Induction therapy with an intravenous loading dose of azathioprine for treatment of refractory, active rheumatoid arthritis

Arthritis and Rheumatism

Volumn 42, Issue 1, 1999, Pages 186-187

  Matteson, Eric L ^a   Orces, Carlos H ^a   Duffy, Joseph ^a   Lipsky, James J ^a   Pike, M Gennett ^a   Sandborn, William J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; GOLD DERIVATIVE; HYDROXYCHLOROQUINE; METHOTREXATE; PREDNISONE; SALAZOSULFAPYRIDINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; FEVER; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RELAPSE; RHEUMATOID ARTHRITIS; TREATMENT FAILURE; VAGINA CANDIDIASIS;

ARTHRITIS, RHEUMATOID; AZATHIOPRINE; ERYTHROCYTES; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; THIOGUANINE;

EID: 0032895399     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199901)42:1<186::AID-ANR23>3.0.CO;2-Y     Document Type: Article

References (5)

1. Sandborn WJ, van Os EC, Zins BJ, Tremaine WJ, Mays DC, Lipsky JJ. An intravenous loading dose of azathioprine decreases the time to response in patients with Crohn's disease. Gastroenterology 1995;109;1808-17.
2. Hochberg MC, Chang RW, Dwosh I, Lindsey S, Pincus T, Wolfe F. The American College of Rheumatology 1991 revised criteria for the classification of global functional status in rheumatoid arthritis. Arthritis Rheum 1992;35:498-502.
3. Lennard L, van Loon JA, Weinshilboum RN. Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism. Clin Pharmacol Ther 1989;46:149-54.
4. Erdmann GR, France LA, Bostrom BC, Canafax DM. A reversed phase high-performance liquid chromatography approach in determining total red blood cell concentrations of 6-thioguanine. 6-mercaptopurine, methylthioguanine, and methylmercaptopurine in a patient receiving thiopurine therapy. Biomed Chromatogr 1990;4:47-51.
5. Felson DT, Andersen JJ, Boers M, Bombardier C, Chernoff M, Fried B, et al. The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. Arthritis Rheum 1993;36:729-40.