Immunomodulatory effects of interferon-γ on autoreactive nephritogenic T-cell clones

Kidney International

Volumn 55, Issue 4, 1999, Pages 1395-1406

  Meyers, Catherine M ^a,b,c   Zhang, Youkang ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Autoimmunity; Cytokines; Graft vs. host disease; MHC; Nephritis; T cell lymphocyte

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; GLOMERULONEPHRITIS; HISTOPATHOLOGY; IMMUNOMODULATION; IMMUNOPROPHYLAXIS; INTRAPERITONEAL DRUG ADMINISTRATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE TRANSFER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; T LYMPHOCYTE SUBPOPULATION;

EID: 0032894368     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00394.x     Document Type: Article

References (56)

1. GLEICHMANN E, GLEICHMANN H, WILKE W: Autoimmunization and lymphomagenesis in parent-F1 combinations differing at the major histocompatibility complex: Model for spontaneous disease caused by altered self-antigens? Transplant Rev 31:156-224, 1976
2. VAN RAPPARD-VAN DER VEEN FM, RADASZKIEWICZ T, TERRANEO L, GLEICHMANN E: Attempts at standardization of lupus-like graft-vs-host disease: Inadvertent repopulation by DBA/2 spleen cells of H-2-different nonirradiated F1 mice. J Immunol 130:2693-2701, 1983
3. ROLINK AG, GLEICHMANN H, GLEICHMANN E: Diseases caused by reactions of T lymphocytes to incompatible structures of the major histocompatibility complex. VII. Immune-complex glomerulonephritis. J Immunol 130:209-215, 1983
4. ROLINK AG, RADASZKIEWICZ T, MELCHERS F: The autoantigen-binding B cell repertoires of normal and of chronically graft-versus-host-diseased mice. J Exp Med 165:1675-1687, 1987
5. VAN DER VEEN F, ROLINK AG, GLEICHMANN E: Diseases caused by reactions of T lymphocytes to incompatible structures of the major histocompatibility complex. IV. Autoantibodies to nuclear antigens. Clin Exp Immunol 46:589-596, 1981
6. GLEICHMANN E, VANELVEN EH, VAN DER VEEN JPW: A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation: Preferential formation of autoantibodies characteristic of SLE. Eur J Immunol 12:152-159, 1982
7. PORTANOVA JP, CLAMAN HN, KOTZIN BL: Autoimmunization in murine graft-vs-host disease I. Selective production of antibodies to histones and DNA. J Immunol 135:3850-3856, 1985
8. GLEICHMANN E, PALS ST, ROLINK AG, RADASZKIEWICZ T, GLEICHMANN H: Graft-versus-host reactions: Clues to the etiopathology of a spectrum of immunological diseases. Immunol Today 5:324-332, 1984
9. VIA CS, SHEARER GM: T cell interactions in autoimmunity: Insights from a murine model of graft-versus-host disease. Immunol Today 9:207-213, 1988
10. BILLIAU A: Interferon-γ: Biology and role in pathogenesis. Adv Immunol 62:61-130, 1996
11. MEYERS CM, TOMASZWESKI JH, GLASS JD, CHEN CW: The nephritogenic T cell response in murine chronic graft-vs-host disease. J Immunol 161:5321-5330, 1998
12. FIORENTINO DF, BOND MW, MOSMANN TR: Two types of mouse helper T cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 170:2081-2095, 1989
13. GUYRE PM, MORGANELLI PM, MILLER R: Recombinant immune interferon increases immunoglobulin G Fe receptors on cultured human mononuclear phagocytes. J Clin Invest 72:393-397, 1983
14. DUSTIN ML, SINGER KH, TUCK DT, SPRINGER TA: Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by Interferon γ and is mediated by intercellular adhesion molecule 1 (ICAM-1). J Exp Med 167:1323-1340, 1988
15. FREEDMAN AS, FREEMAN GJ, RHYNHART K, NADLER LM: Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol 137:429-437, 1991
16. HALLORAN PF, JEPHTHAT-OCHOLA J, URMSON J, FARKAS S: Systemic immunologic stimuli increase class I and II antigen expression in mouse kidney. J Immunol 135:1053-1060, 1985
