350:1144-1145.
30. MacMahon EME, Glass JD, Hayward SD, Mann RB, Scott BP, Charache P, McArthur JC, Ambinder RF (1991) Epstein-Barr virus in AIDS-related primary central nervous system lymphoma. Lancet 338:969-973.
31. Maggiorella MT, Monardo F, Koanga-Motomo ML, Cioe' L, Sernicola L, Corrias F, Baroni CD, Verani P, Titti F (1998) Detection of infectious simian immunodeficiency virus in B-and T-cell lymphomas of experimentally infected macaques. Blood 91:3103-3111.
32. Marcelin AG, Dupin N, Bouscary D, Bossi P, Cacoub P, Ravaud P, Calvez V (1997) HHV-8/KSHV and multiple myeloma in France. Lancet 350:1144.
33. Mikol J, Deplanche M, Moulinier A, Dupont B, Morinet F (1996) Herpesvirus-like DNA sequences in primary non-Hodgkin lymphomas of the central nervous system. J Neuropathol Exp Neurol 55:623.
34. Miller G, Rigsby MO, Heston L, Grogan E, Sun R, Metroka C, Levy JA, Gao SJ, Chang Y, Moore PS (1996) Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. N Engl J Med 334:1292-1297.
35. Monini P, De Lellis L, Fabris M, Rigolin F, Cassai E (1996) Kaposi's sarcoma-associated herpesvirus DNA sequences in prostate tissue and human semen. N Engl J Med 334:1168-1172.
36. Moore PS (1998) Human herpesvirus 8 variant. Lancet 351:679-680.
37. Moore PS, Chang Y (1995) Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma lesions from persons with and without HIV infection. N Engl J Med 332:1181-1185.
38. Moore PS, Kingsley L, Holmberg SD, Spira T, Gupta P, Hoover DR, Parry JP, Conley LJ, Jaffe HW, Chang Y (1996) Kaposi's sarcoma-associated herpesvirus infection prior to onset of Kaposi's sarcoma. AIDS 10:175-180.
39. Morgello S, Tagliati M, Ewart MR (1997) HHV-8/KSHV and AIDS-related CNS lymphoma. Neurology 48:1333-1335.
40. National Cancer Institute sponsored study of classifications of non-Hodgkin's lymphomas (1982). Summary and description of a Working Formulation for clinical usage. Cancer 49:2112-2135.
41. Paulus W, Jellinger K, Hallas C, Ott G, Muller-Hermelink HK (1993) Human herpesvirus-6 and Epstein-Barr virus genome in primary cerebral lymphoma. Neurology 43:1591-1993.
42. Rettig MB, Ma M, Pold M, Schiller G, Belson D, Savage A, Nishikubo C, Fraser J, Said JW, Barenson JR (1997) KSHV infection of multiple myeloma bone marrow stroma. Science 276:1851-1854.
43. Rezza G, Lennette ET, Giuliani M, Pezzotti P, Caprilli F, Monini P, Buttò S, Lodi G, Di Carlo A, Levy JA, Ensoli B (1998) Prevalence and determinants of anti-lytic and anti-latent antibodies to human herpesvirus-8 among italian individuals at risk of sexually and parenterally transmitted infections. Int J Cancer 77:361-365.
44. Said JW, Rettig MB, Heppner K, Vescio RA, Schiller G, Ma HJ, Belson D, Savage A, Shintaku IP, Koeffler HP, Asou H, Pinkus G, Pinkus J, Schrage M, Green E, Berenson JR (1997) Localization of Kaposi's sarcoma-associated herpesvirus in bone marrow biopsy samples from patients with multiple myeloma. Blood 90:4278-4282.
45. Simpson GR, Schultz TF, Whitby D, Cook PM, Boshoff C, Rainbow L, Howard MR, Gao SJ, Bohenzky RA, Simmonds P, Lee C, De Ruiter A, Hatzakis A, Tedder RS, Weller IVD, Weiss R, Moore PS (1996) Prevalence of Kaposi's sarcoma associated herpesvirus infection mesured by antibodies to recombinant capsid protein and latent immunofluorescent antigens. Lancet 348:1133-1138.
46. Smith MS, Bloomer C, Horvat R, Goldstein E, Casparian JM, Chandran B (1997) Detection of human herpesvirus 8 DNA in Kaposi's sarcoma lesions and peripheral blood of human immunodeficiency virus-positive patients and correlation with serologic measurements. J Infect Dis 176:84-93.
47. Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, Babinet P, D'Agai MF, Clauvel JP, Raphael M, Degos L, Sigaux F (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castelman's disease. Blood 86:1276-1280.
48. Tarte K, Holsen SJ, Lu ZY, Legouffe E, Rossi JF, Chang Y, Klein B (1998) Clinical-grade functional dentritic cells from patients with multiple myeloma are not infected with Kaposi's sarcoma-associated herpesvirus. Blood 91:1852-1857.
49. Whitby D, Howard MR, Tenant-Flowers M, Brink NS, Copas A, Boshoff C, Hatzioannou T, Suggett FEA, Aldam DM, Denton AS, Miller RF, Weller IVD, Weiss RA, Tedder RS, Schulz TF (1995) Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet 346:799-802.
50. Whitby D, Luppi M, Barozzi P, Boshoff C, Weiss RA, Torelli G (1998) Human herpesvirus 8 seroprevalence in blood donors and lymphoma patientsfrom different regions of Italy. J Natl Cancer Inst 90:395-397.
51. Yi Q, Ekman M, Anton D, Bergenbrant S, Österborg A, Georgii-Hemming P, Holm G, Nilsson K, Biberfeld P (1998) Blood dendritic cells from myeloma patients are not infected with Kaposi's sarcoma-associated Herpesvirus (KSHV/HHV-8). Blood 92:402-404.