17. HAVERTY TP, WATANABE M, NEILSON EG, KELLY CJ: Protective modulation of class II MHC gene expression in tubular epithelium by target antigen-specific antibodies: Cell-surface directed down-regulation of transcription can influence susceptibility 10 murine tubulointerstitial nephritis. J Immunol 143:1133-1141, 1989
18. WUTHRICH RP, GLIMCHER LH, YUI MA, JEVNIKAR AM, DUMAS SE, KELLEY VE: MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells. Kidney Int 37:783-789, 1990
19. FONG TAT, MOSMANN TR: The role of IFN-γ in delayed-type hypersensitivity mediated by Th1 clones. J Immunol 143:2887-2893, 1989
20. + T cell line that mediates murine interstitial nephritis. J Clin Invest 88:408-416, 1991
21. MOORE KW, WIEIRA P, FIORENTINO DF, TROUNSTINE ML, KHAN TA, MOSMANN TR: Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein Barr Virus gene BCRFI. Science 248:1230-1234, 1990
22. GRAY PW, GOEDDEL DV: Cloning and expression of murine immune interferon cDNA. Proc Natl Acad Sci USA 80:5842-5846, 1983
23. LAKKIS FG, CRUET EN: Cloning of rat interleukin-13 (IL-13) cDNA and analysis of IL-13 gene expression in experimental glomerulonephritis. Biochem Biophys Res Commun 197:612-618, 1993
24. PERNIS A, GUPTA G, GOLLOB KJ, GARFEIN E, COFFMAN RL, SCHINDLER C, ROTHMAN P: Lack of interferon γ receptor β chain and the prevention of interferon γ signaling in TH1 cells. Science 269:245-247, 1995
25. ALONSO S, MINTY A, BOURLET Y, BUCKINGHAM M: Comparison of three actin-coding sequences in the mouse: Evolutionary relationships between the actin genes of warm-blooded vertebrates. J Mol Evol 23:11-22, 1986
26. ARMITAGE P, BERRY G: Statistical Methods in Medical Research, Boston, Blackwell Scientific, 1987, p 559
27. GAJEWSKI TF, FITCH FW: Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol 140:4245-4252, 1988
28. GAJEWSKI TF, JOYCE J, FITCH FW: Antiproliferative effect of IFN-γ in immune regulation. III. Differential selection of Th1 and Th2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ. J Immunol 143:15-22, 1989
29. MEYERS CM, KELLY CJ: Inhibition of murine nephritogenic effector T cells by a clone-specific suppressor factor. J Clin Invest 94:2093-2104, 1994
30. 1: Suppression of a nephritogenic murine T cell clone. Kidney Int 46:1295-1301, 1994
31. BACH EA, SZABO SJ, DIGHE AS, ASHKENAZI A, AGUET M, MURPHY KM, SCHREIBER RD: Ligand-induced autoregulation of IFN-γ receptor β chain expression in T helper cell subsets. Science 270:1215-1218, 1995
32. FASLER S, AVERSA G, TERR A, THESTRUP-PEDERSEN K, DE VRIES JE, YSSEL H: Peptide-induced anergy in allergen-specific human Th2 cells results in lack of cytokine production and B cell help for IgE synthesis. J Immunol 155:4199-4206, 1995
33. DIAZ GALLO C, JEVNIKAR AM, BRENNAN EC, FLORQUIN S, PACHECO-SILVA A, RUBIN KELLEY V: Autoreactive kidney-infiltrating T-cell clones in murine lupus nephritis. Kidney Int 42:851-859, 1992
34. SAOUDI A, CASTEDO M, NOCHY D, MANDET C, PASQUIER T, DRUET P, PELLETIER L: Self-reactive anti-class II T helper type 2 cell lines derived from gold salt-injected rats trigger B cell polyclonal activation and transfer autoimmunity in CD8-depleted normal syngeneic recipients. Eur J Immunol 25:1972-1979, 1995
35. MARFAING-KOKA A, DEVERGNE O, GORGONE G, PORTIER A, SCHALL TJ, GALANAUD P, EMILIE D: Regulation of the production of the RANTES chemokine by endothelial cells: Synergistic induction by IFN-gamma plus TNF-α and inhibition by IL-4 and IL-13. J Immunol 154:1870-1878, 1995
36. LARNER AC, PETRICOIN EF, NAKAGAWA Y, FINBLOOM DS: IL-4 attenuates the transcriptional activation of both IFN-α and IFN-γ-induced cellular gene expression in monocytes and monocytic cell lines. J Immunol 150:1944-1950, 1993
37. PELEMAN R, WU J, FARGEAS C, DELESPESSE G: Recombinant interleukin 4 suppresses the production of interferon gamma by human mononuclear cells. J Exp Med 170:1751-1756, 1989
38. CHOMARAT P, RISSOAN M-C, BANCHEREAU J, MIOSSEC P: Interferon gamma inhibits interleukin 10 production by monocytes. J Exp Med 177:523-527, 1993
39. BACH EA, AGUET M, SCHREIBER RD: The IFN gamma receptor: A paradigm for cytokine receptor signaling. Anna Rev Immunol 15:563-591, 1997
40. SAKATSUME M, FINBLOON DS: Modulation of the expression of the IFN-γ receptor β-chain controls responsiveness to IFN-γ in human peripheral blood T cells. J Immunol 156:4160-4166, 1996
41. MINTY A, CHALON P, DEROCQ JM, DUMONT X, GUILLEMONT JC, KAGHAD M, LABIT C, LEPLATOIS P, LIAUZUN P, MILOUX B, MINTY C, CASELLAS P, LOISON G, LUPKER J, SHIRE D, FERRARA P, CAPUT D: Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 362:248-250, 1993
42. UMLAND SP, RAZAC S, MAHREBNE DK, SEYMOUR BW: Effects of in vivo administration of Interferon (IFN)-γ anti-IFN-γ or anti-interleukin-4 monoclonal antibodies in chronic autoimmune graft-versus-host disease. Clin Immunol Immunopathol 63:66-73, 1992
43. KAWAKAMI Y, KUZUYA N, WATANABE T, UCHIYAMA Y, YAMASHITA K: Induction of experimental thyroiditis in mice by recombinant interferon γ administration. Acta Endocrinol 122:41-48, 1990
44. TANG H, MIGNON-GODEFROY K, MERONI PL, GAROTTA G, CHARREIRE J, NICOLETTI F: The effects of a monoclonal antibody to interferon-gamma on experimental autoimmune thyroiditis (EAT): Prevention of disease and decrease of EAT-specific T cells. Eur J Immunol 23:275-278, 1993
45. CAMPBELL IL, KAY TWH, OXBROW L, HARRISON LC: Essential role for interferon-γ and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice. J Clin Invest 87:739-742, 1991
46. HEREMANS S, BILLIAU A, COLOMBATTI A, HILGERS J, DESOMER P: Interferon treatment of NZB mice: Accelerated progression of autoimmune disease. Infect Immunol 21:925-931, 1978
47. JACOB CO, VAN DER MEIDE PH, MCDEVITT HO: In vivo treatment of (NZB X NZW) F1 lupus-like nephritis with monoclonal antibody to gamma interferon. J Exp Med 166:798-803, 1987
48. BILLIAU A, HEREMANS H, VANDERKERCKHOVE F, KUKMANS R, SOBIS H, MEULEPAS E, CARTON H: Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma. J Immunol 140:1506-1510, 1988
49. VOORTHUIS JAC, UITDEHAAG BMJ, DEGROOT C, GOEDE PH, VAN DER MEIDE PH, DIJKSTRA CD: Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in rats. Clin Exp Immunol 81:183-188, 1990
50. FERBER IA, BROCKE S, TAYLOR-EDWARDS C, RIDGWAY W, DINISCO C, STEINMAN L, DALTON D, FATHMAN CG: Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis. J Immunol 156:5-7, 1996
51. JACOB CO, HOLOSHITZ J, VAN DER MEIDE P, STROBER S, MCDEVITT HO: Heterogeneous effects of IFN-γ in adjuvant arthritis. J Immunol 142:1500-1505, 1989
52. PRUD'HOMME GJ, PARFREY NA, VANIER LE: Cyclosporine-induced autoimmunity and immune hyperreactivity. Autoimmunity 9:345-356, 1991
53. PARFREY NA, PRUD'HOMME GJ: Patterns of MHC antigenic modulation in cyclosporine-induced autoimmunity. Am J Pathol 136:479-486, 1990
54. HESS A: Syngeneic graft-vs-host disease, in Graft-vs.-Host Disease: Immunology, Pathophysiology, and Treatment, edited by BURAKOFF SJ, DEEG HJ, FERRARA J, ATKINSON K, New York, Marcel Dekker, 1990, pp 95-108
55. JEVNIKAR AM, SINGER GG, COFFMAN T, GLIMCHER LH, RUBIN-KELLEY VE: Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury. J Am Soc Nephrol 3:1972-1977, 1993
56. ADAMS RB, PLANCHONE SM, ROCHE JK: IFN-γ modulation of epithelial harrier function: Time course, reversibility, and site of cytokine binding. J Immunol 150:2356-2363, 1993